Protein Alignment kek2 and LOC1273631

DIOPT Version :10

• Sequence 1: NP_523551.1
• Gene: kek2 / 34582
• FlyBaseID: FBgn0015400
• Length: 894
• Species: Drosophila melanogaster
• Sequence 2: XP_312632.6
• Gene: LOC1273631 / 1273631
• VectorBaseID: AGAMI1_010950
• Length: 912
• Species: Anopheles gambiae
• Alignment Length: 938
• Identity: 206/938 - (21%)
• Similarity: 344/938 - (36%)
• Gaps: 180/938 - (19%)

  Fly    25 CVCKWKGGKQTVECGGQQLSNLPEGMDPGTQVLNFSGNALQVLQSERFLRMDLLNLQKIYLSRNQ 89
            |.|.||.|:::.:|..|:|..:|:.:....|:|:.|.|.:..|.::.|......||||:||..|.
Mosquito    73 CKCSWKSGRKSADCTNQRLPVVPQELSNELQILDLSHNQIDELPAKTFEAAHQTNLQKLYLRHNS 137

  Fly    90 LIRIHEKAFRGLTNLVELDLSENALQNVPSETFQDYSSLMRLSLSGNPIRELKTSAFRHLSFLTT 154
            :.|:...|||.||.|:|||::.|.|..:.:..|.|.:.:..:.|:.|.|..:..:.|..|.:||.
Mosquito   138 MKRVDRDAFRNLTILIELDMANNNLTALEAGVFDDLTKIRVIILNNNQIERIDKNLFYGLQYLTK 202

  Fly   155 LELSNCQVERIENEAFVGMDNLEWLRLDGNRIGFIQGTHI--LPKSLHGISLHSNRWNCDCRLLD 217
            :.|...::.||...:||.:.||..:.||.|.:..::....  |.| |..:||.:|.|||.|.|..
Mosquito   203 VHLRTNRLVRIALNSFVNVPNLSQIELDYNELQALRKESFSGLEK-LTSLSLTNNPWNCSCTLRS 266

  Fly   218 IHFWLVN---YNTPLAEEPKCMEPARLKGQVIKSLQREQLACLPEVSPQSSYTEVSEGRNMSITC 279
            ...:::.   |.:|.|    |..|..|.|:....::.:..||.|.: .::.......|.|.:..|
Mosquito   267 FAEYVLAKNLYTSPTA----CSVPKVLAGRQWTEIELDDFACPPAI-VENRMQFPGAGENATFIC 326

  Fly   280 LVRAIPEPKVLWLFNGQVMS-NDSLMDNLHMYYYIDETIGVSGAEEKR---SEIFIYNVGAEDNG 340
            .|..:|.||:.|||..:..| :|..:       .:.|.:..|..::..   ||:.|..|...|.|
Mosquito   327 KVTGLPLPKIDWLFQKRSFSRHDQRL-------RVTEAVRTSPRDQSEVLVSELTIVGVRPSDRG 384

  Fly   341 TFSCVGQNIAGTTFSN--YTLRVIIKEPPVVNEVSFPRDYMNYIVASSAGGGIIFVVLLCTIV-- 401
            |:.|...|..|...|.  :.|:.   :|..:...:..:|.:..::.      ::.||||..|:
Mosquito   385 TYVCKATNRGGIDESEQFFDLKA---DPHPITSATRSKDILQIVLI------VVVVVLLFVILSW 440

  Fly   402 -----VKCKKTSEPAKQRKKCDQVTSIAGGTDSSTGSTQDTGMGMMKCASILNDGGDSMNGNPGL 461
                 :.|:|     ::.||        .......|......|...:..|||:.|...::....|
Mosquito   441 VLVYCICCRK-----RRFKK--------NSAMRENGQMNTKMMDKSQNESILDGGSVMVDMQKSL 492

  Fly   462 L--LGDTLTPTKAAN--------GAAGGGIILGNQMKQN----LLLYATPNSAQQQLQLNVNLMG 512
            |  :.....|.:.|:        |:.|...:.|:..:::    .||..|...||.:...:|.|..
Mosquito   493 LTEVNPVEKPPRRADIDAGEKGPGSGGQSSVGGDYDEKHEAKRTLLEETGFVAQDEETASVALSD 557

  Fly   513 TGPGSPPLLLSNGHG---------LAAAYCSPP---ASLRNYQE-----KNPDLVNDAESVKHKL 560
            :.|.|....:.:|.|         ..|.:...|   :|:.|..:     |:|     ..|..::.
Mosquito   558 SNPRSRATFVDDGCGTNLPPDLLAFPARFPQSPSIQSSMSNIHDGRIYGKSP-----LASPIYQT 617

  Fly   561 KTAVSLDGAGEYETQSDCGQYEGCYQLAAAPHPHQGHQHPHPG--------------------HP 605
            ....||.|...                |..|...:..|||..|                    :|
Mosquito   618 GPGTSLGGGAS----------------AQMPAGFRTLQHPKTGRTIAIAAARSNSPFTPAPLIYP 666

  Fly   606 LMGRFAQAMTTLPRGMQLKPA-----PHQVDVHLNPVCFLGQDGSFAYDYSSAHMVQQPPQQQQQ 665
            .:....|...|:|| .|..|:     ...|...|.|....|..|:.:........:.:|......
Mosquito   667 PLALKHQGYVTIPR-KQRTPSWTPSMSSAVTAELLPAGSAGHSGATSPTSPIDLSLGEPVYDNLG 730

  Fly   666 QQQVQPANNFYRTLPHNRLHKQQQFQAAAAAGGNVGVGGNPTLRYSLEAEFIQRGPTVSYEKYQL 730
            .:.....|:   ||..|:...:.....:.|||  ..:...|..:||::...:   |.....:...
Mosquito   731 LRTTASGNS---TLKLNKTGLRGTPLGSTAAG--TALTSTPMAKYSMKDRPL---PATPGGQTAT 787

  Fly   731 PNVRFTAEGYPQQQQQQQQQLQQQQQLQLQQQHQFPSPPEGYKSDLAVMPAPFQQWPSC----LP 791
            ||......|                      ...:.:.||.         .|:....|.    |.
Mosquito   788 PNSSLLGHG----------------------GGNYEAIPEA---------LPYGAGQSMVAGGLS 821

  Fly   792 GYRFAQSPTSLPAVATPPPAAVVATPPPPTSAVSTQSTATSTIPELDESEASSPRLEEAAGSAAP 856
            |:...||....|.|.|....:.|...|||.........|...|....:.::|:|     :|..|.
Mosquito   822 GFDLDQSSIYGPVVGTTTNRSKVPPRPPPKPKKKVVLPAAGGIVTTGDDQSSAP-----SGQMAT 881

  Fly   857 PAGEEESSDTAKLKQLNGPL-ADSPDEG 883
            ..|:....:|:.......|| |:..|:|
Mosquito   882 AGGDSSGINTSTTNTSTSPLVAEDCDDG 909

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kek2	NP_523551.1	LRR	<34..>204	CDD:443914	51/171 (30%)
		leucine-rich repeat	34..52	CDD:275380	4/17 (24%)
		leucine-rich repeat	54..79	CDD:275380	6/24 (25%)
		leucine-rich repeat	80..103	CDD:275380	11/22 (50%)
		leucine-rich repeat	104..127	CDD:275380	8/22 (36%)
		leucine-rich repeat	128..151	CDD:275380	5/22 (23%)
		leucine-rich repeat	152..175	CDD:275380	7/22 (32%)
		leucine-rich repeat	176..198	CDD:275380	5/23 (22%)
		LRRCT	207..256	CDD:214507	13/51 (25%)
		Ig_3	258..348	CDD:464046	23/93 (25%)
LOC1273631	XP_312632.6	None