Protein Alignment Dlg5 and magu-3

DIOPT Version :9

• Sequence 1: NP_609505.1
• Gene: Dlg5 / 34573
• FlyBaseID: FBgn0032363
• Length: 1916
• Species: Drosophila melanogaster
• Sequence 2: NP_491260.2
• Gene: magu-3 / 183676
• WormBaseID: WBGene00016841
• Length: 479
• Species: Caenorhabditis elegans
• Alignment Length: 544
• Identity: 84/544 - (15%)
• Similarity: 187/544 - (34%)
• Gaps: 152/544 - (27%)

  Fly  1418 QPQAPSTRPGSRAPLSHQSIKDQSFTDSLENQSDISSSQDMPSSAATT----TTTTASATSTVYD 1478
            :..|.||:....:. |::..|::.....:|.:::|.....:......|    ||.|..|.:.
 Worm    38 EQDADSTKSNGTSS-SNKDGKEKFEQVEIEEKTEIDPKTGLKKRTIVTERVLTTKTFHALAL--- 98

  Fly  1479 EEPKPSLPPPPASVPAETLRYVTLHMD-----------------KSKNLGIKLFGGNKVGIYVHD 1526
            :.|.|::.|...|...:...|..:|..                 :...:.::..||..|...:::
 Worm    99 DGPSPTMTPILRSSGTKNHNYAPIHQSAILLPQYQSRKTTVDAGQLTQVEVEKHGGQLVVTKINE 163

  Fly  1527 VAVGSPSDHAGIRKGDQILEYNGVDLSGVTAEQAANEISKLTDTVTMLVQNKLHTLKQIKDEPGD 1591
                  ..:..::.||.|.:.:|.|:      ....:|..|...|.:.|            ||..
 Worm   164 ------KSNYDLKPGDVITQVDGKDV------YFRADIENLKGKVELTV------------EPAG 204

  Fly  1592 SFYIRVGFDRTGELNEDDLRFVKDEVLYVDNTVFNGTFGLWRAWKLDAMGHRKECGIIPSQMKVE 1656
            .......|.|..:.....:.        ||...      ||                      ::
 Worm   205 IHCAPANFHRVQDTYSSHID--------VDRPC------LW----------------------LD 233

  Fly  1657 EELRSGEVVDCDTGTARRGSTSARRSFFRRKKNQRSSSRDS--TEIASFSN-TQLSFFPDLGLLN 1718
            .|:..|:|:                         :..|:|.  .::....: ||:.:.|.
 Worm   234 LEVNPGDVI-------------------------QILSKDEKWMQVRKLGDLTQVGYLPT----- 268

  Fly  1719 DDGGALSYQRVELLDSPIRRPVLIIGPLS------ECLMVRLTID-FSNLFKLC-------EVTA 1769
                :|:.::|.:|....||.::::|.:.      :.:::||... ||.:..|.       ||..
 Worm   269 ----SLTMEKVSMLCPFGRRTLVLLGAVGTGRRDIKSMLLRLAPHYFSTIVPLTSRAQRPGEVEG 329

  Fly  1770 MD---CSQEAMEEGLKENIFVDYRRRGNKFECTTVEAISNACKNDRRHCILDVSISAVERLQRLQ 1831
            .:   ..:|.:.:.::|...|::....::...|:.:::.|..::.|. |:||.:..:|..|...:
 Worm   330 REYQFVRKEEIYQKIREGGMVEWGELDSQLYGTSADSVRNEIRSGRM-CVLDAAPQSVNYLYNAE 393

  Fly  1832 IYPIVL------LLRFKSAKQIRDIRDFGTDKISAKAAKEMYERAMKLETDYKQYISAVIPGVSI 1890
            ..|.|:      :..|...:.:|     .|.:...: .:.:.:.:.|:..:.|..|...:...:|
 Worm   394 FMPFVVHVVPPPIEEFTQLEAVR-----RTHRTQGQ-LQSICDESAKIGLECKSKIHLTLVNRNI 452

  Fly  1891 KHMCTQIKDAVDKEQDKLLWVPVS 1914
            .....::.|:::..:.:..|||.|
 Worm   453 DVTFKRLVDSLETLRYETQWVPHS 476

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dlg5	NP_609505.1	AAA_23	<165..333	CDD:290211
		CENP-F_leu_zip	229..360	CDD:287450
		DUF1090	<326..408	CDD:284007
		PDZ_signaling	439..516	CDD:238492
		PDZ_signaling	533..592	CDD:238492
		PDZ_signaling	1290..1369	CDD:238492
		PDZ_signaling	1497..1576	CDD:238492	13/95 (14%)
		SH3_DLG5	1594..1657	CDD:212794	6/62 (10%)
		Guanylate_kin	1737..1904	CDD:279019	31/189 (16%)
		NK	<1773..1905	CDD:302627	21/137 (15%)
magu-3	NP_491260.2	PDZ	147..204	CDD:381812	14/80 (18%)
		SH3	218..268	CDD:388381	11/110 (10%)
		Guanylate_kin	282..464	CDD:366206	31/188 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0194
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810