DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cog8 and cog8

DIOPT Version :9

Sequence 1:	NP_609503.2	Gene:	Cog8 / 34571	FlyBaseID:	FBgn0287204	Length:	570	Species:	Drosophila melanogaster
Sequence 2:	NP_595623.2	Gene:	cog8 / 2539796	PomBaseID:	SPBC11B10.03	Length:	378	Species:	Schizosaccharomyces pombe

Alignment Length:	378	Identity:	96/378 - (25%)
Similarity:	166/378 - (43%)	Gaps:	56/378 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 DGVPDNLRGNPELDNYLAKLGTCKVEQLKKEQTRLAEEARTILEQTQDLAISNYRTFITTA---- 81
            |.:.||:   .|:|.::..|......:|:|.:..|..:...::::.|.|...||...:..|
pombe     2 DSIGDNV---TEMDAFVRDLTMKPYAELEKRKAELHAQKLKLVQKRQQLLRDNYNVLVDYARNQD 63

  Fly    82 ------ENSRSIFSEFLRSEQQLDTLVSKLPDLSVQCERFLQDSAELNEQRRLNSITLQKNAQLL 140
                  ||||..|.|.:....||...|.:       .:.||   ..::|..|...:..|...||.
pombe    64 AFYQLLENSRHDFKELVLHTNQLYEPVKR-------SQNFL---TSISEHYRDAKLMHQVQPQLS 118

  Fly   141 EVLELPQLMERCIREGRYEEALELAAYATRLGQHQGHIPVVTSIVRSVEALWHNMLVQLVAQLRT 205
            .:||||:||..||....:.|.||..|.|.||....|...::..::..||.|...:..:|:.||:.
pombe   119 SILELPELMNACIERNYFSETLEFQALAYRLKDRFGTNSIIQELITQVETLVVKLTEKLILQLQK 183

  Fly   206 DLQLPKCLQIVGYLRRMQAFGDNELRLKFLQARDAW---LTSCLEAIPTAD---AQQHLSKTIEI 264
            .|:|...:::|.|||......:.:|:..||..  :|   .||....:|..|   .:.:|.:.|::
pombe   184 PLKLYSLIKVVTYLRVTAKLSEAQLKYVFLYF--SWKQLQTSLRNLVPLLDYNNPELYLRRYIQV 246

  Fly   265 TRINLFNIITQYRAIFPEDE-------GTL----KTQSSLRPLQGVSCNGDRLFQAWLHNKISDF 318
            .|...|:::.||:::|.|..       ||:    .|.:|..|.: :...|   |..:..|.:|.|
pombe   247 IRDRAFSLLFQYQSVFGESSNDRLNAAGTVDIPNSTSTSASPFE-MDPEG---FNNFGQNILSSF 307

  Fly   319 LQTLERD----LQLGVGSVE------TVLGQCMYFGLSFSRVGADFRALMAPI 361
            ::.|:.:    ||..:.:|:      ::|.|..|...|.::||.|....::.|
pombe   308 VRKLQLEICYVLQKFMPNVKDSTSKFSLLLQLYYCNQSLTKVGTDISIPLSKI 360

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cog8	NP_609503.2	Dor1	37..379	CDD:252394	91/362 (25%)
cog8	NP_595623.2	Dor1	15..354	CDD:252394	90/354 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	92	1.000	Domainoid score	I2013
eggNOG	1	0.900	-	-		E1_KOG2069
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	98	1.000	Inparanoid score	I1680
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005159
OrthoInspector	1	1.000	-	-		oto102149
orthoMCL	1	0.900	-	-		OOG6_102872
Panther	1	1.100	-	-	LDO	PTHR21311
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R223
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.890