DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Gyc32E and Ac13E

DIOPT Version :9

Sequence 1:	NP_001097148.1	Gene:	Gyc32E / 34553	FlyBaseID:	FBgn0010197	Length:	1191	Species:	Drosophila melanogaster
Sequence 2:	NP_001259575.1	Gene:	Ac13E / 32485	FlyBaseID:	FBgn0022710	Length:	1703	Species:	Drosophila melanogaster

Alignment Length:	315	Identity:	87/315 - (27%)
Similarity:	146/315 - (46%)	Gaps:	54/315 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   812 DPEVRPDIRLVRMHLKELQAGLKPNIFD--NMLSIMEKYAYNLEGLVQERTNLLYEEKKKTDMLL 874
            ||..|..|..:..||.....|:...|.:  .|.....|...||  ||:.:..:   ||:..:.::
  Fly   252 DPSNRILILRIMAHLSVHLVGVHVLIMNLVRMRGTFMKVGQNL--LVRRQLEM---EKQLKEKMI 311

  Fly   875 YQMLPRPVAE-LLKRGD-----------------------------PVEAECFDCVTILFSDIVG 909
            :.::|..||: ||..|.                             |......:.|:|||:||||
  Fly   312 HSVMPPKVADMLLNEGGPSGLDAGGLPPESHYMRPRASNDVKSLFRPFHMHSMENVSILFADIVG 376

  Fly   910 FTELCTTSTPFEVVEMLNDWYTCCDSIISNYDVYKVETIGDAYMVVSGLPLQNGSRHAGEIASLA 974
            ||.:.:|.|..::||:|||.:...|.:.|.....|:.|:||.|..|||.| :..:.||.....:.
  Fly   377 FTRMSSTKTAEQLVEILNDLFERFDDLCSLSGCEKISTLGDCYYCVSGCP-EPRADHAICCVEMG 440

  Fly   975 LHLLETVGNLKI-RHKPTETVQLRIGVHSGPCAAGVVGQKMPRYCLFGDTVNTASRMESTGDSMR 1038
            |.:::.:..... ||   |.|::|:|||:|....|:||.:..::.::.:.|:.|::|||:|...:
  Fly   441 LGMIDAMRCFDAQRH---EGVKMRVGVHTGTVLCGIVGTRRVKFDVWSNDVSLANKMESSGKPEQ 502

  Fly  1039 IHISEATYQLLQVIGSYVCIERGLTSIKGKGDMRTYWLTKRQQP-----ELTPDL 1088
            :|||:.|...|   |....:|.| ..:.|.   |||::..|::.     .|:|.:
  Fly   503 VHISQETSSFL---GDAYYLEEG-EEVFGH---RTYFVVGRRRDFTRTNSLSPSM 550

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gyc32E	NP_001097148.1	PBP1_Speract_GC_like	44..448	CDD:107365
		ANF_receptor	59..427	CDD:279440
		PHA02988	534..826	CDD:165291	4/13 (31%)
		PK_GC-A_B	550..832	CDD:270944	6/19 (32%)
		HNOBA	<847..886	CDD:285003	10/39 (26%)
		CYCc	865..1057	CDD:214485	64/222 (29%)
		Guanylate_cyc	892..1076	CDD:278633	61/184 (33%)
Ac13E	NP_001259575.1	CYCc	302..518	CDD:214485	64/225 (28%)
		Guanylate_cyc	361..535	CDD:278633	61/184 (33%)
		CYCc	1362..1556	CDD:214485
		Guanylate_cyc	1388..1575	CDD:278633
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45453895
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740