Protein Alignment Ca-beta and ccb-1

DIOPT Version :10

• Sequence 1: NP_001260375.1
• Gene: Ca-beta / 34557
• FlyBaseID: FBgn0287724
• Length: 844
• Species: Drosophila melanogaster
• Sequence 2: NP_491193.2
• Gene: ccb-1 / 171933
• WormBaseID: WBGene00000368
• Length: 526
• Species: Caenorhabditis elegans
• Alignment Length: 427
• Identity: 270/427 - (63%)
• Similarity: 328/427 - (76%)
• Gaps: 21/427 - (4%)

  Fly    40 QGSADSNYSQPSSDLSLDE-EKESLRREKERQALSQLDKARSKPVAFAVRTNVAYDGAIDDDSPV 103
            :||.|||:|. ..:|.|:. .:|:|||:.||||..||::|:.|||||||.|||.|||::||||||
 Worm     6 RGSGDSNFSH-HDELELEAGNRETLRRDAERQAALQLERAKYKPVAFAVCTNVEYDGSVDDDSPV 69

  Fly   104 QGGAVSFEIREFLHIKEKYDNNWWIGRLVKEGCDVGFIPSPAKLDNIRMQNQTRPSRLYGTKGSS 168
            .|.||||::::||||||||:|:||||||||||.|:||||||.||:::|  .||..|..: .:.:|
 Worm    70 HGCAVSFKVKDFLHIKEKYNNDWWIGRLVKEGHDLGFIPSPVKLESLR--QQTAKSGKF-KQSTS 131

  Fly   169 SGNLGA-GGQAGAEPSRGSTPPTPGDESDSMGPGRHGKTPAAAANKEKRKPFFKK--QETASPYD 230
            :.|||| ........|||||||||.|  |.....:..........|||:|..|||  ||...|||
 Worm   132 ATNLGALDNMMPRSGSRGSTPPTPDD--DEYNAKKMTNIVTTPPTKEKKKLIFKKVQQENVPPYD 194

  Fly   231 VVPSMRPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGRIIITRVMADISLAKRSIMNNPSKRAI 295
            |||||||||||||||||||||||||||:||:||||||||||||||.|||||||||::|||:|||:
 Worm   195 VVPSMRPVVLVGPSLKGYEVTDMMQKAVFDYLKHRFEGRIIITRVTADISLAKRSLLNNPNKRAM 259

  Fly   296 MERSSSR-SDCLGKVQEEIERIFELARSLQLVVLDCDTINHPSQLAKTSLAPTIVYLKISSSKVL 359
            |||::|| |:.|.::|.|||||||||||:|||||||||||||||||||||||..||:||||.|||
 Worm   260 MERANSRTSNSLAEIQTEIERIFELARSMQLVVLDCDTINHPSQLAKTSLAPIHVYIKISSPKVL 324

  Fly   360 QRLIKSRGKSQAKNLSVQMVAAEKLAQCPPDMFDVILDENQLEDACEHIAEYLETYWKATHPDIR 424
            |||||||||||::|::||||||||||||..::|||:||||||||||||:|:::|.||:||||.:|
 Worm   325 QRLIKSRGKSQSRNMNVQMVAAEKLAQCQAELFDVLLDENQLEDACEHLADFMEAYWRATHPPVR 389

  Fly   425 AVPPIARPLPQEASPSA--DPARL--------GPTPP 451
            :.|.|.|...:...||.  .||::        |..||
 Worm   390 SPPRIKRNPMENRGPSTLFTPAQMMQGFQGNAGQLPP 426

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ca-beta	NP_001260375.1	VGCC_beta4Aa_N	41..81	CDD:463445	19/40 (48%)
		SH3_CACNB	85..146	CDD:212797	46/60 (77%)
		Guanylate_kin	234..415	CDD:395500	147/181 (81%)
ccb-1	NP_491193.2	VGCC_beta4Aa_N	7..47	CDD:463445	19/40 (48%)
		SH3_CACNB	51..112	CDD:212797	46/60 (77%)
		Guanylate_kin	198..380	CDD:395500	147/181 (81%)