Protein Alignment CG6287 and Phgdh

DIOPT Version :10

• Sequence 1: NP_609496.1
• Gene: CG6287 / 34554
• FlyBaseID: FBgn0032350
• Length: 332
• Species: Drosophila melanogaster
• Sequence 2: NP_113808.1
• Gene: Phgdh / 58835
• RGDID: 61987
• Length: 533
• Species: Rattus norvegicus
• Alignment Length: 325
• Identity: 172/325 - (52%)
• Similarity: 236/325 - (72%)
• Gaps: 8/325 - (2%)

  Fly     4 NIRKVLVCDAVDKSCVELLEQHGIKVTYKLKLPVEELCQEVKNFDAAIVRSDTKITAEVLAAGSG 68
            |:||:|:.|::|..|.::|:..|::|..|..|..|||..|:::.:..||||.||:||:|:.|..
  Rat     5 NLRKILISDSLDPCCRKILQDGGLQVVEKQNLSKEELIAELQDCEGLIVRSATKVTADVINAAE- 68

  Fly    69 SLKVVGRAGAGVDNIDVPAATAQNVVVLNTPGGNSISACELTCILIGSLARPVVPAGQSMKEGRW 133
            .|:||||||.||||:|:.|||.:.|:|:|||.|||:||.||||.::..|||.:..|..|||:|:|
  Rat    69 KLQVVGRAGTGVDNVDLEAATRKGVLVMNTPNGNSLSAAELTCGMLMCLARQIPQATASMKDGKW 133

  Fly   134 DRKLYAGTELYGKTLAVLGLGRIGREVAIRMKTWGMRIIGYDPITTEAEAKAAGIEKMTLEEIWP 198
            |||.:.||||.||||.:|||||||||||.||:.:||:.:|||||.:...|.:.|::::.||||||
  Rat   134 DRKKFMGTELNGKTLGILGLGRIGREVAARMQAFGMKTVGYDPIISPEVAASFGVQQLPLEEIWP 198

  Fly   199 LADYITVHTPLIPATRNLISAETLAKCKQGVKVVNVARGGIIDEQAVLDGLESGKVAGAAFDVYP 263
            |.|:|||||||:|:|..|::..|.|:||:||:|||.|||||:||.|:|..|:||:.||||.||:.
  Rat   199 LCDFITVHTPLLPSTTGLLNDSTFAQCKKGVRVVNCARGGIVDEGALLRALQSGQCAGAALDVFT 263

  Fly   264 EEPPKSAVTKALISHPKVVATPHLGASTSEAQVRVAVEVAEQFIALNGTSPKYTSYAGVINKEAL 328
            ||||:.   :||:.|..|::.|||||||.|||.|...|:|.||:.:    .|..|..||:|.:||
  Rat   264 EEPPRD---RALVDHENVISCPHLGASTKEAQSRCGEEIAVQFVDM----VKGKSLTGVVNAQAL 321

  Fly   329  328
              Rat   322  321

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6287	NP_609496.1	PGDH_4	7..311	CDD:240650	163/303 (54%)
Phgdh	NP_113808.1	PGDH_4	8..310	CDD:240650	164/309 (53%)
		PGDH_inter	330..>407	CDD:437136