DRSC/TRiP Functional Genomics Resources

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Protein Alignment Dlg5 and SYNJ2BP-COX16

DIOPT Version :9

Sequence 1:NP_609505.1 Gene:Dlg5 / 34573 FlyBaseID:FBgn0032363 Length:1916 Species:Drosophila melanogaster
Sequence 2:NP_001189476.1 Gene:SYNJ2BP-COX16 / 100529257 HGNCID:48350 Length:191 Species:Homo sapiens


Alignment Length:208 Identity:51/208 - (24%)
Similarity:84/208 - (40%) Gaps:37/208 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly  1279 NVPADFLCPGDLRRVTIDKRDKSLGITI------QCNNNGGGIFVSTVADKSTAMRAG-LQVGDQ 1336
            |...|:|...:  .:.:.:....||..|      |..:|..||:||.:.:...|...| ||.||:
Human     2 NGRVDYLVTEE--EINLTRGPSGLGFNIVGGTDQQYVSNDSGIYVSRIKENGAAALDGRLQEGDK 64

  Fly  1337 LLEVCGINMRAATQEIAANVLRQCGDSFTMLVQYNPEKFPSIEYEGAHNLEPES-PINHSGSPTP 1400
            :|.|.|.:::....:.|.::.|..|.:.::.||              |.|:.:: ||.|.|...|
Human    65 ILSVNGQDLKNLLHQDAVDLFRNAGYAVSLRVQ--------------HRLQVQNGPIGHRGEGDP 115

  Fly  1401 RNSPRPPARNSLFPLP-MQPQAPSTRPGSRAPL--SHQSIKDQSFTDSLEN--------QSDISS 1454
            ...|.......:|.|. |.|:.......::..|  .::.|||..| |..:|        ..|:..
Human   116 SGIPIFMVLVPVFALTMMDPELEKKLKENKISLESEYEKIKDSKF-DDWKNIRGPRPWEDPDLLQ 179

  Fly  1455 SQDMPSSAATTTT 1467
            .:: |.|..|.||
Human   180 GRN-PESLKTKTT 191

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Dlg5NP_609505.1 AAA_23 <165..333 CDD:290211
CENP-F_leu_zip 229..360 CDD:287450
DUF1090 <326..408 CDD:284007
PDZ_signaling 439..516 CDD:238492
PDZ_signaling 533..592 CDD:238492
PDZ_signaling 1290..1369 CDD:238492 21/85 (25%)
PDZ_signaling 1497..1576 CDD:238492
SH3_DLG5 1594..1657 CDD:212794
Guanylate_kin 1737..1904 CDD:279019
NK <1773..1905 CDD:302627
SYNJ2BP-COX16NP_001189476.1 PDZ_signaling 13..97 CDD:238492 21/83 (25%)
DegQ <16..77 CDD:223343 18/60 (30%)
COX16 <133..173 CDD:290843 9/40 (23%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3528
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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