DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment salr and YPR015C

DIOPT Version :9

Sequence 1:	NP_001245983.1	Gene:	salr / 34568	FlyBaseID:	FBgn0000287	Length:	1267	Species:	Drosophila melanogaster
Sequence 2:	NP_015340.1	Gene:	YPR015C / 856125	SGDID:	S000006219	Length:	247	Species:	Saccharomyces cerevisiae

Alignment Length:	266	Identity:	65/266 - (24%)
Similarity:	98/266 - (36%)	Gaps:	92/266 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   414 VGQEQHQNQVEEPEEIRQEIPVPQAEDLSKPMVKEKEKSHSPVERVKTPKEVKTDAAL------- 471
            :|....|:..|.....::|:.:|....:          .|:|:    || |: ..|||
Yeast    22 IGGSYAQSSKEVSNTTKREVHLPPCSSI----------MHAPL----TP-EI-NQAALPPPAYHY 70

  Fly   472 -PSS----------EKPEKEISKPVV--------TSSRRNGSVRKRQTSAVS------PP----- 506
             |||          ..|...|..||:        |...|........|:|.|      ||
Yeast    71 APSSLHQTEDPVWRSSPNSIIFSPVIATPQPFPLTFVERQSCCPIYSTAASSYTAQSVPPSMQHF 135

  Fly   507 QEDRERDLVEHLHIAKLVRRSSASRESQPAEYSLAQME------RIIDKSWEDLIEIDKTSETSK 565
            ||:..|               :.|.|    :|||..:.      .::.::..||..|.|     :
Yeast   136 QEENHR---------------AVSNE----QYSLPNVHIGQNPGTLLSQTQTDLDLIQK-----Q 176

  Fly   566 LQQLVDNIENKLTDPNQCIFCQKVMSCRSSLQMHIRTHTGERPFRC--KICGRAFATKGNLKAHM 628
            |:.:|     ||.  .||..|.||.|..|:|:.|...|||:.||:|  :.|.::|..|.|:..|:
Yeast   177 LRAVV-----KLR--KQCPICGKVCSRPSTLRTHYLIHTGDTPFKCTWEHCNKSFNVKSNMLRHL 234

  Fly   629 SIHKIK 634
            ..|:.|
Yeast   235 RTHQKK 240

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
salr	NP_001245983.1	zf-C2H2	321..343	CDD:278523
		C2H2 Zn finger	323..343	CDD:275368
		zf-H2C2_2	335..360	CDD:290200
		C2H2 Zn finger	351..371	CDD:275368
		C2H2 Zn finger	583..603	CDD:275368	8/19 (42%)
		zf-H2C2_2	595..620	CDD:290200	10/26 (38%)
		C2H2 Zn finger	611..631	CDD:275368	6/21 (29%)
		C2H2 Zn finger	643..663	CDD:275368
		lambda-1	1013..>1061	CDD:212564
		zf-C2H2	1040..1062	CDD:278523
		C2H2 Zn finger	1042..1062	CDD:275368
		zf-H2C2_2	1054..1079	CDD:290200
		C2H2 Zn finger	1070..1090	CDD:275368
YPR015C	NP_015340.1	COG5048	<17..247	CDD:227381	65/266 (24%)
		C2H2 Zn finger	187..207	CDD:275370	8/19 (42%)
		C2H2 Zn finger	215..237	CDD:275370	6/21 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23233
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100