DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ab and CG6765

DIOPT Version :9

Sequence 1:	NP_476562.1	Gene:	ab / 34560	FlyBaseID:	FBgn0264442	Length:	904	Species:	Drosophila melanogaster
Sequence 2:	NP_001261582.1	Gene:	CG6765 / 38971	FlyBaseID:	FBgn0035903	Length:	681	Species:	Drosophila melanogaster

Alignment Length:	738	Identity:	151/738 - (20%)
Similarity:	240/738 - (32%)	Gaps:	185/738 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    76 QHYALKWNDFQSSILSSFRHLRDEEDFVDVTLACDERS-----------FTAHKVVLSACSPYFR 129
            ::|.|||:...:.:.||...|...|.|.||.|.....|           .:|||.:|||.|.:|.
  Fly     4 ENYHLKWDSHLTYLNSSIATLYKNEKFADVVLYSSYNSSGIPSDIPTVGISAHKFILSASSQFFA 68

  Fly   130 RLLKANPCEHP-----IVILRDVRCDDVENLLSFMYNGEVNVSHEQLPDFLKTAHLLQIRGL--- 186
            .:.:..|..:|     :|:..|:....::.|:.:||:||..||::.|.:.|:...:|:||||
  Fly    69 TMFETAPITNPNGVLYVVLPPDLSHRAIQILVQYMYSGEATVSNDILNEVLRGGEILKIRGLCRT 133

  Fly   187 ADVNGGYPYSKALSAALSHNSSNNNNNNSSSNNSLSNNNNNNNNNAESSNHNKISSYLSPN---- 247
            :..|||...|...:....|:.:.:.:...:|...:||..............:.:|:.|..:
  Fly   134 SSSNGGGSGSVVTTTHHPHSLAGHLHPREASTMYMSNGTRTALPPPPPPPQSTMSAQLQGDLYAS 198

  Fly   248 ----QTSAACNNSSNSNSNNHSSSHNN----------------------------------SSSN 274
                .|..|.::...|:.::|.:.||.                                  :||:
  Fly   199 KPGGSTRFALDHHHLSSHHSHLNHHNPQQQFRGLGASVMPKDSPVIIKSPKLAAHTGLLTVASSS 263

  Fly   275 NISGSLNSSL------NSPFSAP-QI------PPPVTASSAAAAAAAAASLTAAVAAAAAATAAS 326
            .:..|:|..:      ...|:|| |:      |||.|.::.......:...:.|..:...:....
  Fly   264 KLGISVNKEVAIDPEDKCCFAAPGQLESQSHPPPPTTTTTTVGGGGGSVGGSGAPPSQPISICTE 328

  Fly   327 AGSSS---SAASGQTSGTPAIQELKASSAASPVRNP---------NPNPSKASSSNHWDMGEMEG 379
            .|.||   :|..|.......::..:....|...||.         ....:...|.::::....|.
  Fly   329 VGCSSCPLTAGPGADQAETTLRRTEYEEQALRERNEVGLVFERRLRRESACERSRDYYEAPHFEH 393

  Fly   380 SRKSHLT----PPPQKRIKSADLFRAQHGISPERLLLDREFPVAGQHPLT-RNRSGRDTSKDRER 439
            ...|.|.    ||||:...|          .|..|.....|....|.|.. .|.....:|.....
  Fly   394 VVSSRLAATPPPPPQQAPPS----------HPPTLRHPHNFLTIKQEPTDWSNNPPNASSASNNN 448

  Fly   440 NLE----------LRESLLGQALENSNGQQANPKHELGQSAGEDSNS--------------SDTE 480
            |||          |...:....|| .|..:..|..|..:....|.|:              .||:
  Fly   449 NLEELPLASPKQPLDFKMSAVKLE-VNRDRGTPSEESEEHTLRDYNNFKQLLVCEICQKSFEDTK 512

  Fly   481 PSDRGDGQHDGTLDGIDNQRSHSFPNAFLGLQGIPGLLPGPSGINSDFVSRRSLEMR-VRATDPR 544
            ...|..|.|.|...| ..:|:               |||. |...|...:..:|.:| |:...|
  Fly   513 MLVRHLGTHAGDPTG-GTERN---------------LLPS-SASGSTTSASSNLALRSVKTYVP- 559

  Fly   545 PCPKCGKIYRSAHTLRTHLEDKHTVCPGYRCVLCGTVAKSRNSLHSHMSRQHRGISTKDLPVLPM 609
                  |..|.......:::..|..   ..|.||.|...:......||:.||..|
  Fly   560 ------KKRRRVSQQENNMDHDHVT---LLCDLCSTSFDTPAEWVRHMNSQHTEI---------- 605

  Fly   610 PSAFDPELASRLLAKAGVKISPAELRARASPTGGSGSSGGGGGGGSSQAKLDLSNASGG------ 668
                  |||.....|.|      |.:.:..|...:.||.........|.|...|.|:..
  Fly   606 ------ELAMFNSKKDG------EQKGQQPPPPPATSSSSTVSNSQMQPKYPSSTATRSTHSLML 658

  Fly   669 ---PMDDAEDSDDDPEDLTTGNG 688
               ...||..:...|...|:.||
  Fly   659 HKMSNSDAVATTTSPGASTSPNG 681

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ab	NP_476562.1	BTB	93..189	CDD:279045	33/114 (29%)
		BTB	104..189	CDD:197585	30/103 (29%)
		zf-Di19	545..597	CDD:283297	10/51 (20%)
		C2H2 Zn finger	546..567	CDD:275371	2/20 (10%)
		C2H2 Zn finger	575..596	CDD:275371	6/20 (30%)
CG6765	NP_001261582.1	BTB	24..132	CDD:279045	33/107 (31%)
CG6765	NP_001261582.1	BTB	53..130	CDD:197585	24/76 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451897
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000141
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23110
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.940