DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gyc32E and Ac76E

DIOPT Version :9

Sequence 1:	NP_001097148.1	Gene:	Gyc32E / 34553	FlyBaseID:	FBgn0010197	Length:	1191	Species:	Drosophila melanogaster
Sequence 2:	NP_001246838.1	Gene:	Ac76E / 40180	FlyBaseID:	FBgn0004852	Length:	1312	Species:	Drosophila melanogaster

Alignment Length:	280	Identity:	79/280 - (28%)
Similarity:	135/280 - (48%)	Gaps:	54/280 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   841 MLSIMEKYAYNLEGLVQERTNLLYEEKKKTD------------MLLYQMLPRPVAE---LLKRGD 890
            ::.|:..:..:.:|....||:.|::.|.|.:            :||..:||..||.   .|:|..
  Fly  1035 LVIILVLHTLDRQGEYVARTDFLWKAKLKVEQEEVETMRGINKILLENILPAHVATHFLHLERST 1099

  Fly   891 PVEAECFDCVTILFSDIVGFTELC----TTSTPFEVVEMLNDWYTCCDSIISNYD---------- 941
            .:..|.:.||.::|:.|..:.|..    ......|.:.:||:       ||.::|
  Fly  1100 ELYHESYSCVAVMFASIPNYKEFYDETDVNKQGLECLRLLNE-------IICDFDKLLLKPKFSG 1157

  Fly   942 VYKVETIGDAYMVVSGL--PLQNG--SRHAGE-----------IASLALHLLETVGNLKIRHKPT 991
            :.|::||...||..|||  ..::|  ||...:           :...|:.|:..:.:  |..:..
  Fly  1158 IEKIKTIASTYMCASGLRPGKEDGATSRSFADEKRTEEHNVVILVEFAIALMSILDS--INRESF 1220

  Fly   992 ETVQLRIGVHSGPCAAGVVGQKMPRYCLFGDTVNTASRMESTGDSMRIHISEATYQLLQVIGSYV 1056
            :..:||||::.||..|||:|.:.|:|.::.:|||.||||:|.|...|:..:|.|.::|...| |.
  Fly  1221 QRFRLRIGLNHGPVIAGVIGAQKPQYDIWSNTVNVASRMDSCGVMGRLQTTENTAKILMTAG-YE 1284

  Fly  1057 CIERGLTSIKGKGDMRTYWL 1076
            |..||||.:||||::.||::
  Fly  1285 CECRGLTYVKGKGNLVTYFV 1304

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gyc32E	NP_001097148.1	PBP1_Speract_GC_like	44..448	CDD:107365
		ANF_receptor	59..427	CDD:279440
		PHA02988	534..826	CDD:165291
		PK_GC-A_B	550..832	CDD:270944
		HNOBA	<847..886	CDD:285003	12/53 (23%)
		CYCc	865..1057	CDD:214485	63/235 (27%)
		Guanylate_cyc	892..1076	CDD:278633	64/212 (30%)
Ac76E	NP_001246838.1	AC_N	<67..289	CDD:292831
		CYCc	259..467	CDD:214485
		Guanylate_cyc	311..469	CDD:278633
		BASP1	510..667	CDD:283191
		CYCc	1079..1283	CDD:214485	60/213 (28%)
		Guanylate_cyc	1101..1305	CDD:278633	64/214 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45453904
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740