DRSC/TRiP Functional Genomics Resources

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Protein Alignment Dlg5 and slc9a3r1

DIOPT Version :9

Sequence 1:NP_609505.1 Gene:Dlg5 / 34573 FlyBaseID:FBgn0032363 Length:1916 Species:Drosophila melanogaster
Sequence 2:NP_001006751.1 Gene:slc9a3r1 / 448423 XenbaseID:XB-GENE-487362 Length:320 Species:Xenopus tropicalis


Alignment Length:380 Identity:68/380 - (17%)
Similarity:110/380 - (28%) Gaps:166/380 - (43%)


- Green bases have known domain annotations that are detailed below.


  Fly  1291 RRVTIDKRDKSLGITIQCNNNGGGIFVSTVADKSTAMRAGLQVGDQLLEVCGINMRAATQEIAAN 1355
            |...::|.|...|..:.......|.:|..|...|.|.:|||:.||:|:.|||.::|....:...:
 Frog     5 RVCVLEKGDSGYGFHLHSEKTRPGQYVRLVEPGSAAEKAGLRAGDRLIRVCGEDVRELGHQQVVS 69

  Fly  1356 VLRQCGDSFTMLVQYNPEKFPSIEYEGAHNLEPESPINHSGS----PTPRNSPRPPARNSLFPLP 1416
            .:|...:..|:.||       .:|.|.|    |.||...:.:    |||          .|....
 Frog    70 KIRAATEKLTLEVQ-------GVEEEVA----PSSPKEENKATEKQPTP----------VLDRKE 113

  Fly  1417 MQPQAPSTRPGSRAPLSHQSIKDQSFTDSLENQSDISSSQDMPSSAATTTTTTASATSTVYDEEP 1481
            ::|:..:.:.|                               ||...                  
 Frog   114 LRPRLCTIKKG-------------------------------PSGFG------------------ 129

  Fly  1482 KPSLPPPPASVPAETLRYVTLHMDKSKNLGIKLFGGNKVGIYVHDVAVGSPSDHAGIRKGDQILE 1546
                              ..||.||.           ..|.:|..|...||::.||:...|:|:|
 Frog   130 ------------------FNLHSDKV-----------HPGQFVRAVDPDSPAELAGLLPKDRIVE 165

  Fly  1547 YNGVDLSGVTAEQAANEISKLTDTVTMLVQNKLHTLKQIKDEPGDSFYIRVGFDRTGELNEDDLR 1611
            .||:::.|.........|....|..::||          .|...||::                 
 Frog   166 VNGLNVIGKQHGDVVAAIKAGGDETSLLV----------LDPEADSYF----------------- 203

  Fly  1612 FVKDEVLYVDNTVFNGTFGLWRAWKLDAMGHRKECGIIPSQM----KVEEELRSG 1662
                                            |||.::|.:.    .:.|:|.:|
 Frog   204 --------------------------------KECNVVPGKQHLTGPLPEKLANG 226

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Dlg5NP_609505.1 AAA_23 <165..333 CDD:290211
CENP-F_leu_zip 229..360 CDD:287450
DUF1090 <326..408 CDD:284007
PDZ_signaling 439..516 CDD:238492
PDZ_signaling 533..592 CDD:238492
PDZ_signaling 1290..1369 CDD:238492 21/77 (27%)
PDZ_signaling 1497..1576 CDD:238492 20/78 (26%)
SH3_DLG5 1594..1657 CDD:212794 4/66 (6%)
Guanylate_kin 1737..1904 CDD:279019
NK <1773..1905 CDD:302627
slc9a3r1NP_001006751.1 PDZ_signaling 4..83 CDD:238492 21/77 (27%)
PDZ_signaling 116..195 CDD:238492 25/166 (15%)
EBP50_C 199..320 CDD:370238 9/77 (12%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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