DRSC/TRiP Functional Genomics Resources

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Protein Alignment Dlg5 and Pdzk1

DIOPT Version :9

Sequence 1:NP_609505.1 Gene:Dlg5 / 34573 FlyBaseID:FBgn0032363 Length:1916 Species:Drosophila melanogaster
Sequence 2:NP_113900.1 Gene:Pdzk1 / 65144 RGDID:70924 Length:523 Species:Rattus norvegicus


Alignment Length:383 Identity:86/383 - (22%)
Similarity:137/383 - (35%) Gaps:88/383 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly  1297 KRDKSLGITIQCNNNGGGIFVSTVADKSTAMRAGLQVGDQLLEVCGINMRAATQEIAANVLRQCG 1361
            |...|.|.:::......|:|::.:..:..||:||:...|.|:||.|.|:..|:.|.....:.:.|
  Rat   140 KEGNSFGFSLKTIQGKKGVFLTDITPQGVAMKAGVLADDHLIEVNGENVENASHEEVVEKVTKSG 204

  Fly  1362 DSFTMLVQYNPEKFPSIEYEGAHNLEPESPINHSGSPTPRNSPRPPARNSLFPLPMQPQAPSTRP 1426
            .....|:                 ::.|:...||...||  ..|..|  ||..||.||:....:.
  Rat   205 SRIMFLL-----------------VDKETARCHSEQKTP--FKRETA--SLKLLPHQPRVVVIKK 248

  Fly  1427 GSR-----------------------APLSHQSIKDQSFTDSLENQS----DISSSQDMPSSAAT 1464
            ||.                       :|.....:|:.....::..:|    |..|..:|..:...
  Rat   249 GSNGYGFYLRAGPEQKGQIIKDIEPGSPAEAAGLKNNDLVVAVNGESVEALDHDSVVEMIRNGGD 313

  Fly  1465 TTT------------TTASATSTVY---DEEPKPSL--PPPPASVPAETLRYVT----------- 1501
            .||            :.|..:..:|   .|.|..|:  .|.|.|.|.|.....|           
  Rat   314 QTTLLVLDKEADRIYSLARFSPLLYCQSQELPNGSVKEAPAPISAPLEAPGSATTEDVGDHKPKL 378

  Fly  1502 ---LHMDKSKNLGIKLFGGNKVGIYVHDVAVGSPSDHAGIRKGDQILEYNGVDLSGVTAEQAANE 1563
               :..|.|....:....| :.|.:|.:|..|.|:|.||:...|.|:|.||.::.....::....
  Rat   379 CRLIKEDDSYGFHLNAIRG-QPGSFVKEVQQGGPADKAGLENEDIIIEVNGENVQDEPYDRVVER 442

  Fly  1564 ISKLTDTVTMLVQNKL-HTLKQIKDEP-----GDSFYIRVGFDRTGELNEDDLRFVKD 1615
            |....:.||:||..|: ::..|.|..|     .|.  :..|.|..||...|.....||
  Rat   443 IKSSGEHVTLLVCGKVAYSYFQAKKIPILSSLADP--LVAGPDEKGETEHDSAESTKD 498

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Dlg5NP_609505.1 AAA_23 <165..333 CDD:290211
CENP-F_leu_zip 229..360 CDD:287450
DUF1090 <326..408 CDD:284007
PDZ_signaling 439..516 CDD:238492
PDZ_signaling 533..592 CDD:238492
PDZ_signaling 1290..1369 CDD:238492 19/71 (27%)
PDZ_signaling 1497..1576 CDD:238492 21/92 (23%)
SH3_DLG5 1594..1657 CDD:212794 7/22 (32%)
Guanylate_kin 1737..1904 CDD:279019
NK <1773..1905 CDD:302627
Pdzk1NP_113900.1 PDZ_signaling 7..87 CDD:238492
PDZ 132..212 CDD:214570 19/88 (22%)
PDZ_signaling 242..320 CDD:238492 10/77 (13%)
PDZ 375..455 CDD:214570 20/80 (25%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 479..523 7/20 (35%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3528
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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