Protein Alignment Dlg5 and Gopc

DIOPT Version :9

• Sequence 1: NP_609505.1
• Gene: Dlg5 / 34573
• FlyBaseID: FBgn0032363
• Length: 1916
• Species: Drosophila melanogaster
• Sequence 2: NP_001101101.2
• Gene: Gopc / 309774
• RGDID: 1309512
• Length: 463
• Species: Rattus norvegicus
• Alignment Length: 574
• Identity: 106/574 - (18%)
• Similarity: 198/574 - (34%)
• Gaps: 200/574 - (34%)

  Fly   157 VGSGNPYYFGKTQGCDG-SCSEKLAE--LKKERNMVAVEREKYKKSYI-------ELEKDRNYYR 211
            :.:|.|...|...|..| ||...::.  :...|.:..:|:| :.|:::       |::.|:....
  Rat     1 MSAGGPCPAGAGSGPGGASCPVGVSPGGVSMFRWLEVLEKE-FDKAFVDVDLLLGEIDPDQADIT 64

  Fly   212 ERGDENQKLKVLLSQESKNVLSLTEELNQLLSEKDNVLQEHQKMSDDLVLANKEIERLKKDEQLA 276
            ..|  .||:           .||:....||..:...|.|.:.|:...||....|:...:.::.:.
  Rat    65 YEG--RQKM-----------TSLSSCFAQLCHKAQTVSQINHKLEAQLVDLRSELTETQAEKVVL 116

  Fly   277 RAEI--KVLQLANADLK---------KRDLLKSRDSSWSKEFPSGKELENSK-----------EL 319
            ..|:  ::|||.:..|:         ....:|::.|..|.| ...:|||.:|           |:
  Rat   117 EKEVHDQLLQLHSTQLQLHAKTGQSVDSGAIKAKLSVHSME-DLERELEANKTEKVKEARLEAEV 180

  Fly   320 EKLRK---SLEKALSEVERSSQDAEEAKRVRDWAISQREKIVQ--ERDSVKTLCDKMRHE----- 374
            :.|||   :|.:.::.::.....|..|.:..|..::.|.:.:|  .||......||:.::
  Rat   181 KLLRKENEALRRHIAVLQAEVYGARLAAKYLDKELAGRVQQIQLLGRDMKGPAHDKLWNQLEAEI 245

  Fly   375 ---RDKAISDSLMAIRDSEKIKK--------QKDEAQK--------KIDLLKEQMEQQERQNLDS 420
               |.|.:   :.|.|..:.:|:        .:|..:|        |:.||||     :.:.|..
  Rat   246 HLHRHKTV---IRACRGRQDLKRPMQAPPGHDQDSLKKSQGVGPIRKVLLLKE-----DHEGLGI 302

  Fly   421 NASGSRRSFRPSSYEGEDLLEVELSGYEHTSDLGIILDDSNKRKLVCGVTSSSPA--CGKLKIND 483
            :.:|                     |.||    |:.:       |:..:....||  ||.|.:.|
  Rat   303 SITG---------------------GKEH----GVPI-------LISEIHPGQPADRCGGLHVGD 335

  Fly   484 VICKVNNLDCQSLSKRMVLDEIRACAPRSLLLVSRTRHSKRHAYSVQLKTRDRDCPHGLQLDMGV 548
            .:..||.::.:.                       |:|.:    :|.:.::.|
  Rat   336 AVLAVNGVNLRD-----------------------TKHKE----AVTILSQQR------------ 361

  Fly   549 FIAKIEQNSLAFYEPELDVGDRVLSINNKSMDSVQSIEEVMQLMNDPRSDGLNLFALKYVQDQLP 613
              .:|| ..:.:..||:|..|             :::|     ..|.......|:.     |:|.
  Rat   362 --GEIE-FEVVYVAPEVDSDD-------------ENVE-----YEDESGHRYRLYL-----DELE 400

  Fly   614 PGMTTSSAQTDSIDSMQ-------------HVSSAGGGGGSGPSSAT----KHP 650
            .|..:.::..||...|:             |.:...|..|..|...|    .||
  Rat   401 GGGNSGASCKDSSGEMKVLQGYNKKTVRDAHENGDVGASGESPLDDTAVRAAHP 454

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dlg5	NP_609505.1	AAA_23	<165..333	CDD:290211	42/202 (21%)
		CENP-F_leu_zip	229..360	CDD:287450	33/157 (21%)
		DUF1090	<326..408	CDD:284007	20/107 (19%)
		PDZ_signaling	439..516	CDD:238492	13/78 (17%)
		PDZ_signaling	533..592	CDD:238492	8/58 (14%)
		PDZ_signaling	1290..1369	CDD:238492
		PDZ_signaling	1497..1576	CDD:238492
		SH3_DLG5	1594..1657	CDD:212794
		Guanylate_kin	1737..1904	CDD:279019
		NK	<1773..1905	CDD:302627
Gopc	NP_001101101.2	SMC_prok_B	<35..>215	CDD:274008	39/194 (20%)
		PDZ_signaling	287..369	CDD:238492	26/160 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900