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Protein Alignment salm and ZNF268

DIOPT Version :9

Sequence 1:	NP_723670.2	Gene:	salm / 34569	FlyBaseID:	FBgn0261648	Length:	1365	Species:	Drosophila melanogaster
Sequence 2:	NP_001159353.1	Gene:	ZNF268 / 10795	HGNCID:	13061	Length:	947	Species:	Homo sapiens

Alignment Length:	958	Identity:	174/958 - (18%)
Similarity:	253/958 - (26%)	Gaps:	430/958 - (44%)

- Green bases have known domain annotations that are detailed below.

  Fly   427 SMADDFAFGEKSGEGKGRNEPFFKHRCRYCGKVFGSDSALQIHIRSHTGERPFKCNVCGSRFTTK 491
            |..|.....:|:..|:   :|:.   |..|||.||..|.|.||.|.||||:|::||.|...|.||
Human   370 SRKDQLVSHQKTHSGQ---KPYV---CNECGKAFGLKSQLIIHERIHTGEKPYECNECQKAFNTK 428

  Fly   492 GNLKVHFQRHAQKFPHVPMNATPIPEHMDKFHPPLLDQMSPTDSSPNHSPAPPPLGSAPASFPPA 556
            .||.||.:.|..:.|:|..:.    .....|...|:                            .
Human   429 SNLMVHQRTHTGEKPYVCSDC----GKAFTFKSQLI----------------------------V 461

  Fly   557 FPGLQNLYRPPMEILKSLGAAAPHQYF-PQELPTDLRKPSPQLDEDEPQVKNE-----------P 609
            ..|:....:|...|....|.:...|.. .|...|.::          |.|.||           .
Human   462 HQGIHTGVKPYGCIQCGKGFSLKSQLIVHQRSHTGMK----------PYVCNECGKAFRSKSYLI 516

  Fly   610 VEEKDQREEHEQEMAECSEPEPEPLPLEVRIKEERVEEQEQVKQEDHRIEPRRTPSPSSEHRSPH 674
            :..:....|...|...|.:        ....|.:.:..| ::...::..|........|......
Human   517 IHTRTHTGEKLHECNNCGK--------AFSFKSQLIIHQ-RIHTGENPYECHECGKAFSRKYQLI 572

  Fly   675 HHRHSHMGYPPV-------VQPIQPAALMHPQSSPGSQSHLDHLPTPGQLPPREDFFAERFPLNF 732
            .|:.:|.|..|.       ...::...::|.::..|                .:.|........|
Human   573 SHQRTHAGEKPYECTDCGKAFGLKSQLIIHQRTHTG----------------EKPFECSECQKAF 621

  Fly   733 TTAKMLSPEHHSPVRSPAGGALPPGVPPPPHHHPHHMARSPFFNPIKHEMAALLPRPHSNDNSWE 797
            .|..                                       |.|.|:......:|:|.:...:
Human   622 NTKS---------------------------------------NLIVHQRTHTGEKPYSCNECGK 647

  Fly   798 NFIEVSNTCETMKLKELMKNKKIS---DPNQCVVCDRVLSCKSALQMHYRTHTGERPFKCRICGR 859
            .|        |.| .:|:.:|.:.   .|..|..|.:..|.||.|.:|.|:|||.:|:.|..||:
Human   648 AF--------TFK-SQLIVHKGVHTGVKPYGCSQCAKTFSLKSQLIVHQRSHTGVKPYGCSECGK 703

  Fly   860 AFTTKGNLKTHMAVHKIRPPMRNFHQCPVCHKKYSNALVLQQHIRLHTGEPTDLTPEQIQAAEIR 924
            ||.:|..|..||..|....|    |:|..|.|.:|....|..|.|:||||
Human   704 AFRSKSYLIIHMRTHTGEKP----HECRECGKSFSFNSQLIVHQRIHTGE--------------- 749

  Fly   925 DPPPSMMPGHFMNPFAAA----AF------------HFGALPGGPGGPPGPNHGAHNGALGSESS 973
                        ||:..:    ||            |.|..|.|..
Human   750 ------------NPYECSECGKAFNRKDQLISHQRTHAGEKPYGCS------------------- 783

  Fly   974 QGDMDDNMDCGEDYDDDVSSE-----HLSNSNLEQEGDRSRSGDDF--KSLLFEQKLRIDATGVV 1031
                    :||:.:    ||:     |:...:.|:..:.:..|..|  ||||.
Human   784 --------ECGKAF----SSKSYLIIHMRTHSGEKPYECNECGKAFIWKSLLI------------ 824

  Fly  1032 NTNPVRPRSSASSHGHSVGSTSAPTSPSVHASSQVIKRSSSPARSEASQGALDLTPRAAPTSSSS 1096
                |..|            |.|..:|  :..||..|..|         |.|.|
Human   825 ----VHER------------THAGVNP--YKCSQCEKSFS---------GKLRL----------- 851

  Fly  1097 SRSPLPKEKPVSPPSLPRSPSGSSHASANILTSPLPPTVGIDCLPPGLQHHLQQQHQHLMQQQAA 1161
                                                               |..|..|..::...
Human   852 ---------------------------------------------------LVHQRMHTREKPYE 865

  Fly  1162 VAAAAAAQHHHHQQMAALHQHQEQLRREAAEAQQKAAAAAAAAAAAAAAQRQTPPQARDQRQEGG 1226
            .:....|...:.|.:  :|                                        ||...|
Human   866 CSECGKAFIRNSQLI--VH----------------------------------------QRTHSG 888

  Fly  1227 PGAGPPPNPLMGARPPFGMFPNLPLFPPATTQNMCNAMNQIAQSVMPAAPFNPLALSGVRGSTTC 1291
                         ..|:|                                              |
Human   889 -------------EKPYG----------------------------------------------C 894

  Fly  1292 GICYKTFPCHSALEIHYRSHTKERPFKCSICDRGFTTKGNLKQHMLTH 1339
            ..|.|||...|.|..|.|:||.|:|.||:.|.:.|..|..|..|..||
Human   895 NECGKTFSQKSILSAHQRTHTGEKPCKCTECGKAFCWKSQLIMHQRTH 942

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.