Protein Alignment ab and Zbtb37

DIOPT Version :10

• Sequence 1: NP_476562.1
• Gene: ab / 34560
• FlyBaseID: FBgn0264442
• Length: 904
• Species: Drosophila melanogaster
• Sequence 2: NP_775600.1
• Gene: Zbtb37 / 240869
• MGIID: 2444467
• Length: 504
• Species: Mus musculus
• Alignment Length: 608
• Identity: 134/608 - (22%)
• Similarity: 209/608 - (34%)
• Gaps: 162/608 - (26%)

  Fly    84 DFQSSILSSFRHLRDEEDFVDVTLACDERSFTAHKVVLSACSPYFRRLLKANPCEHPIVILRDVR 148
            ||.:|:||....||.:....|:.:....::|.||||||:|.|||||..:..|  |...|.:..::
Mouse    15 DFSNSVLSHLNQLRMQGRLCDIVVNVQGQAFRAHKVVLAASSPYFRDHMSLN--EMSTVSISVIK 77

  Fly   149 CDDV-ENLLSFMYNGEVNVSHEQLPDFLKTAHLLQIRGLAD----VNGGYPYS---KALSAALSH 205
            ...| |.||||.|.|.:.:....:..:|..|..||::.:.|    :..|..:.   ..:.|.||.
Mouse    78 NPTVFEQLLSFCYTGRICLQLADIISYLTAASFLQMQHIIDKCTQILEGIHFKINVAEVEAELSQ 142

  Fly   206 NSSNNNNNNSSSNNSLSNNNNNNNNNAESSNHNKISSYLSPNQTSAACNNSSNSNSNNHSSSHNN 270
            ..:.:......|:.:..|.|.:                |||                     .:|
Mouse   143 TRTKHQERPPESHRATPNLNRS----------------LSP---------------------RHN 170

  Fly   271 SSSNNISGSLNSSLN----SPFSAPQIPPPVTASSAAAAAAAAASLTAA----VAAAAAATAASA 327
            :|..|..|.:::.|:    ||...|..|..:..||.|........:..|    |....|...|.:
Mouse   171 ASKGNWRGQVSAVLDIRELSPPEEPTSPQIIEQSSDAEGREPILRINRAGQWYVETGLADQGARS 235

  Fly   328 GSSSSAASGQTSGTPAIQELKASSAASPVRNPNPNPSKASSSNHWDMGEMEGSRKSHLTPPPQKR 392
            |............|..::|.         ..|...||          || :||....:|
Mouse   236 GDEVRVLGAVHIKTENLEEW---------LGPENQPS----------GE-DGSSAEEVT------ 274

  Fly   393 IKSADLFRAQHGISPERLLLDREFPVAGQHPLTRNRSG----RDTSKDRER--------NLELRE 445
              :..:....||             ..||...|...||    |.||.:.:|        ::..|.
Mouse   275 --AMVIDTTGHG-------------SIGQESYTLGSSGAKVARPTSSEVDRFSPSGSVVSMTERH 324

  Fly   446 SLLGQALENSNGQQANPKHELGQSAGEDSNSS---------DTEPSDRGDGQHDGTLDGIDNQRS 501
                :|...|.|:...|| :|.....|.:...         :.|.|:|. .:::..|..|...:|
Mouse   325 ----RARSESPGRMDEPK-QLSSQVEESAMMGVSAYVEYLREQEVSERW-FRYNPRLTCIYCAKS 383

  Fly   502 HSFPNAFLGLQGIPGLLPGPSGINSDFVSRRSLEMRVR---ATDPRPCPKCGKIYRSAHTLRTHL 563
                                      |..:.||:..:|   ...|..|..|||.|.....|..|:
Mouse   384 --------------------------FNQKGSLDRHMRLHMGITPFVCRMCGKKYTRKDQLEYHI 422

  Fly   564 EDKHTVCPGYRCVLCGTVAKSRNSLHSHMSRQHRGISTKDLPVLPMPSAFDPELASRLLAKAGVK 628
            . |||....:.|.:||.....:..|:.|..:.|.|.    :| |..|.:..||  :.:.::...:
Mouse   423 R-KHTGNKPFHCHVCGKSFPFQAILNQHFRKNHPGC----IP-LEGPHSISPE--TTVTSRQAEE 479

  Fly   629 ISPA--ELRARASPTGGSGSSGG 649
            .||:  |:.|......||.|:.|
Mouse   480 GSPSHEEIVAPGESAQGSVSTTG 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ab	NP_476562.1	BTB_POZ_BAB-like	102..185	CDD:349624	29/83 (35%)
		zf-Di19	545..597	CDD:428539	15/51 (29%)
		C2H2 Zn finger	546..567	CDD:275371	7/20 (35%)
		C2H2 Zn finger	575..596	CDD:275371	5/20 (25%)
Zbtb37	NP_775600.1	BTB_POZ_ZBTB37	9..131	CDD:349531	38/117 (32%)
		C2H2 Zn finger	377..397	CDD:275368	6/45 (13%)
		zf-H2C2_2	389..414	CDD:463886	9/24 (38%)
		zf-C2H2	403..425	CDD:395048	7/22 (32%)
		C2H2 Zn finger	405..425	CDD:275368	7/20 (35%)
		zf-H2C2_2	418..440	CDD:463886	8/22 (36%)
		C2H2 Zn finger	433..451	CDD:275368	5/17 (29%)