Protein Alignment Dlg5 and Mpp4

DIOPT Version :9

• Sequence 1: NP_609505.1
• Gene: Dlg5 / 34573
• FlyBaseID: FBgn0032363
• Length: 1916
• Species: Drosophila melanogaster
• Sequence 2: XP_038940071.1
• Gene: Mpp4 / 58808
• RGDID: 620016
• Length: 636
• Species: Rattus norvegicus
• Alignment Length: 515
• Identity: 109/515 - (21%)
• Similarity: 209/515 - (40%)
• Gaps: 107/515 - (20%)

  Fly  1472 ATSTVYDEEPKPSLPPPPASVP--AETLRYVTLHMDKSKNLGIKLFGGNKVG-IYVHDVAVGSPS 1533
            |..||..::.:|.|||.|.::|  .|.:|.|.| :...:.||..:......| |.|..|..|...
  Rat   156 AHDTVAQKDFEPLLPPLPDNIPDSEEAMRTVCL-VKNQQPLGATIKRHEITGDILVARVIHGGLV 219

  Fly  1534 DHAG-IRKGDQILEYNGVDLSGVTAEQAANEISKLTDTVTMLVQNKLHTLKQIKDEPGDS---FY 1594
            :.:| :..||:::|.|||.:.|:..||..:.::....|:       :..:..:...|..|   .|
  Rat   220 ERSGLLYAGDKLVEVNGVPVEGLDPEQVIHILAMSCGTI-------MFKVIPVSAPPVSSQTTVY 277

  Fly  1595 IRVGFDRTGELNED------DLRFVKDEVLYVDNTVFNGTFGLWRAWKLDAMGHRKEC-GIIPSQ 1652
            :|...|...:.:.|      .|.|:|.::|    .:.:.:..||  |:...:.....| |:|||.
  Rat   278 VRAMIDYWPQEDPDIPCMDAGLPFLKGDIL----QIVDQSDALW--WQARKISDLAICAGLIPSN 336

  Fly  1653 MKVEEELRS------GEVVDCDTGTARRGSTSARRSF-----------FRRKKNQRSSSRDS--T 1698
            ..::.:.|.      .:...|      ..||.::..|           |||  :.|...|.|  :
  Rat   337 HLLKRKQREFWWSQPYQPHTC------LKSTRSKEEFVGDGQQFFIAGFRR--SMRLCRRKSHFS 393

  Fly  1699 EIASFSNTQLSFFPDLGLLNDDGGALSYQRVELLDSPIRRPVLIIGPLSECLMVRLTIDFSNLFK 1763
            ::.:......|.:..:|...::  .:.||| :..|.  .|.::::||..        :..:.|.:
  Rat   394 QLHANMRCTCSCYSAVGAPYEE--VVRYQR-QPADK--HRLIVLVGPSG--------VGVNELRR 445

  Fly  1764 LCEVTAMDCSQEAMEEGLK--------------------ENIFVDYRR------RGNKFECTTVE 1802
            ........|.|.|:....:                    |::...:|.      :|:.:. |:|.
  Rat   446 QLIGCNPSCFQSAVPHTTRSPKSYEMDGREYHYVSRETFESLMYGHRMLEFGEYKGHLYG-TSVN 509

  Fly  1803 AISNACKNDRRHCILDVSISAVERLQRLQIYPIVLLLRFKSAKQIRD-------IRDFGTD-KIS 1859
            |:. |..::.:.|::|:....::..:..::.|.|:.::..|...:|.       |.|:..| |..
  Rat   510 AVL-AVLDEGKICVMDLEPQDIQLARTRELKPYVIFIKPPSMSSMRHSRRNAKIITDYFVDMKFK 573

  Fly  1860 AKAAKEMYERAMKLETDYKQYISAVIPGVSIKHMCTQIKDAVDKEQDKLLWVP---VSSG 1916
            .:..:||.|.|.|:|:.:.|:...||...:::....|:..|:.|.:::|.|||   ||.|
  Rat   574 DEDLQEMEELAQKMESQFGQFFDHVIVNDNLQDARAQLLSAIQKAEEELQWVPEAWVSPG 633

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dlg5	NP_609505.1	AAA_23	<165..333	CDD:290211
		CENP-F_leu_zip	229..360	CDD:287450
		DUF1090	<326..408	CDD:284007
		PDZ_signaling	439..516	CDD:238492
		PDZ_signaling	533..592	CDD:238492
		PDZ_signaling	1290..1369	CDD:238492
		PDZ_signaling	1497..1576	CDD:238492	21/80 (26%)
		SH3_DLG5	1594..1657	CDD:212794	16/69 (23%)
		Guanylate_kin	1737..1904	CDD:279019	35/200 (18%)
		NK	<1773..1905	CDD:302627	31/165 (19%)
Mpp4	XP_038940071.1	L27	<79..114	CDD:197794
		L27	124..171	CDD:197794	5/14 (36%)
		PDZ_signaling	184..263	CDD:238492	21/86 (24%)
		SH3_MPP4	277..337	CDD:212967	16/65 (25%)
		Guanylate_kin	428..618	CDD:395500	35/199 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0194
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810