Protein Alignment Gyc32E and npr1b

DIOPT Version :9

• Sequence 1: NP_001097148.1
• Gene: Gyc32E / 34553
• FlyBaseID: FBgn0010197
• Length: 1191
• Species: Drosophila melanogaster
• Sequence 2: XP_009290669.2
• Gene: npr1b / 555911
• ZFINID: ZDB-GENE-100805-4
• Length: 1070
• Species: Danio rerio
• Alignment Length: 1135
• Identity: 398/1135 - (35%)
• Similarity: 596/1135 - (52%)
• Gaps: 141/1135 - (12%)

  Fly     5 CASAAAFSCILVLLLLGCQRSNPLAAGATVSSMRRLT--------------DTINIGFLAEYSQM 55
            |.|.:.| .:|.||||.|         .|:|:..:::              |.:....|.:::..
Zfish     6 CFSESRF-FLLPLLLLCC---------GTLSTWTKISKHQGSHKGAHNHSNDIVLAVILPQHNTS 60

  Fly    56 ------RVTLGGLPLAIEDVNKNPNLLPGKKL--AFKPVDIGHKMSAYRVKPLRAMTQMREAGVT 112
                  ||. ..|..||..||.||||||..::  .|...:....:.:..:.||.|:....|....
Zfish    61 YPWAWPRVG-PALDRAIARVNANPNLLPRHRVRHVFANSEDRDGICSESMAPLMAVDLKFEHNPW 124

  Fly   113 AFIGP--DESCTTEALLASAWNTPMLSFKCSDPIVS--NKSTFHTFARTLAPASKVSKSVISLLN 173
            |||||  |.:.:...|..:.|..||::  ...|.|:  ....:.:...|.....|:.:..:.|..
Zfish   125 AFIGPGCDYTSSPVGLFTAHWGLPMIT--AGAPAVAFLQMEIYTSITNTGPTHKKLGEYALHLYR 187

  Fly   174 AFHWNKFSIVVSSKPIWGSDVARAIQELAEARNFTISHFKYISDYIPTTKTLSQIDKIIEETYAT 238
            .|.||:.|:::.|....|.   ||.....|.. :|..|          .:.::.:|.:.||....
Zfish   188 HFGWNQHSLLMFSDTKMGE---RACYFALEGL-YTEMH----------EENITTMDLVFEENKGP 238

  Fly   239 TR----IYVFIGE-HIAMV----DFVRGL---QNRRLLESGDYIVVSVDDEIYDSNRRVNIMERN 291
            ..    ::...|: .:..|    |..|.|   .::..|...:|:...:|  |:..:.|....:
Zfish   239 VNYSELLHKIQGDGRVVFVCCSPDVFRQLIVHFHKAGLPKEEYVFFYID--IFGHSFRSRPSQ-- 299

  Fly   292 YLDPYIRKEKSKSLDKISFRSVIKISMTYPQNPHIRDICSKIKDYARKTPFLVPYHQRVFDNISV 356
               |:.|.:......|.:|:||..::...|||...:|..:.:|..|::.     ::..|.|::..
Zfish   300 ---PWARGDSDDVFAKEAFQSVKILTYLEPQNQEYKDFVTDLKSDAKRM-----FNFTVDDSLMN 356

  Fly   357 PIYGLHLYDSVMIYVRAITEVLRLGGDIYDGNLVMSHIFNRSYHSIQGFDVYIDSNGDAE----- 416
            .|.| ..||.:|:|..|:.|.|....:...|..|...::||:|:.:.|. |.||.|||.|
Zfish   357 IISG-GFYDGLMLYCHALNESLSDSHERPSGESVSKRMWNRTYYGVTGL-VQIDENGDRETDFAL 419

  Fly   417 --------GNYTVITLQNDVGSGASIGSLAKMSMQPVGFFAYDKNSVIPEFRYIKNDRPIQWLNG 473
                    |::.::.:.|        |:..:|::.|                    ...|||..|
Zfish   420 WDMADINTGDFQIVAVYN--------GTQKEMNILP--------------------GMAIQWPGG 456

  Fly   474 RPPLAEPLCGFHGE--LCPRKKLDWRYLVSGPLCALVVVV--AIALLIKHYRYEQTLAGLLWKVD 534
            :.|:..|.|||..|  .|..:.:....::|..|..:::::  ....:.:..:.|:.|...||::.
Zfish   457 KVPMDVPTCGFKNENPACRARTIAMHQMISIVLFLILIIIFTVTVFIYRKLKLEKELVAQLWRIS 521

  Fly   535 MKDVTVINLGEYNNPTNKNIFQICRQS---ILVVGEPNKRSFTNIALFRGNIVAMKKIHKKSVDI 596
            ..|:.:.:|.:....|...:....|.|   .|:..:.|.:.|.....|:|||||:|.|:::.|::
Zfish   522 WDDIQMSHLEKALRSTGSKLTLSLRGSNYGSLLTTDGNFQVFAKTGYFKGNIVAIKYINRRRVEL 586

  Fly   597 TRSIRKELKLMREVRHENIINFIGASTDHGSVIIFTTYCARGSLEDVLANEDLHLDHMFISSLVS 661
            ||.:..|||.||:|::|::..||||..|..::.|.|.||.||||:::|.|:.:.||.||..||:|
Zfish   587 TRKVLFELKHMRDVQNEHLTRFIGACIDPPNICIVTEYCPRGSLQNILENDSITLDWMFKYSLIS 651

  Fly   662 DILKGMIYLHDSEIISHGNLRSSNCLIDSRWVCQISDFGLHELKAGQEEPNKSELELKRALCMAP 726
            ||:|||.:||:|.|:|||||:||||::|:|:|.:|:|:||..::. :.:...:.....|.|.:||
Zfish   652 DIVKGMAFLHNSVIVSHGNLKSSNCVVDNRFVLKITDYGLSSIRT-ESDTEDAHSYYARKLWLAP 715

  Fly   727 ELLR-DAYRPGRGSQKGDVYSFGILLYEMIGRKGPW---GDTAYSKEEIIQFVKCPEMLQHGVFR 787
            ||.| :.:.|| |:||||||||||:|.|:..|:|.:   || ..|.:||:..|...|.   ...|
Zfish   716 ELSRMECFPPG-GTQKGDVYSFGIILQEVALRRGVFYLEGD-LLSPKEIVDRVALGEW---PYLR 775

  Fly   788 PALT-HTHLDIPDYIRKCLCQCWDEDPEVRPDIRLVRMHLKELQAGLKPNIFDNMLSIMEKYAYN 851
            |:|. ..|   .:.:.:.:.:||.|:|..||:...:.:.|::.....:.||.||:||.||:||.|
Zfish   776 PSLNPQAH---SEELGQLMQRCWAEEPSDRPEFSHISVLLRKQNREHRSNILDNLLSRMEQYANN 837

  Fly   852 LEGLVQERTNLLYEEKKKTDMLLYQMLPRPVAELLKRGDPVEAECFDCVTILFSDIVGFTELCTT 916
            ||.||:|||....|||:|.:.||||:||..|||.||||:.|:||.||.|||.||||||||.|...
Zfish   838 LEELVEERTQAYLEEKRKAEALLYQILPHSVAEQLKRGETVQAEAFDSVTIYFSDIVGFTSLSAE 902

  Fly   917 STPFEVVEMLNDWYTCCDSIISNYDVYKVETIGDAYMVVSGLPLQNGSRHAGEIASLALHLLETV 981
            |||.:||.:|||.|||.|:||.|:|||||||||||||||||||::||..|..|||.::|.|||.|
Zfish   903 STPLQVVTLLNDLYTCFDAIIDNFDVYKVETIGDAYMVVSGLPVRNGKLHGREIARMSLALLEAV 967

  Fly   982 GNLKIRHKPTETVQLRIGVHSGPCAAGVVGQKMPRYCLFGDTVNTASRMESTGDSMRIHISEATY 1046
            ...||||:|.|.::||||:||||..|||||.||||||||||||||:|||||.|:.::||:|.||.
Zfish   968 KTFKIRHRPDEQLKLRIGIHSGPVCAGVVGLKMPRYCLFGDTVNTSSRMESNGEPLKIHVSSATR 1032

  Fly  1047 QLLQVIGSYVCIERGLTSIKGKGDMRTYWL 1076
            .:||....:....||...:||||.||||||
Zfish  1033 AVLQEFNCFQLELRGDVEMKGKGKMRTYWL 1062

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gyc32E	NP_001097148.1	PBP1_Speract_GC_like	44..448	CDD:107365	99/440 (23%)
		ANF_receptor	59..427	CDD:279440	92/398 (23%)
		PHA02988	534..826	CDD:165291	114/299 (38%)
		PK_GC-A_B	550..832	CDD:270944	113/289 (39%)
		HNOBA	<847..886	CDD:285003	23/38 (61%)
		CYCc	865..1057	CDD:214485	125/191 (65%)
		Guanylate_cyc	892..1076	CDD:278633	118/183 (64%)
npr1b	XP_009290669.2	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D123766at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100944
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.720