Protein Alignment spag4 and MPS3

DIOPT Version :10

• Sequence 1: NP_609510.2
• Gene: spag4 / 34581
• FlyBaseID: FBgn0032368
• Length: 275
• Species: Drosophila melanogaster
• Sequence 2: NP_012515.4
• Gene: MPS3 / 853434
• SGDID: S000003556
• Length: 682
• Species: Saccharomyces cerevisiae
• Alignment Length: 291
• Identity: 46/291 - (15%)
• Similarity: 100/291 - (34%)
• Gaps: 95/291 - (32%)

  Fly    47 EPKGVG-SGMCNNR---DVSAYVDTLFKRKIGHLMDDVY---------NLKKQVMSADCSSKSAQ 98
            |..|:| :|...:|   |::.||..:...::.::..|.:         :.|:::.....:....|
Yeast   327 ESPGIGTAGSAESRWEYDLNRYVKEILSNELQYIDKDYFIQEMNRRLQSNKQEIWEEITNRLETQ 391

  Fly    99 STPKPESVALAKPRI--NYAS---EELGARIINVKAHS----------IDGTNIIRSLLGLDFST 148
            ...:.:.|......:  .|:|   :.|..:|.|...|.          :.||.::..|      |
Yeast   392 QQQQQQQVQQDYSNVPQQYSSILMKRLIHQIYNSNQHQWEDDLDFATYVQGTKLLNHL------T 450

  Fly   149 NP---------PVNMIRTGL-----------SPGSCFGFNGSRATVTLHLARTIIVEAITLTHVA 193
            :|         |:.::....           .||..:..   |....|:|.:        ::::.
Yeast   451 SPTWRQGSGVQPIELLTDSKQSSSTYWQCENEPGCSWAI---RFKTPLYLTK--------ISYMH 504

  Fly   194 REMTPDL-CVKSAPKNFDVYGLRSENSK----RELLGQWSYDNAANKRTQSY------------- 240
            ...|.:| .:.|||:...:|...|:..:    :.|..|:.: ...:||.::|
Yeast   505 GRFTNNLHIMNSAPRLISLYVKLSQTKEIKALQTLANQYGF-GQHHKRDRNYIKIAKFEYRLTDS 568

  Fly   241 SVRSDTFF-----------RNLDFSFNSNHG 260
            .:|...:.           |::.|..:.|:|
Yeast   569 RIRQQMYLPPWFIQLKPLVRSIVFQVDENYG 599

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
spag4	NP_609510.2	Sad1_UNC	148..274	CDD:400199	25/162 (15%)
MPS3	NP_012515.4	Sad1_UNC	478..615	CDD:474037	22/134 (16%)