DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment salm and Zfp367

DIOPT Version :9

Sequence 1:	NP_723670.2	Gene:	salm / 34569	FlyBaseID:	FBgn0261648	Length:	1365	Species:	Drosophila melanogaster
Sequence 2:	NP_780703.1	Gene:	Zfp367 / 238673	MGIID:	2442266	Length:	340	Species:	Mus musculus

Alignment Length:	309	Identity:	77/309 - (24%)
Similarity:	111/309 - (35%)	Gaps:	95/309 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   661 RRTPSPSSE-------HRSPHHHRHSHMGYPPVVQPIQPAALMHPQSSPGSQSHLDHLPTPGQLP 718
            |..|:|.:|       |.||..         .:|..|:......|.||.|...     |.|..:|
Mouse     3 RGAPAPMAEPPPVVFCHDSPKR---------VLVSVIRTTPATPPCSSVGEPE-----PPPPLVP 53

  Fly   719 PR---EDFFAERFPLNFTTAKMLSPEHHSPVRSP--AGGALPPGVPPPPHHHPHHMARSPFFNPI 778
            ..   .||..  :|..:      ....|:...||  |||.:..|:                  |:
Mouse    54 TSPGFSDFMV--YPWRW------GENAHNVTLSPGAAGGVVSAGL------------------PV 92

  Fly   779 KHEMAALLPRPHSNDN----SWENFIEVSNTCETMKLKE---------------LMKNKKISDPN 824
            ..|:..|...|.|:.:    |.....|.:::.::..||:               :.:.:..|...
Mouse    93 AAELPTLRGAPQSSASVAAVSGGEDEEEASSPDSGHLKDGIRRGRPRADTVRDLINEGEHSSSRI 157

  Fly   825 QCVVCDRVLSCKSALQMHYRTHTGERPFKCRI--CGRAFTTKGNLKTHMAVHKIRPPM------- 880
            :|.:|:||...:.:||.|.||||||||:.|..  ||:||...|.||||..:|....|.
Mouse   158 RCNICNRVFPREKSLQAHKRTHTGERPYLCDYPDCGKAFVQSGQLKTHQRLHTGEKPFVCSENGC 222

  Fly   881 --RNFHQCPVCHKKYSNALVLQQHIRLHTGEPTDL-----TPEQIQAAE 922
              |..|....|.|        ..:.||...||||.     :|:...|||
Mouse   223 LSRFTHANRHCPK--------HPYARLKREEPTDALSKHQSPDNKAAAE 263

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
salm	NP_723670.2	zf-C2H2	451..473	CDD:278523
		C2H2 Zn finger	453..473	CDD:275368
		zf-H2C2_2	465..490	CDD:290200
		C2H2 Zn finger	481..501	CDD:275368
		C2H2 Zn finger	826..846	CDD:275368	8/19 (42%)
		zf-H2C2_2	838..863	CDD:290200	16/26 (62%)
		zf-C2H2_2	854..922	CDD:289522	24/83 (29%)
		C2H2 Zn finger	854..874	CDD:275368	10/21 (48%)
		C2H2 Zn finger	886..906	CDD:275368	3/19 (16%)
		C2H2 Zn finger	1291..1311	CDD:275368
		zf-H2C2_2	1303..1328	CDD:290200
		C2H2 Zn finger	1319..1339	CDD:275368
Zfp367	NP_780703.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	101..140		6/38 (16%)
		COG5048	157..>230	CDD:227381	29/72 (40%)
		zf-C2H2	158..179	CDD:278523	8/20 (40%)
		C2H2 Zn finger	159..179	CDD:275368	8/19 (42%)
		zf-H2C2_2	171..198	CDD:290200	16/26 (62%)
		C2H2 Zn finger	187..209	CDD:275368	10/21 (48%)
		zf-H2C2_2	202..228	CDD:290200	7/25 (28%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	280..317
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1943
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030