Protein Alignment Ca-beta and cacnb2

DIOPT Version :9

• Sequence 1: NP_001260375.1
• Gene: Ca-beta / 34557
• FlyBaseID: FBgn0259822
• Length: 844
• Species: Drosophila melanogaster
• Sequence 2: XP_031759789.1
• Gene: cacnb2 / 100495884
• XenbaseID: XB-GENE-962360
• Length: 647
• Species: Xenopus tropicalis
• Alignment Length: 638
• Identity: 327/638 - (51%)
• Similarity: 399/638 - (62%)
• Gaps: 126/638 - (19%)

  Fly     7 SSDAPSVQ---GGQHRESRF--GLGYPSYQSGYNKLFTQGSADSNYSQPS-SDLSLDEEKESLRR 65
            |.:.|:||   .|..|:.||  ..|..|..:..|....||||||..|:|| ||:||:|::|::||
 Frog    21 SLENPAVQTYGKGARRKHRFKGSDGSTSSDTTSNSFVRQGSADSYTSRPSDSDVSLEEDREAVRR 85

  Fly    66 EKERQALSQLDKARSKPVAFAVRTNVAYDGAIDDDSPVQGGAVSFEIREFLHIKEKYDNNWWIGR 130
            |.||||.:||:||::|||||||||||.|..|.||:.||.|.|:|||.::|||:|||::|:|||||
 Frog    86 EAERQAQAQLEKAKTKPVAFAVRTNVGYSAAHDDEVPVPGMAISFEAKDFLHVKEKFNNDWWIGR 150

  Fly   131 LVKEGCDVGFIPSPAKLDNIRMQNQ--TRPSRLYGTK--GSSSGNLGAGGQAGAEP-SRGSTPPT 190
            ||||||::||||||.||:|:|:|::  |:..:.|.:|  |:||.:||     ...| ||.||||:
 Frog   151 LVKEGCEIGFIPSPVKLENMRIQHEQKTKQGKFYTSKSGGNSSSSLG-----DVVPSSRRSTPPS 210

  Fly   191 PGDESDSMG---------PGRHGKTPAAAAN-------KEKRKPFFKKQETASPYDVVPSMRPVV 239
            ...:.|:.|         |..| ::|..:||       ||||.|||||.|...||||||||||||
 Frog   211 SAIDLDATGLEAEELDIPPANH-RSPKPSANSLTSPHSKEKRMPFFKKTEHIPPYDVVPSMRPVV 274

  Fly   240 LVGPSLKGYEVTDMMQKALFDFLKHRFEGRIIITRVMADISLAKRSIMNNPSKRAIMERSSSRSD 304
            |||||||||||||||||||||||||||||||.||||.|||||||||::|||||.||:|||::||.
 Frog   275 LVGPSLKGYEVTDMMQKALFDFLKHRFEGRISITRVTADISLAKRSVLNNPSKHAIIERSNTRSS 339

  Fly   305 CLGKVQEEIERIFELARSLQLVVLDCDTINHPSQLAKTSLAPTIVYLKISSSKVLQRLIKSRGKS 369
             |.:||.||||||||||:|||||||.||||||:||.||||||.|||:||||.|||||||||||||
 Frog   340 -LAEVQSEIERIFELARTLQLVVLDADTINHPTQLGKTSLAPIIVYVKISSPKVLQRLIKSRGKS 403

  Fly   370 QAKNLSVQMVAAEKLAQCPPDMFDVILDENQLEDACEHIAEYLETYWKATHPD---------IRA 425
            |||:|:||||||:|||||||:|||||||||||||||||:|:|||.|||||||.         .|.
 Frog   404 QAKHLNVQMVAADKLAQCPPEMFDVILDENQLEDACEHLADYLEAYWKATHPPSSNPTNVLLSRT 468

  Fly   426 VPPIARPL-PQEASPS------------ADPARLGPTPPVDGEEFVDEQDPRMG--------MSG 469
            :.....|: |..||.:            :.|.|.|........|...:...|..        .||
 Frog   469 LTTATLPITPTSASNTQQSSQGDHQNQHSAPERTGSVEEDTSAEATKKSHHRSSSSAQHHNHRSG 533

  Fly   470 GDREGSRE------------------------------------------------RDRDSRERE 486
            |.|..||:                                                |.::||.|.
 Frog   534 GSRGLSRQDTFDNETQANRDSVYLDPKEDFSSEHGAPPDSHREHNHRDETHAVSEHRHKESRHRS 598

  Fly   487 RERERERDYWDREFNRDRS---SKDR--ERDLEWERERAREWERERERDWDRE 534
            .|.:||.|:  .|.|:.||   |:||  |:|.|..|:|       .|.||:|:
 Frog   599 NEPDREHDH--NECNKPRSRHKSRDRHCEKDGEVPRKR-------NEADWNRD 642

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ca-beta	NP_001260375.1	VGCC_beta4Aa_N	41..81	CDD:288872	25/40 (63%)
		SH3_CACNB	85..146	CDD:212797	42/60 (70%)
		Guanylate_kin	234..415	CDD:279019	154/180 (86%)
		NK	244..416	CDD:302627	144/171 (84%)
cacnb2	XP_031759789.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	300	1.000	Domainoid score	I1406
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	535	1.000	Inparanoid score	I1175
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000994
OrthoInspector	1	1.000	-	-		otm47649
Panther	1	1.100	-	-	LDO	PTHR11824
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1029
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	9.060