DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment salm and znf367

DIOPT Version :9

Sequence 1:	NP_723670.2	Gene:	salm / 34569	FlyBaseID:	FBgn0261648	Length:	1365	Species:	Drosophila melanogaster
Sequence 2:	NP_001017726.2	Gene:	znf367 / 550421	ZFINID:	ZDB-GENE-050417-231	Length:	316	Species:	Danio rerio

Alignment Length:	288	Identity:	78/288 - (27%)
Similarity:	109/288 - (37%)	Gaps:	85/288 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   385 GSDLASSIITNH-----DDLPEPNSLDLLQKRAQEVLDSASQGILANSMADDFAFGEKSGEGKGR 444
            ||..||...|:.     |.|..|..|....:|.:...|:..:  |.|.       ||.|..
Zfish    68 GSGAASPTRTSSSPAEADPLSCPEHLKDGIRRGRPRADTVRE--LINE-------GENSTS---- 119

  Fly   445 NEPFFKHRCRYCGKVFGSDSALQIHIRSHTGERPFKCNV--CGSRFTTKGNLKVHFQRHAQKFPH 507
                 :.||..|.:||..:.:||.|.|:||||||:.|:.  ||..|...|.||.|.:.|..:.|.
Zfish   120 -----RIRCNICNRVFPREKSLQAHKRTHTGERPYLCDYPDCGKAFVQSGQLKTHQRLHTGEKPF 179

  Fly   508 V------PMNATPIPEHMDKFHP-PLLDQMSPTDSSPNHSPAPPPLGSAPASFPPAFPGLQNLYR 565
            |      ....|....|..| || ..|.:..||..                      ||
Zfish   180 VCSEKACGSRFTHANRHCAK-HPYARLKREEPTGG----------------------PG------ 215

  Fly   566 PPMEILKSLGA--AAPHQYFPQELPT-DLRKPSPQLDEDEPQVKNEPVEEKDQR----------- 616
                  ||.||  .|..::..:...| :.|.|.|  .:.:||.|: |:|:::|:
Zfish   216 ------KSQGADNKAVAEWLTKYWQTREQRSPVP--GKAKPQNKS-PLEDQEQQDPLDFLPSDEG 271

  Fly   617 EEHEQEMAECSEPEPEPLPLEVRIKEER 644
            ||.||| .|.|.|....:....|::|:|
Zfish   272 EEEEQE-EEKSAPSGGVVTARRRLQEQR 298

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
salm	NP_723670.2	zf-C2H2	451..473	CDD:278523	9/21 (43%)
		C2H2 Zn finger	453..473	CDD:275368	8/19 (42%)
		zf-H2C2_2	465..490	CDD:290200	14/26 (54%)
		C2H2 Zn finger	481..501	CDD:275368	8/21 (38%)
		C2H2 Zn finger	826..846	CDD:275368
		zf-H2C2_2	838..863	CDD:290200
		zf-C2H2_2	854..922	CDD:289522
		C2H2 Zn finger	854..874	CDD:275368
		C2H2 Zn finger	886..906	CDD:275368
		C2H2 Zn finger	1291..1311	CDD:275368
		zf-H2C2_2	1303..1328	CDD:290200
		C2H2 Zn finger	1319..1339	CDD:275368
znf367	NP_001017726.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	61..97		9/28 (32%)
		COG5048	115..>182	CDD:227381	28/75 (37%)
		C2H2 Zn finger	123..143	CDD:275368	8/19 (42%)
		C2H2 Zn finger	151..173	CDD:275368	8/21 (38%)
		C2H2 Zn finger	181..200	CDD:275368	3/19 (16%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	234..294		18/63 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1943
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.030