DRSC/TRiP Functional Genomics Resources

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Protein Alignment Dlg5 and Ush1c

DIOPT Version :9

Sequence 1:NP_609505.1 Gene:Dlg5 / 34573 FlyBaseID:FBgn0032363 Length:1916 Species:Drosophila melanogaster
Sequence 2:XP_006229284.1 Gene:Ush1c / 308596 RGDID:1303329 Length:910 Species:Rattus norvegicus


Alignment Length:294 Identity:68/294 - (23%)
Similarity:119/294 - (40%) Gaps:98/294 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly  1290 LRRVTIDK-RDKSLGITIQCNNNGG-----GIFVSTVADKSTAMRAGLQVGDQLLEVCGINMRAA 1348
            |:.|.:|: ..:.||::::    ||     |:|:|.:.....|...||||||:::.:.|.::.:.
  Rat    85 LKEVRLDRLHPEGLGLSVR----GGLEFGCGLFISHLIKGGQADSVGLQVGDEIVRINGYSISSC 145

  Fly  1349 TQEIAANVLRQCGDSFTMLVQYNPEKFPSIEYEGAHNLEPESPINHSGSPTPRNSPRPPARNSLF 1413
            |.|...|::|             .:|..||:            :.|.|               |.
  Rat   146 THEEVINLIR-------------TKKTVSIK------------VRHIG---------------LI 170

  Fly  1414 PLPMQPQAPSTRPGSRAPLSHQSIKDQSFTDSLENQSDISSSQDMPSSAATTTTTTASATSTVYD 1478
            |:...|:         .||..|.: ||..::|...:..:||    |.:..|              
  Rat   171 PVKSSPE---------EPLKWQYV-DQFVSESGGVRGGLSS----PGNRTT-------------- 207

  Fly  1479 EEPKPSLPPPPASVPAETLRYVTLHMDKSKNLGIKLFGG--NKVGIYVHDVAVGSPSDHAGIRKG 1541
            :|.|                 |.:.:..|:.||..:..|  .|.||:|.:|..||.|...|:..|
  Rat   208 KEKK-----------------VFISLVGSRGLGCSISSGPIQKPGIFVSNVKPGSLSAEVGLETG 255

  Fly  1542 DQILEYNGVDLSGVTAEQAANEISKLTDTVTMLV 1575
            |||:|.||:|.:.:..::|.| :.|.:.::|:.:
  Rat   256 DQIVEVNGIDFTNLDHKEAVN-VLKSSRSLTISI 288

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Dlg5NP_609505.1 AAA_23 <165..333 CDD:290211
CENP-F_leu_zip 229..360 CDD:287450
DUF1090 <326..408 CDD:284007
PDZ_signaling 439..516 CDD:238492
PDZ_signaling 533..592 CDD:238492
PDZ_signaling 1290..1369 CDD:238492 22/84 (26%)
PDZ_signaling 1497..1576 CDD:238492 26/81 (32%)
SH3_DLG5 1594..1657 CDD:212794
Guanylate_kin 1737..1904 CDD:279019
NK <1773..1905 CDD:302627
Ush1cXP_006229284.1 harmonin_N 2..80 CDD:259819
PDZ_signaling 85..165 CDD:238492 25/108 (23%)
PDZ_signaling 209..289 CDD:238492 28/98 (29%)
Cgr1 <316..>358 CDD:281823
PDZ_signaling 751..838 CDD:238492
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3528
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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