back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Dlg5 and Ush1c

DIOPT Version :9

Sequence 1:	NP_609505.1	Gene:	Dlg5 / 34573	FlyBaseID:	FBgn0032363	Length:	1916	Species:	Drosophila melanogaster
Sequence 2:	NP_710143.2	Gene:	Ush1c / 72088	MGIID:	1919338	Length:	910	Species:	Mus musculus

Alignment Length:	294	Identity:	63/294 - (21%)
Similarity:	112/294 - (38%)	Gaps:	98/294 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly  1290 LRRVTIDK-RDKSLGITIQCNNNGG-----GIFVSTVADKSTAMRAGLQVGDQLLEVCGINMRAA 1348
            |:.|.:|: ..:.||::::    ||     |:|:|.:.....|...||||||:::.:.|.::.:.
Mouse    85 LKEVRLDRLHPEGLGLSVR----GGLEFGCGLFISHLIKGGQADSVGLQVGDEIVRINGYSISSC 145

  Fly  1349 TQEIAANVLRQCGDSFTMLVQYNPEKFPSIEYEGAHNLEPESPINHSGSPTPRNSPRPPARNSLF 1413
            |.|...|::|             .:|..||:            :.|.|               |.
Mouse   146 THEEVINLIR-------------TKKTVSIK------------VRHIG---------------LI 170

  Fly  1414 PLPMQPQAPSTRPGSRAPLSHQSIKDQSFTDSLENQSDISSSQDMPSSAATTTTTTASATSTVYD 1478
            |:...|:              :|:|.|.....:.....:......|.:..|
Mouse   171 PVKSSPE--------------ESLKWQYVDQFVSESGGVRGGLGSPGNRTT-------------- 207

  Fly  1479 EEPKPSLPPPPASVPAETLRYVTLHMDKSKNLGIKLFGG--NKVGIYVHDVAVGSPSDHAGIRKG 1541
            :|.|                 |.:.:..|:.||..:..|  .|.||:|..|..||.|...|:..|
Mouse   208 KEKK-----------------VFISLVGSRGLGCSISSGPIQKPGIFVSHVKPGSLSAEVGLETG 255

  Fly  1542 DQILEYNGVDLSGVTAEQAANEISKLTDTVTMLV 1575
            |||:|.||:|.:.:..::|.| :.|.:.::|:.:
Mouse   256 DQIVEVNGIDFTNLDHKEAVN-VLKSSRSLTISI 288

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.