DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gyc32E and ACXB

DIOPT Version :9

Sequence 1:	NP_001097148.1	Gene:	Gyc32E / 34553	FlyBaseID:	FBgn0010197	Length:	1191	Species:	Drosophila melanogaster
Sequence 2:	NP_620474.2	Gene:	ACXB / 53427	FlyBaseID:	FBgn0040509	Length:	1114	Species:	Drosophila melanogaster

Alignment Length:	407	Identity:	102/407 - (25%)
Similarity:	162/407 - (39%)	Gaps:	118/407 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   842 LSIMEKYAYNLEGL-------------VQERTNLLYEE------KKKTDMLLYQMLP----RPVA 883
            :.|.....:||.|:             ..:|...|.||      :::..|||..:||    :|:.
  Fly   206 VDIFHYLGFNLMGIFFRIMNDTMVRSSFLDRHQFLKEEMWLRQARQQESMLLDSILPPQIAKPIQ 270

  Fly   884 ELLKR--------GDPV-----EAECFDC------VTILFSDIVGFTELCTTSTPFEVVEMLNDW 929
            :.:|.        .|.:     ..|.|..      |:||::|:|.:|.|.||.|..::|::|:|.
  Fly   271 QSIKERIMLSETDSDRIVVNARRTENFMAIQIHPDVSILYADVVNYTHLTTTLTVEKLVKVLHDL 335

  Fly   930 YTCCDSIISNYDVYKVETIGDAYMVVSGLPLQNGSRHAGEIASLALHLLETVGNLKIRHKPTETV 994
            |...|...|.:.|.:::.:||.|..|:||. :....||....||.:.::..:..:: .|:..: :
  Fly   336 YGRFDMAASTFKVQRIKFLGDCYYCVAGLG-EADPDHARMAVSLGISMIANIQEVR-AHRALD-I 397

  Fly   995 QLRIGVHSGPCAAGVVGQKMPRYCLFGDTVNTASRMESTGDSMRIHISEATYQLLQVI------G 1053
            .:|||||||...|||:||...:|.::|..|:.|:|:|:||....:|:|..|...|.|.      |
  Fly   398 DMRIGVHSGTLLAGVIGQAKLQYDIWGPDVDIANRLEATGKPGYVHVSGRTLSSLNVAEYTVFPG 462

  Fly  1054 SYVCIERGLTSIKGKGDMRTYWLT---------------------------KRQQPELTPDLIST 1091
            :.|...   ..|..|..|.||.||                           .|:.|.|.|.|:|
  Fly   463 TEVAQS---DPILQKQPMTTYLLTAAPSRNSVRSVDAVHSYAEIDINALGASRKSPILRPTLMS- 523

  Fly  1092 VDTLDTYCSGPRESMEVSVHQYCSPASNNYRLGSCNCDTKCLYSRRSDDNVTNSHGTSEFPKVSE 1156
             |.|       ||..:            ...:|..|..:.|.....:|:.|  :||...|
  Fly   524 -DEL-------REEFK------------KMPVGGFNIRSPCCRDNSNDEKV--NHGLGMF----- 561

  Fly  1157 PAQVNCNQLCVCRLNSS 1173
                     ||...:||
  Fly   562 ---------CVAFKDSS 569

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gyc32E	NP_001097148.1	PBP1_Speract_GC_like	44..448	CDD:107365
		ANF_receptor	59..427	CDD:279440
		PHA02988	534..826	CDD:165291
		PK_GC-A_B	550..832	CDD:270944
		HNOBA	<847..886	CDD:285003	13/61 (21%)
		CYCc	865..1057	CDD:214485	66/226 (29%)
		Guanylate_cyc	892..1076	CDD:278633	62/200 (31%)
ACXB	NP_620474.2	AC_N	<36..276	CDD:292831	15/69 (22%)
		CYCc	249..459	CDD:214485	63/212 (30%)
		Nucleotidyl_cyc_III	298..484	CDD:299850	61/191 (32%)
		CYCc	825..1047	CDD:214485
		Nucleotidyl_cyc_III	853..1072	CDD:299850
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45453890
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740