DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ab and CG8924

DIOPT Version :9

Sequence 1:	NP_476562.1	Gene:	ab / 34560	FlyBaseID:	FBgn0264442	Length:	904	Species:	Drosophila melanogaster
Sequence 2:	NP_573091.1	Gene:	CG8924 / 32557	FlyBaseID:	FBgn0030710	Length:	514	Species:	Drosophila melanogaster

Alignment Length:	416	Identity:	97/416 - (23%)
Similarity:	161/416 - (38%)	Gaps:	101/416 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    76 QHYALKWNDFQSSILSSFRHLRDEEDFVDVTLACDERSFTAHKVVLSACSPYFRRLLKANPCEHP 140
            |.:.::||....||.::|..|...:.||||||||:.:....|::||:|||.||..:|..:||:||
  Fly     6 QEFCVRWNSHLGSIGAAFPQLLAGQRFVDVTLACEGQQVHCHRLVLAACSTYFEAILAEHPCKHP 70

  Fly   141 IVIL-RDVRCDDVENLLSFMYNGEVNVSHEQLPDFLKTAHLLQIRGLADVNGGYPYSKALSAAL- 203
            ::|| |:::..:::.|:.|||.|||||:...|...|:.|..||||||........|.|...|:|
  Fly    71 VIILPREIKLWEIQALVDFMYKGEVNVTQAGLGQLLRCAEQLQIRGLYGSEAPINYKKLQQASLE 135

  Fly   204 ------------------------SHNSSNNNNNNSSSNNSLSNNN------NNNNNNAESSNHN 238
                                    :.||:.:....:||...|..|:      ...|.:|......
  Fly   136 AAKDPAATTARSFKHVDSAETDDAATNSTTSTTMTTSSAPPLPVNHQQPTVLKRQNPDARQQQQQ 200

  Fly   239 KISSYLS--PNQTSAACNNSSNSNSNNHSSSHNNSSSNNISG----------------------S 279
            :....:.  |....:.....|.:.|.|...||:|:.:.:.||                      :
  Fly   201 QQQQQVQQRPQINGSNAQQPSKATSTNVLGSHSNAPTEDDSGDEVPNNWNAYGEQFDDCNISAQA 265

  Fly   280 LNSSLNSPFSAPQIPPPV-------------------------TASSAAAAAAAAASLTAAVAAA 319
            :::.:|...|..|....:                         ..||.|......:.|:.::...
  Fly   266 VDNKMNVHLSLQQARMQMQLQQQQYLDSNVEDDHNYVAAHDENNDSSFATGVPCGSGLSLSLDTD 330

  Fly   320 AAATA-ASAGSSSSAASGQTSGTPAIQELKASSAASPVRNPNPNPSKASSSNHWDMGEMEGSRKS 383
            ...:| .|.|.|.|:..|.||    .:.::.|.|           |.|.::.....||...:..:
  Fly   331 LDTSANTSGGLSHSSIDGYTS----YKRVRRSEA-----------SLAQAAKCVSKGETFQTVSN 380

  Fly   384 HLTPPPQKRIKSADLFRAQHGISPER 409
            ....|    :.:...:.|:.||.|:|
  Fly   381 MFNIP----VSTIRFYMARKGILPKR 402

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ab	NP_476562.1	BTB	93..189	CDD:279045	44/96 (46%)
		BTB	104..189	CDD:197585	40/85 (47%)
		zf-Di19	545..597	CDD:283297
		C2H2 Zn finger	546..567	CDD:275371
		C2H2 Zn finger	575..596	CDD:275371
CG8924	NP_573091.1	BTB	25..117	CDD:279045	41/91 (45%)
		BTB	34..117	CDD:197585	38/82 (46%)
		MerR	378..407	CDD:278788	6/29 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451898
Domainoid	1	1.000	59	1.000	Domainoid score	I10615
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1229475at2759
OrthoFinder	1	1.000	-	-		FOG0000141
OrthoInspector	1	1.000	-	-		otm40394
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR23110
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.950