DRSC/TRiP Functional Genomics Resources

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Protein Alignment ab and Zbtb45

DIOPT Version :9

Sequence 1:NP_476562.1 Gene:ab / 34560 FlyBaseID:FBgn0264442 Length:904 Species:Drosophila melanogaster
Sequence 2:NP_001019870.1 Gene:Zbtb45 / 232879 MGIID:2685003 Length:520 Species:Mus musculus


Alignment Length:590 Identity:119/590 - (20%)
Similarity:185/590 - (31%) Gaps:172/590 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly    74 HQQHYALKWNDFQSSILSSFRHLRDEEDFVDVTLACDERSFTAHKVVLSACSPYFRRLLKANPCE 138
            |..|.    .:|..|:|.:....|....|.|||:...|.|..||:.||:|.||:|:..|.....|
Mouse     8 HHIHL----QNFSRSLLETLNGQRLGGHFCDVTVRIREASLRAHRCVLAAGSPFFQDKLLLGHSE 68

  Fly   139 ---HPIVILRDVRCDDVENLLSFMYNGEVNVSHEQLPDFLKTAHLLQIRGLADVNGGYPYSKALS 200
               .|:|..:.||     .|:.|:|:|.:.|:..:....|..|.:|:|:.:.|     ..::.::
Mouse    69 IRVPPVVPAQTVR-----QLVEFLYSGSLVVAQGEALQVLTAASVLRIQTVID-----ECTQIIA 123

  Fly   201 AALSHNSSNNNNNNSSSNNSLSNNNNNNNNNAESSNHNKISSYLSPNQTSAACNNSSNSNSNNHS 265
            .|...|:.                       |.:.....:...|:|.|......:...:....|.
Mouse   124 RARVPNTP-----------------------APAPLPPPVPPPLAPAQLRHRLRHLLAARPPGHP 165

  Fly   266 SSHNNSSSNNISGSLNSSLNSPFSAPQIPPPVTASSAAAAAAAAASLTAAV---------AAAAA 321
                     |.:.|......:....|..|.|:.|....|..|    ||||.         .....
Mouse   166 ---------NAAHSRKQRQPARLQLPAPPAPIKAEGPDAEPA----LTAAPEDRGEEDDDEETDE 217

  Fly   322 ATAASAGSSSSAASGQTSGTPAIQELKA---SSAASPVRNPNPNPSKASSSNHWDMGEMEGSRKS 383
            .|.|..|.......|:....||..:...   ::||...|...|     :|:...|.|   |:.:.
Mouse   218 ETDAEEGEGGGGGPGEGQAPPAFPDCAGGFLTTAADSAREDPP-----ASTGITDYG---GAGRD 274

  Fly   384 HLTPPPQKRIKSADLF-----RAQHGIS---PERLLLDREFP----VAGQHPLTRNRSGRDTSKD 436
            .|    :....:.|:|     .|.|..|   ||...::...|    :||..|......|...:  
Mouse   275 FL----RGTGVTEDVFPDSYVSAWHEESSGGPESCPVETSAPPDCALAGPRPTGVKTPGPPVA-- 333

  Fly   437 RERNLELRESLLGQALENSNGQQANPKHELGQSAGEDSNSSDTEPSDRGDG-----------QHD 490
                                   ..|.|     .|.....:.|.|:..|..           |.|
Mouse   334 -----------------------LFPFH-----LGAPGPPAPTPPTPSGPAPAPPPTFYPTLQPD 370

  Fly   491 GTLDGIDNQRSHSFPNAFLG---------------LQGIPGLLPGPSG----------INSDFVS 530
            ..            |:|.||               :.|.|...||..|          ....|.|
Mouse   371 AA------------PSAQLGETQAVPAAPAAQATAISGTPVRAPGGQGAEQPAYECSHCRKTFSS 423

  Fly   531 RRSL--EMRVRATD-PRPCPKCGKIYRSAHTLRTHLEDKHTVCPGYRCVLCGTVAKSRNSLHSHM 592
            |::.  .|.:.:.: |..|..|.:.:.....|..|:. .||....::|.:|......::||:.||
Mouse   424 RKNYTKHMFIHSGEKPHQCAVCWRSFSLRDYLLKHMV-THTGVRAFQCAVCAKRFTQKSSLNVHM 487

  Fly   593 SRQHR 597
             |.||
Mouse   488 -RTHR 491

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
abNP_476562.1 BTB 93..189 CDD:279045 30/98 (31%)
BTB 104..189 CDD:197585 28/87 (32%)
zf-Di19 545..597 CDD:283297 13/51 (25%)
C2H2 Zn finger 546..567 CDD:275371 4/20 (20%)
C2H2 Zn finger 575..596 CDD:275371 7/20 (35%)
Zbtb45NP_001019870.1 BTB_POZ_ZBTB45 15..126 CDD:349538 34/120 (28%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 182..272 24/101 (24%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 337..372 7/39 (18%)
zf-C2H2 412..434 CDD:333835 4/21 (19%)
C2H2 Zn finger 414..434 CDD:275368 4/19 (21%)
C2H2 Zn finger 442..462 CDD:275368 4/20 (20%)
zf-H2C2_2 454..479 CDD:372612 6/25 (24%)
zf-C2H2 468..490 CDD:333835 7/22 (32%)
C2H2 Zn finger 470..490 CDD:275368 7/20 (35%)
C2H2 Zn finger 497..517 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

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