DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ab and CG15812

DIOPT Version :9

Sequence 1:	NP_476562.1	Gene:	ab / 34560	FlyBaseID:	FBgn0264442	Length:	904	Species:	Drosophila melanogaster
Sequence 2:	NP_523897.2	Gene:	CG15812 / 38379	FlyBaseID:	FBgn0035405	Length:	518	Species:	Drosophila melanogaster

Alignment Length:	545	Identity:	114/545 - (20%)
Similarity:	189/545 - (34%)	Gaps:	145/545 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    80 LKWNDFQSSILSSFRHLRDEEDFVDVTLAC-DERSFTAHKVVLSACSPYFRRLLKANP-CEHPIV 142
            |||....|:|:...|.||::....:|.||. |.....||..|||.||...|.||...| .:...:
  Fly     4 LKWMGHSSTIMDIQRSLRNDNQHCEVVLASRDGVRVRAHLFVLSTCSELMRNLLVDVPRGQEATI 68

  Fly   143 ILRDVRCDDVENLLSFMYNGEVNVSHEQLPDFLKTAHLLQIRGLADVNGGYPYSKALSAALSH-- 205
            :|.|:|.|.:|.:|||:|.||.::....||:||:..:||.|:                :|:|.
  Fly    69 MLPDIRGDLLECMLSFIYMGETSLPSASLPEFLEAINLLGIK----------------SAISFEC 117

  Fly   206 NSSNNNNNNSSSNNSLSNNNNNNNNNAESSNHNKISSYLSPN-QTSAACNNSSNSNSNNHSSSHN 269
            |.|.:..:....|:||:..:..:....:.:....:.....|: ..|......:.|   .|..||:
  Fly   118 NPSASPPSVDVENHSLAVESAKSITGLQIAEAELLDDEEEPHPMVSVPATTLAGS---QHQPSHS 179

  Fly   270 NSSSNNISGSLNSSLNSPFSAPQIPPPVTASSAAAAAAAAASLTAAVAAAAAATAASAGSSSSAA 334
            :.|...|.             ...||.:|.|......:::.:...........|...:.||.|..
  Fly   180 SRSLEYID-------------VYEPPKITYSIEHMDGSSSGNQFILTENTGTFTITQSASSLSKI 231

  Fly   335 SGQTSGTPAIQELKASSAASPVRNPNPNPSKASSSNHWDMGEMEGSRKSHLTPPPQKRIKSADLF 399
            ....:||                          |....|:|:.:               ..|||
  Fly   232 EADETGT--------------------------SGAEVDLGDDD---------------VDADL- 254

  Fly   400 RAQHGISPERLLLDREFPVAGQHPLTRNRSGRDTSKDRERNLELRESLLGQALENSNGQQANPKH 464
             |:.....|..::|.||  |...||....:|.:...|.    ::.:.|:.:.:::...:....|.
  Fly   255 -AEDSEEHESQMIDEEF--AQADPLMELEAGTEMDDDD----DVHDQLVDEEIDDKPRKLGGGKT 312

  Fly   465 ELGQ--SAGEDSNSSDTEPSDRGDGQHDGTLDGIDNQRSHSFP----------NAFLGLQG---- 513
            .:.:  ||......||.:|:                 |...|.          |..|.|..
  Fly   313 RIRRPISAKAVKRLSDCKPT-----------------RIQQFAALKREVKDDINDALDLAADAVI 360

  Fly   514 IPGLLPGPSGINSDFVSRRSLEMRVRATDP------RPCPKCGKIY---RSAHTLRTHLEDKHTV 569
            |.||....:....| :|:..|..||| |:|      |..|...:.|   ::.|:|::
  Fly   361 IEGLSLQKAADRFD-ISKTVLWRRVR-TNPAYMRNNRERPSLQEAYERLKNGHSLKS-------- 415

  Fly   570 CPGYRCVLCGTVAKSRNSLHSHMSR 594
                   :...:....::||.|..|
  Fly   416 -------ISSELQIPMSTLHRHKVR 433

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ab	NP_476562.1	BTB	93..189	CDD:279045	36/97 (37%)
		BTB	104..189	CDD:197585	33/86 (38%)
		zf-Di19	545..597	CDD:283297	8/53 (15%)
		C2H2 Zn finger	546..567	CDD:275371	4/23 (17%)
		C2H2 Zn finger	575..596	CDD:275371	4/20 (20%)
CG15812	NP_523897.2	BTB	20..113	CDD:279045	35/108 (32%)
		BTB	35..118	CDD:197585	32/98 (33%)
		HTH_psq	348..392	CDD:283007	14/45 (31%)
		HTH_psq	458..501	CDD:283007
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1229475at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23110
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	3.020