Protein Alignment kek2 and LOC1280094

DIOPT Version :10

• Sequence 1: NP_523551.1
• Gene: kek2 / 34582
• FlyBaseID: FBgn0015400
• Length: 894
• Species: Drosophila melanogaster
• Sequence 2: XP_061512976.1
• Gene: LOC1280094 / 1280094
• VectorBaseID: AGAMI1_005275
• Length: 812
• Species: Anopheles gambiae
• Alignment Length: 877
• Identity: 252/877 - (28%)
• Similarity: 356/877 - (40%)
• Gaps: 222/877 - (25%)

  Fly     4 LPIWIPLLALLAITAA-----------CPPEVCVCKWKGGKQTVECGGQQLSNLPEGMDPGTQVL 57
            :|:.:.||.:|.:.|.           | |..|.||||||||.|||....|..:||.:|..||||
Mosquito    44 MPVLLSLLLVLLLPAIVSRGQVSGEPNC-PSACQCKWKGGKQAVECLSGNLFTIPENIDHSTQVL 107

  Fly    58 NFSGNALQVLQSERFLRMDLLNLQKIYLSRNQLIRIHEKAFRGLTNLVELDLSENALQNVPSETF 122
            :.|||.||::.:|.|:|.:||||||:|:...::.:|.:.||.|||||||||||.|.|..|||..|
Mosquito   108 DVSGNNLQIISNETFVRSNLLNLQKLYMRDCRIGQIDDGAFAGLTNLVELDLSINLLTAVPSAAF 172

  Fly   123 QDYSSLMRLSLSGNPIRELKTSAFRHLSFLTTLELSNCQVERIENEAFVGMDNLEWLRLDGNRIG 187
            |...||..|:|:.|.|:::::.|||:::.||.|:||.|.::.|..:||.|:.:|..|:|:||::
Mosquito   173 QHIVSLRDLTLARNHIQKIESHAFRNVTALTKLDLSFCSIQTIAPQAFEGLGSLHSLKLNGNQL- 236

  Fly   188 FIQGTHILPKS------LHGISLHSNRWNCDCRLLDIHFWLVNYNTPLAEEPKCM-EPARLKGQV 245
                :.:.||:      ||||.||.|.|.|||||.....||..:|.|....|.|. .|.|:..:.
Mosquito   237 ----SELRPKTIETLSRLHGIELHGNPWVCDCRLRAAKLWLTEHNIPYPIAPTCAGGPERVMDKT 297

  Fly   246 IKSLQREQLACLPEVSPQSSYTEVSEGRNMSITCLVRAIPEPKVLWLFNGQVMSNDSLMDNLHMY 310
            ...||.:..||.||:.|...:.:...|.|.:|.|...|:|...|.|.:||:::.|:|     |..
Mosquito   298 FGELQVDDFACKPEMLPVRRFIQSYSGENATIECRSSAVPSATVNWYWNGKLLVNNS-----HFS 357

  Fly   311 YYIDETIGVSGAEEKRSEIFIYNVGAEDNGTFSCVGQNIAGTTFSNYTLRVIIKEPPVVNEVSFP 375
            .|....:...|..||||.:.:.|....|:..|.||.:|.|||..:|:||.|.::      :|.|.
Mosquito   358 AYQRVLVHEQGNFEKRSRLTLTNAQETDSSEFYCVVENRAGTAEANFTLHVAMR------DVGFV 416

  Fly   376 RDYMNYIVASSAGGGIIFVVLLCTIVVKCKKTSEPAKQRKKCDQVTSIAGGTDSSTGSTQDTGMG 440
            .:....|..|:|...:|..:||..:.:..:....|..:.|..:||..|...:.||
Mosquito   417 IENRQVIGLSAALVILILFILLIILFLLVRLRRIPMTETKTPNQVEVITSVSPSS---------- 471

  Fly   441 MMKCASILNDGGDSMNGNPGLLLGDTLTPTKAANGAAGGGIILGNQMKQNLLLYATPNSAQQQLQ 505
                         ::||.....:.|..:|.:|.  |||.             |...||.|...||
Mosquito   472 -------------NVNGKVATPINDCHSPDRAK--AAGD-------------LKCGPNPAANPLQ 508

  Fly   506 LNVNLMGTGPGSPPLLLS--------NGHG--LAAAYC--SPPASLRNYQEKNPDLVND------ 552
                       .||.|..        :|.|  :|:..|  ||..||..   .||||:||
Mosquito   509 -----------KPPRLTDLPYSTSHYDGGGSLIASGQCFVSPTHSLAG---NNPDLINDTKRLGS 559

  Fly   553 --------------------AESVKH----------KLKTAVSL------DGAGEYETQSDCGQY 581
                                |:.:.|          .|.||:||      .|:|||..
Mosquito   560 GTDLTAATAAPGPAVPGGGVADPLAHLGQLQLQATSALSTALSLMDPVERPGSGEYSR------- 617

  Fly   582 EGCYQLAAAPHPHQGHQHPHPGHPLMGRFAQAMTTLPRGMQLKPAPHQVDVHLNPVCFLGQDGSF 646
            .||..|    :| .|....|..:       .|.|.|..|....|.|:.     :.:..||..||.
Mosquito   618 AGCDSL----YP-SGLWETHSSN-------LAATGLDHGGSHGPGPYS-----DKLPILGGGGSG 665

  Fly   647 AYDYSSAHMVQQPPQQQQQQQQVQPANNFYRTLPHNRLHKQQQFQAAAAAGGNVG---------- 701
            |           .|.......:....:...||.|...|.........|::||:.|
Mosquito   666 A-----------GPAMLNLDDETSSVDYLSRTFPRTHLTGGLSLSTTASSGGSYGHGVAAAAAAA 719

  Fly   702 VGGNPTLRYSLEAEFIQRGPTVSY-EKYQLPNV-------RFTAEGYPQQQQQQQQQLQQQQQLQ 758
            .||..|           .|....| ..|.||.|       ...|.|.|.............:.|:
Mosquito   720 TGGTTT-----------TGSGGGYPADYGLPIVPGAEQLHNKLASGQPAHHGSTGSMPMNAKTLR 773

  Fly   759 LQQQHQFP-----------------SPPEGYK 773
            :.|:...|                 ||.|||:
Mosquito   774 VWQKGGVPVLPPVTALKRALSNSRNSPDEGYQ 805

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kek2	NP_523551.1	LRR	<34..>204	CDD:443914	78/175 (45%)
		leucine-rich repeat	34..52	CDD:275380	7/17 (41%)
		leucine-rich repeat	54..79	CDD:275380	13/24 (54%)
		leucine-rich repeat	80..103	CDD:275380	9/22 (41%)
		leucine-rich repeat	104..127	CDD:275380	14/22 (64%)
		leucine-rich repeat	128..151	CDD:275380	8/22 (36%)
		leucine-rich repeat	152..175	CDD:275380	10/22 (45%)
		leucine-rich repeat	176..198	CDD:275380	6/21 (29%)
		LRRCT	207..256	CDD:214507	17/49 (35%)
		Ig_3	258..348	CDD:464046	27/89 (30%)
LOC1280094	XP_061512976.1	None