Protein Alignment Dlg5 and mpp1

DIOPT Version :9

• Sequence 1: NP_609505.1
• Gene: Dlg5 / 34573
• FlyBaseID: FBgn0032363
• Length: 1916
• Species: Drosophila melanogaster
• Sequence 2: NP_999857.1
• Gene: mpp1 / 325542
• ZFINID: ZDB-GENE-031113-4
• Length: 468
• Species: Danio rerio
• Alignment Length: 520
• Identity: 106/520 - (20%)
• Similarity: 193/520 - (37%)
• Gaps: 114/520 - (21%)

  Fly  1452 ISSSQDMPSSAATTTTTTASATSTVYDEEPKPSLPPPPASV-----------------------P 1493
            ::|:::.|:.......:..:|.|.:|.|:...:.|....:.                       .
Zfish     3 LNSNKNEPAVILERVNSARTALSDLYLEQLLQNKPKSEKAAMQTYECKGQEVFSNGSAGHMNGRD 67

  Fly  1494 AETLRYVTLHMDKSKNLGIKLFGGNKVGIYVHDVAVGSPSDHAG-IRKGDQILEYNGVDLSGVTA 1557
            |..:|.|....:.|:.||:.|....|....|..:..|......| :.:||:|.|.||..:|
Zfish    68 ATRMREVAFEKNPSEPLGVTLKLNEKQRCTVARILHGGMIHRQGSLHEGDEIAEINGKSVS---- 128

  Fly  1558 EQAANEISK-LTDTVTMLVQNKLHTLKQIKDEPGD----SFYIRVGFD---RTGEL---NEDDLR 1611
            .|:.:::.| |.||      |.:.|||.|.::...    ..|:|..||   ...||   .|..|:
Zfish   129 NQSVDQLQKILKDT------NGVVTLKIISNQQSRPMACEMYMRAQFDYDPAKDELIPCKEAGLK 187

  Fly  1612 FVKDEVLYVDNTVFNGTFGLWRAWKLDAMGHRKECGIIPSQMKVEEELRSGEVVDCDTGTARRGS 1676
            |...::::    :.|.....|...|:|: ......|:|||     .||:...|......|...|.
Zfish   188 FQTGDIIH----IINKKDPNWWQGKVDS-SSTDFAGLIPS-----PELQEWRVASKSKATREAGQ 242

  Fly  1677 TSARRSFFRRKKNQRSSSRDSTEIASFSNTQLSFFPDLGLLNDDGGALSYQRVELLDSPIRRPVL 1741
            :.   |.|.:||..:..     .:|..|    |.|..|.:       :||:.|..|.:..|:.::
Zfish   243 SC---SPFGKKKKCKDK-----YLAKHS----SIFDQLDV-------ISYEEVVRLPAFNRKTLV 288

  Fly  1742 IIGPLSECLMVRLTIDFSNLFKLCEVTAMDC--------------------SQEAMEEGLKENIF 1786
            :||...   :.|..|..|.|.|..|..|...                    |.:.|.:|:..|..
Zfish   289 LIGAHG---VGRSLIKNSLLSKYPEKFAYPAPHTTRPQKKDEENGKEYYFISNDEMTKGIVGNKL 350

  Fly  1787 VDY-RRRGNKFECTTVEAISNACKNDRRHCILDVSISAVERLQRLQIYPIVLLLR-FKSAKQIRD 1849
            ::| ..:|:.|. |.:|.| :......:..:|||....::.|:..:..|:|:.:. ..:..|...
Zfish   351 LEYGSYQGHMFG-TKIETI-HKIHEQGKIAVLDVEPQTLKVLRTAEFAPLVIFIAPTNTGNQSEA 413

  Fly  1850 IRDFGTDKISAKAAKEMYERAMKLETDYKQYISAVIPGVSIKHMCTQIKDAVDKEQDKLLWVPVS 1914
            :::...:..|..||             ::.:...::....:......::||:::......|||:|
Zfish   414 VQNIQKESDSLLAA-------------HRHFFDEILVNNDVDESVKGVEDAIERASSSPQWVPIS 465

  Fly  1915  1914
            Zfish   466  465

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dlg5	NP_609505.1	AAA_23	<165..333	CDD:290211
		CENP-F_leu_zip	229..360	CDD:287450
		DUF1090	<326..408	CDD:284007
		PDZ_signaling	439..516	CDD:238492
		PDZ_signaling	533..592	CDD:238492
		PDZ_signaling	1290..1369	CDD:238492
		PDZ_signaling	1497..1576	CDD:238492	22/80 (28%)
		SH3_DLG5	1594..1657	CDD:212794	17/68 (25%)
		Guanylate_kin	1737..1904	CDD:279019	32/188 (17%)
		NK	<1773..1905	CDD:302627	22/133 (17%)
mpp1	NP_999857.1	PDZ	73..151	CDD:278991	25/87 (29%)
		SH3_MPP1	164..225	CDD:213013	17/70 (24%)
		Guanylate_kin	284..453	CDD:279019	32/186 (17%)
		GuKc	293..453	CDD:214504	29/177 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910