DRSC/TRiP Functional Genomics Resources

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Protein Alignment Dlg5 and smz-2

DIOPT Version :9

Sequence 1:NP_609505.1 Gene:Dlg5 / 34573 FlyBaseID:FBgn0032363 Length:1916 Species:Drosophila melanogaster
Sequence 2:NP_491965.1 Gene:smz-2 / 172415 WormBaseID:WBGene00020661 Length:274 Species:Caenorhabditis elegans


Alignment Length:226 Identity:45/226 - (19%)
Similarity:89/226 - (39%) Gaps:54/226 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly   437 EDLLEVELSGYEHTSDLGIILDDSNKRKLVCGVTSSSPACGKLKINDVICKVNNLDCQSLSKRMV 501
            |.::|:.:. .|....||.   ..|.:.::..:.:.:.:.|||:|.|.:.|||..:|:..:.  .
 Worm     4 EKMIEICID-MEEGEPLGA---TPNDKLVITKIQAGTISEGKLRIGDQVKKVNGQNCKDCND--F 62

  Fly   502 LDEIRACAPRSLLLVSRTRH-------------------SKRHAYSVQLKTRDRDCPHGLQLDMG 547
            ...:|..||.:.:.|:|...                   .:|..|..:|.|... ..:|.:|.:|
 Worm    63 FRALRFAAPCAKITVNRDEKKAEELEARVHIPEDRAKIIQRREGYVYELATLVW-VQNGPKLGLG 126

  Fly   548 -------VFIAKIEQNSLAFYEPELDVGDRVLSINNKSMDSVQSIEEVMQLMNDPRSDGLNLFAL 605
                   |.:::::..|||  |..|.:||.:..::...:.......:::               :
 Worm   127 IKHFQNRVLVSRVDPGSLA--EKCLVLGDHLCDVDGIPVSDKDVARDLL---------------V 174

  Fly   606 KYVQDQLPPGMTTSSAQ-TDSIDSMQHVSSA 635
            |.:|::   |..|...: .||||:.|....|
 Worm   175 KNIQEK---GKVTFVVERPDSIDAKQWAKQA 202

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Dlg5NP_609505.1 AAA_23 <165..333 CDD:290211
CENP-F_leu_zip 229..360 CDD:287450
DUF1090 <326..408 CDD:284007
PDZ_signaling 439..516 CDD:238492 17/76 (22%)
PDZ_signaling 533..592 CDD:238492 12/65 (18%)
PDZ_signaling 1290..1369 CDD:238492
PDZ_signaling 1497..1576 CDD:238492
SH3_DLG5 1594..1657 CDD:212794
Guanylate_kin 1737..1904 CDD:279019
NK <1773..1905 CDD:302627
smz-2NP_491965.1 PDZ_signaling 7..77 CDD:238492 17/75 (23%)
PDZ_signaling 114..188 CDD:238492 15/94 (16%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3528
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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