Protein Alignment Ca-beta and cacnb3a

DIOPT Version :9

• Sequence 1: NP_001260375.1
• Gene: Ca-beta / 34557
• FlyBaseID: FBgn0259822
• Length: 844
• Species: Drosophila melanogaster
• Sequence 2: XP_005162051.1
• Gene: cacnb3a / 565158
• ZFINID: ZDB-GENE-060221-2
• Length: 555
• Species: Danio rerio
• Alignment Length: 586
• Identity: 293/586 - (50%)
• Similarity: 364/586 - (62%)
• Gaps: 93/586 - (15%)

  Fly     1 MVQ-RASSSDAPSVQGGQ---------------HRESRFGLGYPSYQSGYNKLF--TQGSADSNY 47
            ||| :.|.|.|..:.|.:               .|:.||.....|..|.....|  .||||||..
Zfish     1 MVQVKMSKSSADPLSGVESASQSHYFQLPRKLPKRKGRFKRSDGSTSSDTTSSFIKRQGSADSYT 65

  Fly    48 SQPS-SDLSLDEEKESLRREKERQALSQLDKARSKPVAFAVRTNVAYDGAIDDDSPVQGGAVSFE 111
            |:|| ||||.:|::|:.|||.||||..||::|:||||||||:|||.|.||:|::.||||.|::||
Zfish    66 SRPSDSDLSAEEDREAYRREAERQAQLQLERAKSKPVAFAVKTNVNYCGALDEECPVQGAAINFE 130

  Fly   112 IREFLHIKEKYDNNWWIGRLVKEGCDVGFIPSPAKLDNIRMQNQTRPSRLYGTKGSSSGNLGAGG 176
            .::||||||||:|:||||||||||.|:.|||||.:|:.:|::.:.:..|..|...||.|::.:||
Zfish   131 AKDFLHIKEKYNNDWWIGRLVKEGADISFIPSPLRLEAMRIKQEQKQQRKSGNSSSSLGDMVSGG 195

  Fly   177 QAGAEPSRGSTPPTPGDESDSMGPGRHGKTPAAAANKEKRKPFFKKQETASPYDVVPSMRPVVLV 241
            ..       ||||:.|:                  .|:|    .|:.|...||||||||||||||
Zfish   196 WR-------STPPSAGE------------------TKQK----LKQTEHIPPYDVVPSMRPVVLV 231

  Fly   242 GPSLKGYEVTDMMQKALFDFLKHRFEGRIIITRVMADISLAKRSIMNNPSKRAIMERSSSRSDCL 306
            |||||||||||||||||||||||||:|||.||||.||:||||||::|   ||.|||||::|:. |
Zfish   232 GPSLKGYEVTDMMQKALFDFLKHRFDGRISITRVTADLSLAKRSVLN---KRPIMERSNTRTS-L 292

  Fly   307 GKVQEEIERIFELARSLQLVVLDCDTINHPSQLAKTSLAPTIVYLKISSSKVLQRLIKSRGKSQA 371
            .:||.|||||||||::||||:||.||||||:|||||||||.|||:|::|.||||||||||||||:
Zfish   293 AEVQSEIERIFELAKTLQLVILDADTINHPAQLAKTSLAPIIVYVKVTSPKVLQRLIKSRGKSQS 357

  Fly   372 KNLSVQMVAAEKLAQCPPDMFDVILDENQLEDACEHIAEYLETYWKATH-PDIRAVPPIARP--- 432
            |:|:|||:||:||.||||:|||||||||||||||||:|||||.||:||| |....:.|:...
Zfish   358 KHLNVQMMAADKLTQCPPEMFDVILDENQLEDACEHLAEYLEVYWRATHLPGTTPLNPLLEQNLM 422

  Fly   433 LPQEASPSADPARLGPTPPVDG--EEFVDEQDPRMGMSGGD------REGSRERDRDSRERERER 489
            .|..|..|....:|.|.....|  ||...|||..|......      |.||........|.|.|.
Zfish   423 TPPSAISSLQNQQLSPAGGGVGVEEEEQGEQDSLMPSDEASDSRSLHRGGSSSLHPPEDEEEEEE 487

  Fly   490 ERERDYWDREF----------NRD----------RSSKDR---ERDLE------WERERAREWER 525
            |.:.||.....          ||:          ..|:||   :||.:      ..|:|:|.|.|
Zfish   488 EEDDDYQPHRHSNPYRDVYPPNRNHPGGIHSANGHESQDRLLQQRDSQDGHNQRNNRQRSRAWPR 552

  Fly   526 E 526
            :
Zfish   553 D 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ca-beta	NP_001260375.1	VGCC_beta4Aa_N	41..81	CDD:288872	24/40 (60%)
		SH3_CACNB	85..146	CDD:212797	42/60 (70%)
		Guanylate_kin	234..415	CDD:279019	144/180 (80%)
		NK	244..416	CDD:302627	134/171 (78%)
cacnb3a	XP_005162051.1	VGCC_beta4Aa_N	59..100	CDD:288872	24/40 (60%)
		SH3	100..167	CDD:302595	46/66 (70%)
		Guanylate_kin	224..401	CDD:279019	144/180 (80%)
		NK	234..402	CDD:302627	134/171 (78%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	298	1.000	Domainoid score	I1418
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000994
OrthoInspector	1	1.000	-	-		otm24806
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11824
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	6.010