Protein Alignment Dlg5 and Mpp7

DIOPT Version :9

• Sequence 1: NP_609505.1
• Gene: Dlg5 / 34573
• FlyBaseID: FBgn0032363
• Length: 1916
• Species: Drosophila melanogaster
• Sequence 2: XP_017456050.1
• Gene: Mpp7 / 307035
• RGDID: 1305675
• Length: 601
• Species: Rattus norvegicus
• Alignment Length: 574
• Identity: 123/574 - (21%)
• Similarity: 222/574 - (38%)
• Gaps: 127/574 - (22%)

  Fly  1428 SRAPLSH--QSIKDQSFTDSLENQSDISSSQDM------PSSAATTTTTTASATSTVYDEEPKPS 1484
            |..|:.|  .::.| ...|.|:|:...|..:::      |:..|     ..|...||..:...|.
  Rat    64 SPVPILHGAAALAD-DLADELQNKPPNSEIRELLKLLSKPNVKA-----LLSVHDTVAQKSYDPV 122

  Fly  1485 LPPPPASVPAETLRYVTLHMDKSKN-LGIKLFGGNKVG-IYVHDVAVGSPSDHAG-IRKGDQILE 1546
            |||.|..:..|......:.:.|::. ||..:....:.| |.|..:..|..:|.:| |..||::.|
  Rat   123 LPPMPDDIDDEEDSVKIIRLVKNREPLGATIKKDEQTGAITVARIMRGGAADRSGLIHVGDELRE 187

  Fly  1547 YNGVDLSGVTAEQAANEISKLTDTVTMLVQNKLHTLKQIKDEPGDSFYIRVGF------DRTGEL 1605
            .||:.:.....|:....:|:....:|..:...  |.::|..:.| ..:|:..|      |:....
  Rat   188 VNGIPVEDKRPEEIIQILSQSQGAITFKIIPS--TKEEIPSKEG-KIFIKALFDYDPKEDKAIPC 249

  Fly  1606 NEDDLRFVKDEVLYV----DNTVFNGTFGLWRAWKLDAMGH-RKECGIIPSQ------------- 1652
            .|..|.|.|.::|.:    |.|        |  |:....|. ....|:|||:
  Rat   250 KEAGLSFRKGDILQIMSQDDAT--------W--WQAKHEGDTNPRAGLIPSKHFQERRLALRRPE 304

  Fly  1653 -----MKVEEELRSGEVVDC-----DTGTARRGSTSA------RRSFFRRKKNQRSSSRDSTEIA 1701
                 :|:.......|.|:|     |.|  ..|:.|.      ||| ||..:..:.:::...|..
  Rat   305 IVVQPLKLSNRKSYEETVECEEIKEDAG--HDGNNSGPYIAGFRRS-FRLSRKDKKTNKSMYECK 366

  Fly  1702 SFSNTQLSFFPDLGLLNDDGGALSYQRVELLDSPIRRP-------VLIIGP-------------L 1746
            .......:..|            :|:.|    :|.||.       |:::||             :
  Rat   367 KSEQYDTADVP------------TYEEV----TPYRRQTHDKYRLVVLVGPVGVGLNELKRKLLM 415

  Fly  1747 SECLMVRLTIDFSNLFKLCE----VTAMDCSQEAMEEGLKENIFVDYRRRGNKFECTTVEAI-SN 1806
            |:.....:|:..:...:..:    |..:..|:...|..::.|.|::|....|.:..|::::: |.
  Rat   416 SDTQHYGVTVPHTTRARRSQESDGVEYIFISKHLFETDVQNNKFIEYGEYKNNYYGTSIDSVRSV 480

  Fly  1807 ACKNDRRHCILDVSISAVERLQRLQIYPIVLLLRFKSAKQIRDIR----------DFGTDK-ISA 1860
            ..||  :.|:|||....|:.|:.|:..|.|:.::..|.:::|:.|          |.||.| .:.
  Rat   481 LAKN--KVCLLDVQPHTVKHLRTLEFKPYVIFIKPPSIERLRETRKNAKIISSRDDQGTAKPFTE 543

  Fly  1861 KAAKEMYERAMKLETDYKQYISAVIPGVSIKHMCTQIKDAVDKEQDKLLWVPVS 1914
            :..:||.:.|..:|:.|......:|....:.....::|...||.:....|||||
  Rat   544 EDFQEMIKSAQIMESQYGHLFDKIIINDDLTVAFNELKTTFDKLETDAHWVPVS 597

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dlg5	NP_609505.1	AAA_23	<165..333	CDD:290211
		CENP-F_leu_zip	229..360	CDD:287450
		DUF1090	<326..408	CDD:284007
		PDZ_signaling	439..516	CDD:238492
		PDZ_signaling	533..592	CDD:238492
		PDZ_signaling	1290..1369	CDD:238492
		PDZ_signaling	1497..1576	CDD:238492	18/81 (22%)
		SH3_DLG5	1594..1657	CDD:212794	18/91 (20%)
		Guanylate_kin	1737..1904	CDD:279019	42/202 (21%)
		NK	<1773..1905	CDD:302627	35/143 (24%)
Mpp7	XP_017456050.1	L27	16..68	CDD:197794	1/3 (33%)
		L27	<88..125	CDD:197794	8/41 (20%)
		PDZ_signaling	137..217	CDD:238492	18/79 (23%)
		SH3_MPP7	232..292	CDD:212966	17/69 (25%)
		GuKc	409..588	CDD:214504	38/180 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0194
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810