Protein Alignment CG6287 and CTBP2

DIOPT Version :10

• Sequence 1: NP_609496.1
• Gene: CG6287 / 34554
• FlyBaseID: FBgn0032350
• Length: 332
• Species: Drosophila melanogaster
• Sequence 2: NP_073713.2
• Gene: CTBP2 / 1488
• HGNCID: 2495
• Length: 985
• Species: Homo sapiens
• Alignment Length: 343
• Identity: 97/343 - (28%)
• Similarity: 166/343 - (48%)
• Gaps: 47/343 - (13%)

  Fly     1 MPL--NIRKVLVCDAVDKSCVE---LLEQHGIKVTYKLKLPVEELCQEVKNFDAAIVRSDTKITA 60
            ||:  ::..|..|||.....:.   |.|..|..:.:.:.|..|:|    :.|.|
Human   588 MPILKDLATVAFCDAQSTQEIHEKVLNEAVGAMMYHTITLTREDL----EKFKA----------- 637

  Fly    61 EVLAAGSGSLKVVGRAGAGVDNIDVPAATAQNVVVLNTPGGNSISACELTCILIGSLARPVVPAG 125
                     |:|:.|.|:|.||:|:.||....:.|.|.|........:.|...|.:|.|......
Human   638 ---------LRVIVRIGSGYDNVDIKAAGELGIAVCNIPSAAVEETADSTICHILNLYRRNTWLY 693

  Fly   126 QSMKEG------RWDRKLYAG-TELYGKTLAVLGLGRIGREVAIRMKTWGMRIIGYDPITTEAEA 183
            |:::||      ...|::.:| ..:.|:||.::|.||.|:.||:|.|.:|..:|.|||...:...
Human   694 QALREGTRVQSVEQIREVASGAARIRGETLGLIGFGRTGQAVAVRAKAFGFSVIFYDPYLQDGIE 758

  Fly   184 KAAGIEKM-TLEEIWPLADYITVHTPLIPATRNLISAETLAKCKQGVKVVNVARGGIIDEQAVLD 247
            ::.|:::: ||:::...:|.:::|..|.....:||:..|:.:.:||..:||.||||::||:|:..
Human   759 RSLGVQRVYTLQDLLYQSDCVSLHCNLNEHNHHLINDFTIKQMRQGAFLVNAARGGLVDEKALAQ 823

  Fly   248 GLESGKVAGAAFDVYPEEPPKSAVTKALISHPKVVATPHLGASTSEAQVRV----AVEVAEQFIA 308
            .|:.|::.|||.||: |..|.|.....|...|.::.|||....:.:|.:.:    |.|:..   |
Human   824 ALKEGRIRGAALDVH-ESEPFSFAQGPLKDAPNLICTPHTAWYSEQASLEMREAAATEIRR---A 884

  Fly   309 LNGTSPKYTSYAGVINKE 326
            :.|..|:  |....:|||
Human   885 ITGRIPE--SLRNCVNKE 900

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6287	NP_609496.1	PGDH_4	7..311	CDD:240650	89/318 (28%)
CTBP2	NP_073713.2	PHA03247	<109..572	CDD:223021
		PHA03377	<363..575	CDD:177614
		CtBP_dh	574..892	CDD:240624	93/333 (28%)