Protein Alignment kek2 and lrrn1

DIOPT Version :10

• Sequence 1: NP_523551.1
• Gene: kek2 / 34582
• FlyBaseID: FBgn0015400
• Length: 894
• Species: Drosophila melanogaster
• Sequence 2: XP_002938357.1
• Gene: lrrn1 / 100492182
• XenbaseID: XB-GENE-18030784
• Length: 718
• Species: Xenopus tropicalis
• Alignment Length: 504
• Identity: 119/504 - (23%)
• Similarity: 182/504 - (36%)
• Gaps: 183/504 - (36%)

  Fly    22 PEVCVCK---WKGGKQ------TVECGGQQLSNLPEGMDPGTQVLNFSGNAL------------- 64
            |::|||:   |...:.      ||:|...:|:.:|..:...||||....|.:
 Frog    34 PQLCVCEIRPWFTPQSTYREATTVDCNDLRLTKIPANLSLDTQVLLLQSNNIGKTNGELQRLFNL 98

  Fly    65 --------------------------------QVLQSERFLRMDLLNLQKIYLSRNQLIRIHEKA 97
                                            |:.:...:...||:|||::|::.|||..|...|
 Frog    99 TELDLSQNNFTSIQDVGLSNLSQLTTLHLEENQIFEMTDYCLQDLINLQELYINHNQLNSISPSA 163

  Fly    98 FRGLTNLVELDLS---------------------------------------------------- 110
            |.||.||:.|.|:
 Frog   164 FSGLRNLLRLHLNSNKLRIIDSRWFESTPNLEILMIGENPVIGILDFNFQPLVNLRSLVLAGMYL 228

  Fly   111 --------------------ENALQNVPSETFQDYSSLMRLSLSGNPIRELKTSAFR-------- 147
                                :|.|..||....|...:|..|.|:.||||:::...|:
 Frog   229 SDIPGNALLGLDNLESLSFYDNKLSKVPQLALQKVPNLKFLDLNKNPIRKIQEGDFKNMLKLKEL 293

  Fly   148 -----------------HLSFLTTLE-LSNCQVERIENEAFVGMDNLEWLRLDGNRIGFI-QGT- 192
                             :|..||.|| .:|.::..|...||..:..||.|.|:.|.:..: :||
 Frog   294 GINNMAELVSVDRNALENLPELTKLEATNNPKLSYIHRSAFRNVPTLESLMLNNNALNSVYRGTV 358

  Fly   193 HILPKSLHGISLHSNRWNCDCRLLDIHFWLVNYNTPLA-EEPK---CMEPARLKGQVIKSLQREQ 253
            ..|| :|..||:|||...|||.|    .|:.:..|.:. .||.   |..|...:||.:|....:.
 Frog   359 ESLP-NLREISIHSNPLRCDCVL----HWMGSNQTSIRFMEPLSMFCALPPEYRGQPVKEALAQD 418

  Fly   254 LA---CLPEVSPQS--SYTEVSEGRNMSITCLVRAIPEPKVLWLFN-GQVMSNDSLMDNLHMYYY 312
            .|   |||.:|..:  |:..:..|..:|:.|...|.|||::.|:.. |..::.::|.|..|:
 Frog   419 PAGEQCLPMISQDTFPSHLSLDIGMTVSLDCRAMAEPEPEIYWVTPLGHKVTTETLSDKYHL--- 480

  Fly   313 IDETIGVSGAEEKRSEIFIYNVGAEDNGTFSCVGQNIAGTTFSNYTLRV 361
                   ||    ...:.|:||..||:|.::||.||..|......||||
 Frog   481 -------SG----EGSLQIFNVQVEDSGRYTCVAQNSEGADTKVATLRV 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kek2	NP_523551.1	LRR	<34..>204	CDD:443914	62/320 (19%)
		leucine-rich repeat	34..52	CDD:275380	5/23 (22%)
		leucine-rich repeat	54..79	CDD:275380	8/69 (12%)
		leucine-rich repeat	80..103	CDD:275380	11/22 (50%)
		leucine-rich repeat	104..127	CDD:275380	8/94 (9%)
		leucine-rich repeat	128..151	CDD:275380	9/47 (19%)
		leucine-rich repeat	152..175	CDD:275380	8/23 (35%)
		leucine-rich repeat	176..198	CDD:275380	9/23 (39%)
		LRRCT	207..256	CDD:214507	15/55 (27%)
		Ig_3	258..348	CDD:464046	25/92 (27%)
lrrn1	XP_002938357.1	LRRNT	33..76	CDD:214470	10/41 (24%)
		leucine-rich repeat	75..97	CDD:275378	5/21 (24%)
		LRR	<76..>323	CDD:443914	41/246 (17%)
		leucine-rich repeat	98..121	CDD:275380	0/22 (0%)
		leucine-rich repeat	122..145	CDD:275380	3/22 (14%)
		leucine-rich repeat	146..169	CDD:275380	11/22 (50%)
		leucine-rich repeat	170..193	CDD:275380	3/22 (14%)
		leucine-rich repeat	194..217	CDD:275380	0/22 (0%)
		leucine-rich repeat	218..241	CDD:275380	0/22 (0%)
		leucine-rich repeat	242..265	CDD:275380	5/22 (23%)
		leucine-rich repeat	266..289	CDD:275380	8/22 (36%)
		leucine-rich repeat	290..314	CDD:275380	1/23 (4%)
		LRR_8	313..374	CDD:404697	23/61 (38%)
		leucine-rich repeat	315..336	CDD:275380	8/20 (40%)
		leucine-rich repeat	340..363	CDD:275378	9/23 (39%)
		leucine-rich repeat	364..376	CDD:275378	6/11 (55%)
		LRRCT	372..418	CDD:214507	14/49 (29%)
		I-set	431..518	CDD:400151	28/100 (28%)
		Ig strand B	445..449	CDD:409353	1/3 (33%)
		Ig strand C	458..467	CDD:409353	1/8 (13%)
		Ig strand E	484..488	CDD:409353	0/3 (0%)
		Ig strand F	498..503	CDD:409353	1/4 (25%)
		FN3	538..602	CDD:473895