DRSC/TRiP Functional Genomics Resources

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Protein Alignment kek2 and flrt1

DIOPT Version :9

Sequence 1:NP_523551.1 Gene:kek2 / 34582 FlyBaseID:FBgn0015400 Length:894 Species:Drosophila melanogaster
Sequence 2:XP_017948905.2 Gene:flrt1 / 100486965 XenbaseID:XB-GENE-495403 Length:679 Species:Xenopus tropicalis


Alignment Length:493 Identity:110/493 - (22%)
Similarity:172/493 - (34%) Gaps:154/493 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly    43 LSNLPEGMDPGTQVLNFSGNALQVLQSERFLRMDLLNLQKIYLSRNQLI--RIHEKAFRGLTNLV 105
            ||::|.|:....:.|....|.:..:....|  ..|.||:::.|..|.|.  ||.:..|..|.||.
 Frog   196 LSSIPNGLPHTLEELRLDDNRISTIPLHAF--KGLNNLRRLVLDGNLLANQRIADDTFSRLQNLT 258

  Fly   106 ELDLSENALQ----NVPSETFQDYSSLMRLSLSGNPIRELKTSAFRHLSFLTTLELSNCQVERIE 166
            ||.|..|:|.    |:||      :.|.:|.|..|.|..:..|:...:..|..|:||:..:..:.
 Frog   259 ELSLVRNSLAAPPVNLPS------THLQKLYLQDNAITHIPYSSLSKMRQLQRLDLSSNNLTALP 317

  Fly   167 NEAFVGMDNLEWLRLDGNRIGFIQGTHILPKSLHGISLHSNRWNCDCRLLDIHFW------LVNY 225
            ...|..::||..|                       .|.:|.|.|.|.|:.:..|      :||.
 Frog   318 RGLFDDLENLSQL-----------------------LLRNNPWFCGCNLMWLRDWVKARAAVVNV 359

  Fly   226 NTPLAEEPKCMEPARLKGQVIKSLQREQLACLPEVSPQSS------------YTEVSEGRNMSIT 278
            ...:     |..|.:::|..||.:..|...|. |..|||:            .|..::|...::.
 Frog   360 RGLM-----CQGPEKVRGMAIKDITHELDECF-EG
GPQSNSASARATPGSPIITTPAQGSLFTLK 418

  Fly   279 CLVRAIPEP--------------KVLWLFNGQVMSNDSLMDNLHMYY------------------ 311
            .....|..|              |.| :.|.:.::.||:......::                  
 Frog   419 SKRPRIQLPDSNVDYPMETGTSTKAL-VINVKPLTADSIRITWKAFHPASSFRLSWLRLGHSPAV 482

  Fly   312 -YIDETIGVSG--------AEEKRSEIFIYNVGAEDNGTFSCVGQNIAGTTFSNYTLRVIIKEPP 367
             .|.||: |.|        |.|.||...|..|..:...|:                   :..|.|
 Frog   483 GSITETL-VQGDKTEYLLTALEPRSTYIICMVTMDTGNTY-------------------LADESP 527

  Fly   368 V-----VNEVSFPRDYMN----------YIVASSAGGGI----IFVVL--LCTIVVKCKK--TSE 409
            |     ..:|..|...:|          ..:|...||.:    :|::|  :|..|.:..:  |.|
 Frog   528 VCAKAETADVYGPTTTLNREQNADPLAGLPLAGIIGGAVTLVFLFLILASICWYVHRAGQLLTHE 592

  Fly   410 PA---KQRKKCDQVTSIAGGT--DSSTGSTQDTGMGMM 442
            .|   ..|||.|.|.|   ||  |:|....:..|:.|:
 Frog   593 RAYSRGSRKKDDYVES---GTKKDNSILEIRGPGLQML 627

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
kek2NP_523551.1 leucine-rich repeat 34..52 CDD:275380 4/8 (50%)
leucine-rich repeat 54..79 CDD:275380 4/24 (17%)
LRR_8 79..138 CDD:290566 23/64 (36%)
LRR_RI <80..187 CDD:238064 32/112 (29%)
leucine-rich repeat 80..103 CDD:275380 8/24 (33%)
leucine-rich repeat 104..127 CDD:275380 9/26 (35%)
LRR_8 126..186 CDD:290566 14/59 (24%)
leucine-rich repeat 128..151 CDD:275380 6/22 (27%)
leucine-rich repeat 152..175 CDD:275380 5/22 (23%)
leucine-rich repeat 176..198 CDD:275380 2/21 (10%)
TPKR_C2 207..256 CDD:301599 14/54 (26%)
I-set 258..361 CDD:254352 25/155 (16%)
Ig_2 263..361 CDD:290606 23/150 (15%)
flrt1XP_017948905.2 PRK15370 <65..>388 CDD:185268 57/228 (25%)
leucine-rich repeat 92..114 CDD:275378
leucine-rich repeat 115..135 CDD:275380
leucine-rich repeat 136..159 CDD:275380
leucine-rich repeat 160..185 CDD:275380
leucine-rich repeat 186..206 CDD:275380 4/9 (44%)
leucine-rich repeat 207..230 CDD:275380 4/24 (17%)
leucine-rich repeat 231..256 CDD:275380 8/24 (33%)
leucine-rich repeat 257..278 CDD:275380 9/26 (35%)
leucine-rich repeat 279..302 CDD:275380 6/22 (27%)
leucine-rich repeat 303..326 CDD:275380 5/22 (23%)
FN3 446..510 CDD:214495 12/64 (19%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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