Protein Alignment salm and znf516

DIOPT Version :10

• Sequence 1: NP_723670.2
• Gene: salm / 34569
• FlyBaseID: FBgn0261648
• Length: 1365
• Species: Drosophila melanogaster
• Sequence 2: NP_001153141.1
• Gene: znf516 / 100003866
• ZFINID: ZDB-GENE-060503-194
• Length: 1084
• Species: Danio rerio
• Alignment Length: 1160
• Identity: 230/1160 - (19%)
• Similarity: 350/1160 - (30%)
• Gaps: 387/1160 - (33%)

  Fly   446 EPFFK-------------HRCRYCGKVFGSDSALQIHIRSHTGERPFKCNVCGSRFTTKGNLKVH 497
            |||.|             |.|..||:.|...|:|..|:|.||||:|:||..|..|...||:||.|
Zfish    12 EPFSKGGHDNPDVKKSRGHTCELCGRSFPFLSSLSQHMRKHTGEKPYKCPHCEHRSAQKGSLKAH 76

  Fly   498 FQRHAQKFPHVPMNATPIPEHMDKFH------PPLLDQ---MSPTDSS-------PNHSPAPPPL 546
            .:.|  |...:..:.....|.||:..      |.  ||   .|||:|:       ..........
Zfish    77 IRSH--KLDGLSQSGGGEEEDMDEEGEKEGGVPE--DQGSCSSPTESTSACNKVVSGEDATKMRK 137

  Fly   547 GSAPASFPPAFPGLQ----NLYRPPMEILKSLGAAAPHQYFPQELPTDLR---KPSPQLDEDEPQ 604
            .|......|...|.|    :|.|      |.|...|..:...|||...||   .|.....||:.|
Zfish   138 KSGKKERIPGESGKQSVQCSLCR------KRLSGQAELEKHMQELHKVLRCELCPYETQQEDQLQ 196

  Fly   605 V---KNEPVEEKDQREE-------------HEQEMAECSEPEPEPLPLEVRIKEERVEEQEQVKQ 653
            .   |:.|.:|:...:|             .|....:|.:...:...|:..:|:.:       ..
Zfish   197 AHVEKDHPSDEESITKEVSTSEETDGILGKGEFPCEQCDQVFTQAWCLKTHMKKHQ-------NS 254

  Fly   654 EDH--RIEPRRTPSP--SSEHRSPHHHR---HSHMGYPPVVQPI--------------------- 690
            .||  ||..||...|  ...|...|:.:   .|:...|..|..:
Zfish   255 MDHGCRICGRRFREPWFLRSHMKTHNTKVKPRSNSYLPATVNEVAQDESNLVNEVCLYELCAKCG 319

  Fly   691 -----QPAALMHPQSSPGSQSHLDHLPTPGQLPPREDFFAERFPLNFTTAKMLSPEHHSPVRSPA 750
                 :.:..:|.|.....:..|.:...      .|:.|......:|.....|.|..:  :.:|:
Zfish   320 NFFHDRKSLQLHEQVHKNIEQPLKNKNC------NENNFPSVTKTSFLQCLNLKPAGN--IENPS 376

  Fly   751 GGALPPGVPPPPHHHPHHMARSPFFNPIKHEMA------ALLPRPHSNDNSWENFIEVSNTCETM 809
            .|.:.              .|.|..:|:....|      ..|.........||..:..::.....
Zfish   377 EGTIG--------------KRIPELDPVSSYQAWQLATRGKLVEVTERSQGWEERLADADVAYDR 427

  Fly   810 KLKELM-----KNKKISDPNQCVVCDR-----VLSC----KSALQMHYRTHTGER---------- 850
            :..|.:     |.||..|....:...:     ...|    .|..:.:....||||
Zfish   428 EKGEYVLLRQDKRKKSLDSTVSIPTKKRRGAVTQGCTPDQHSNGEKNSHVSTGERSPENLSDSEY 492

  Fly   851 -------------PFKCRICGRAFTTKGNLKTHMAVHKIRPPMRNFHQCPVCHKKYSNALVLQQH 902
                         ..:|..||:.|.|:..:..||.:.               |......:.....
Zfish   493 RPTSRPSRKNSQKTSECLECGKGFRTQQQMVIHMLIR---------------HGGLGETIGGNGL 542

  Fly   903 IRLHTGEP---------------------TDLTPEQIQAAEIRDPPPSMMPGHFMNPFAAAAFHF 946
            .|..|..|                     ||..|...:..:.....||.:..|.....:|..
Zfish   543 FRKTTSSPSKTGESAGHFRDQRRAGFLGDTDKKPYTCEHCDFCTSEPSAIAAHIQTHQSAVR--- 604

  Fly   947 GALPGGPGGPPGPNHGAHNGALGSESSQGDMDDNMDCG----------EDYDDDVSSEH-----L 996
                         :.|..:.||.|..||.........|          :.|....:|.|     |
Zfish   605 -------------DWGQRSDALTSSLSQSQTHQTNHTGFPRLRNALLQQPYWPYTTSTHLERAAL 656

  Fly   997 SNSNLEQEGDRSR------SGDDFKSLLFEQKLRID----ATGVVNTNPVR---PRSSASSH--- 1045
            |::.|:.|.::|:      |.|..:|.|....:.:|    .:.::..|.||   |..|.::|
Zfish   657 SDAALKTEEEKSKGLEESSSTDKAESNLLNLSVDVDNKKEVSSILLNNLVRHQCPYCSYATHYPE 721

  Fly  1046 --------GHSVGSTSAPTSPSVHASSQVIKRSSSPARSEASQGALDLTPRAAPTSSSSSRSPLP 1102
                    .|.:.||:                               |.|:.||.:.......|.
Zfish   722 VLWIHQRIAHKIDSTT-------------------------------LVPKWAPKNGLKGPKTLL 755

  Fly  1103 --KEKPVSPPSL-----PRSPSGSSHASANILTSPLPPTVGIDCLPPG------LQHHLQQQHQH 1154
              |.:...||.|     |..|...|:.::       ||    ||.|.|      |...::.....
Zfish   756 DFKRRTGPPPFLEGKDCPSLPQMRSYRTS-------PP----DCSPGGTKKSKPLTSTVESSSSQ 809

  Fly  1155 LMQQQAAVAAAAAAQHHHHQ-------QMA-ALHQ---HQEQLRREAAEAQQ----KAAAAAAAA 1204
            ......|.|..|::....|:       ::| :.|:   ||....|..|..|:    |..:....:
Zfish   810 NKSWHTATAPGASSHSSKHKTSKSRTDELAGSKHKTDIHQNNSSRPMASPQKTGNPKTGSRVVES 874

  Fly  1205 A---------------------AAAAAQRQTPPQARDQRQEGGPGAGPPPNPLMGARPPFGMFPN 1248
            :                     ::.|...|||.::..|.|:....||..|...:|...|
Zfish   875 SLLPQEGLHFMLSSKHNLSDQRSSKAHAPQTPSKSDSQAQDTPSVAGYDPWNRLGLSGP------ 933

  Fly  1249 LPLFPPATTQNMCNAMNQIAQSVMPAAPF----NP---------------------LALSG-VRG 1287
               .|.:.::....|..  |:.|.....|    ||                     ||.|| .:|
Zfish   934 ---SPHSQSKRQSTADG--AEGVTDILSFLKNCNPHDLAALYHHWGYSSAMTEQAGLARSGSQQG 993

  Fly  1288 STTCGICYKTFPCHSALEIHYRSHTKERPFKCSICDRGFTTKGNLKQHMLT-HKI 1341
            ...|.:|.|:|...|....|.||||.||||:|..|....:.|||||.|:.| |::
Zfish   994 EYVCPVCRKSFNQPSHYRTHMRSHTGERPFQCRYCPYSASQKGNLKTHVQTVHRL 1048

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
salm	NP_723670.2	SUF4-like	450..520	CDD:411020	27/82 (33%)
		C2H2 Zn finger	453..474	CDD:411020	8/20 (40%)
		C2H2 Zn finger	453..473	CDD:275368	8/19 (42%)
		C2H2 Zn finger	481..501	CDD:411020	8/19 (42%)
		C2H2 Zn finger	481..501	CDD:275368	8/19 (42%)
		SUF4-like	826..>876	CDD:411020	13/81 (16%)
		C2H2 Zn finger	826..847	CDD:411020	2/29 (7%)
		C2H2 Zn finger	826..846	CDD:275368	2/28 (7%)
		C2H2 Zn finger	854..874	CDD:411020	7/19 (37%)
		C2H2 Zn finger	854..874	CDD:275368	7/19 (37%)
		C2H2 Zn finger	886..906	CDD:275368	2/19 (11%)
		SUF4-like	1291..>1341	CDD:411020	24/50 (48%)
		C2H2 Zn finger	1291..1312	CDD:411020	8/20 (40%)
		C2H2 Zn finger	1291..1311	CDD:275368	7/19 (37%)
		zf-C2H2	1317..1339	CDD:395048	10/22 (45%)
		C2H2 Zn finger	1319..1339	CDD:411020	9/20 (45%)
		C2H2 Zn finger	1319..1339	CDD:275368	9/20 (45%)
znf516	NP_001153141.1	zf-C2H2	30..52	CDD:395048	9/21 (43%)
		C2H2 Zn finger	32..52	CDD:275368	8/19 (42%)
		zf-H2C2_2	44..69	CDD:463886	12/24 (50%)
		C2H2 Zn finger	60..80	CDD:275368	8/19 (42%)
		C2H2 Zn finger	231..251	CDD:275368	3/19 (16%)
		C2H2 Zn finger	259..279	CDD:275368	6/19 (32%)
		zf-C2H2	995..1017	CDD:395048	7/21 (33%)
		C2H2 Zn finger	997..1017	CDD:275368	7/19 (37%)
		zf-H2C2_2	1009..1034	CDD:463886	11/24 (46%)
		C2H2 Zn finger	1025..1046	CDD:275368	9/20 (45%)