DRSC/TRiP Functional Genomics Resources

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Protein Alignment Dlg5 and guk1b

DIOPT Version :9

Sequence 1:NP_609505.1 Gene:Dlg5 / 34573 FlyBaseID:FBgn0032363 Length:1916 Species:Drosophila melanogaster
Sequence 2:NP_957018.1 Gene:guk1b / 393697 ZFINID:ZDB-GENE-020916-1 Length:223 Species:Danio rerio


Alignment Length:231 Identity:46/231 - (19%)
Similarity:88/231 - (38%) Gaps:77/231 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly  1738 RPVLIIGPL---SECLMVRLTIDFSNLF------------------------------------- 1762
            |||::.||.   ...|:.||..::..:|                                     
Zfish     5 RPVVLSGPSGAGKSTLLKRLMKEYEGVFGFSVSHTTRNPRPGEEDGKGLNCLPMLLGATLLPVAD 69

  Fly  1763 KLCEVTAMD---CSQEAMEEGLKENIFVDYRRRGNKFECTTVEAISNACKNDRRHCILDVSISAV 1824
            .|..||:.|   .::|.|:||:.::.|::..........|:..:|.:. :.....|||||.|..|
Zfish    70 VLSSVTSEDYHFVTKEKMQEGIDKDEFIENAEFSGNMYGTSKSSIEDV-QAQNLICILDVDIQGV 133

  Fly  1825 ERLQRLQIYPIVLLLRFKS----AKQIRDIRDFGTD----------KISAKAAKE--MYERAM-- 1871
            ..:::..:.||.:.::..|    .|::|| |...|:          :|..:.:||  :::..:  
Zfish   134 RNIKKTDLNPIYISIQPPSMEILEKRLRD-RQTETEDSLQKRLEAARIDMELSKEPGVFDIVIVN 197

  Fly  1872 -KLETDYKQYISAVIPGVSIKHMCTQIKDAVDKEQD 1906
             .||..|::..|.:|             :.::|.||
Zfish   198 DDLEEAYEKLKSVLI-------------EEIEKVQD 220

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Dlg5NP_609505.1 AAA_23 <165..333 CDD:290211
CENP-F_leu_zip 229..360 CDD:287450
DUF1090 <326..408 CDD:284007
PDZ_signaling 439..516 CDD:238492
PDZ_signaling 533..592 CDD:238492
PDZ_signaling 1290..1369 CDD:238492
PDZ_signaling 1497..1576 CDD:238492
SH3_DLG5 1594..1657 CDD:212794
Guanylate_kin 1737..1904 CDD:279019 43/227 (19%)
NK <1773..1905 CDD:302627 31/150 (21%)
guk1bNP_957018.1 Gmk 1..219 CDD:223272 44/228 (19%)
guanyl_kin 5..213 CDD:213788 43/222 (19%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0194
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.900

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