DRSC/TRiP Functional Genomics Resources

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Protein Alignment Dlg5 and Guk1

DIOPT Version :9

Sequence 1:NP_609505.1 Gene:Dlg5 / 34573 FlyBaseID:FBgn0032363 Length:1916 Species:Drosophila melanogaster
Sequence 2:XP_006246539.1 Gene:Guk1 / 303179 RGDID:1309638 Length:266 Species:Rattus norvegicus


Alignment Length:195 Identity:36/195 - (18%)
Similarity:80/195 - (41%) Gaps:33/195 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly  1738 RPVLIIGPL---SECLMVRLTIDFSNLFKLC-----------EVTAMD---CSQEAMEEGLKENI 1785
            |||::.||.   ...|:.:|..:..::|...           |....|   .::|.|:..:....
  Rat    73 RPVVLSGPSGAGKSTLLKKLFQEHGSVFGFSVSHTTRNPRPGEEDGKDYYFVTREMMQRDIAAGD 137

  Fly  1786 FVDYRRRGNKFECTTVEAISNACKNDRRHCILDVSISAVERLQRLQIYPIVLLLRFKSAKQIRDI 1850
            |:::.........|:.||: .|.:...|.|:|||.:..|..:::..::||.:.::..|    .|:
  Rat   138 FIEHAEFSGNLYGTSKEAV-RAVQAMNRICVLDVDLQGVRSIKKTDLHPIYISVQPPS----MDV 197

  Fly  1851 RDFGTDKISAKAAKEMYERAMKLETDYKQYISAVIPGV--------SIKHMCTQIKDAVDKEQDK 1907
            .:....:.:.:..:.:.:|....:.|.:   |:..||:        ::......:|.|:.:|..|
  Rat   198 LEQRLRQRNTETEESLAKRLAAAQADME---SSKEPGLFDLVIVNDNLDEAYVTLKQALSEEIKK 259

  Fly  1908  1907
              Rat   260  259

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Dlg5NP_609505.1 AAA_23 <165..333 CDD:290211
CENP-F_leu_zip 229..360 CDD:287450
DUF1090 <326..408 CDD:284007
PDZ_signaling 439..516 CDD:238492
PDZ_signaling 533..592 CDD:238492
PDZ_signaling 1290..1369 CDD:238492
PDZ_signaling 1497..1576 CDD:238492
SH3_DLG5 1594..1657 CDD:212794
Guanylate_kin 1737..1904 CDD:279019 34/190 (18%)
NK <1773..1905 CDD:302627 24/139 (17%)
Guk1XP_006246539.1 Guanylate_kin 71..256 CDD:279019 34/190 (18%)
guanyl_kin 73..255 CDD:213788 34/189 (18%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0194
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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