Protein Alignment Gyc32E and CG32305

DIOPT Version :9

• Sequence 1: NP_001097148.1
• Gene: Gyc32E / 34553
• FlyBaseID: FBgn0010197
• Length: 1191
• Species: Drosophila melanogaster
• Sequence 2: NP_728725.2
• Gene: CG32305 / 317967
• FlyBaseID: FBgn0052305
• Length: 1164
• Species: Drosophila melanogaster
• Alignment Length: 1153
• Identity: 213/1153 - (18%)
• Similarity: 377/1153 - (32%)
• Gaps: 438/1153 - (37%)

  Fly   211 HFKYISDYIPTTKTLSQIDKIIEETYATTRIYVF-IGEHIAMVDFVRGLQNRRLLESGDYIVVSV 274
            :.:|::|         |:...:..:||   ||:| :....:....:|....||.:.|
  Fly   186 YMQYLND---------QVSFYLLASYA---IYLFTLNLIFSFFTIIRDYGLRRAILS-------- 230

  Fly   275 DDEIYDSNRRVNIMERNYLDPYIRKEKSKSLDKISFRSVIKISMTYPQNPHIRDICSKIKDYARK 339
                     |..::.:|.:...:.|:::..|:.|..|.:|:...        .:|||:|:|..:.
  Fly   231 ---------RYQLVYQNIVYQLVMKKENGLLESILPRKMIRTLQ--------EEICSRIEDQDKN 278

  Fly   340 -TP--------FLVPYHQRVFDNISVPIYGLHLYDSVMIYVRA--ITEVLRLGGDIY-------D 386
             ||        ||.||     .|:|:.:..:..|..:...:.|  :.|:|.   |::       :
  Fly   279 FTPSKAGLRKLFLEPY-----PNVSILVADMVNYTHLTTTLEAPQLVEILH---DLFVNFDLAAN 335

  Fly   387 GNLVMSHIF-NRSYHSIQGFDVYIDSNGD--AEGNYTVITLQNDVGSGASIGSLAKMSMQPVGFF 448
            .|..|...| ..||:.:.|...|..::..  .:....:|.:...|.|...:....::.:.....|
  Fly   336 RNRAMRIKFLGDSYNCVAGIPNYFPAHASCCVDQALEMIHITQGVSSRRELDINLRIGVHSGEVF 400

  Fly   449 AYDKNSVIPEFRYIKNDRPIQWLNGRPPLAEPLCGFHGELCPRKKLDWRY------------LVS 501
            |                                 |..|.      ..|::            |.|
  Fly   401 A---------------------------------GIIGH------TKWQFDIWSKDVDITNRLES 426

  Fly   502 GPLCALVVVV--AIALLIKHYRY-EQTLAG----LLWKVDMKDVTVINL-------GEYNNPTNK 552
            ..|..||.|.  .:::|.:||.: |.|.|.    :|.:..::...|.|.       ||.::..:.
  Fly   427 SGLPGLVHVSQRTLSMLDEHYIFREGTEAAKNDPILQQAGIRTFLVSNRLPDAVEPGELDDELSS 491

  Fly   553 NIFQICRQSI---------------------LVVG----------EPNKRSFTNIALFRGNIVAM 586
            .....||.|.                     :.||          ...|:.|....||...|..:
  Fly   492 ASINSCRLSYGGYYEEIQIKAQREIMKEVDQMAVGHCFIEWRRSSSMKKQDFNEEYLFSNQIHLV 556

  Fly   587 KKIHKKSVDITRSIRKE---------------------------LKLMREVRHENIINFIGASTD 624
                   :.:.||.::|                           :.|:.|..:.:|:..:|.
  Fly   557 -------LGVFRSWKREWEFHNLPDLMIKYTMLLVLCAGLAIMSINLIEEATYPDILVLLGI--- 611

  Fly   625 HGSVIIFTTYCARGSLEDVLAN-EDLHLDHMFISSLVSDILKGMIYLHDSEIISHGNLRSSNCLI 688
               ::|....|       :||. :.|.|....::.                      :...:|.:
  Fly   612 ---LLILLILC-------ILAGYKKLRLQWKKLTP----------------------MSQPSCFL 644

  Fly   689 DSRWVCQISDFGLHELKAGQEEPNKSELELKRALCMAPELLRDAYRPGRGSQKGDVYS------- 746
             |||:.:||            |..:..|.::..|.|...||...    ..||.  |:|
  Fly   645 -SRWLLRIS------------ERIEDSLFVRIPLTMVVLLLLYV----MSSQA--VFSCDVAKLE 690

  Fly   747 FGILLYEMIGRK------GPWGDTAYSKEEIIQFV----KCPEMLQHGVFRPALTHTHLDIPDYI 801
            ..|:...:...|      |||..| |....:|..:    .||.::
  Fly   691 LSIIEAHLYNEKSYAECFGPWTVT-YCVVIVISLLFVVPGCPLVI-------------------- 734

  Fly   802 RKCLCQCWDEDPEVRPDIRLVRMHL--------------KELQAGLKPN---------------I 837
                        ::...:.::.:||              :....|||.:               :
  Fly   735 ------------KILAGLLILGLHLGTVHLYYGFAFERSETTDLGLKSDYAHTWYLVALFIVLVL 787

  Fly   838 FDNMLSIMEKYAYNLEGLVQERTNLLYEEKKKTDMLLYQMLPRPVAELLK---RGDPVEAECFDC 899
            .:..::.:.|:.|.:....:|......|:.:...:::..:||..||::.|   ..|.:..|.|..
  Fly   788 RERHVNYLRKFNYFMRVCYEEAHQQTDEKLRSIKIIMANILPTHVAQVYKVRRPHDQLYYENFSK 852

  Fly   900 VTILFSDIVGFTELCTTSTPFEVVEMLNDWYTCCDSIISNYDV-YKVETI---GDAYMVVSGL-- 958
            |.::|:.|..|      :.....:.:|::...|.|.::.:|.. ||:|.|   |..|||..||
  Fly   853 VAVMFASIENF------NADTAGLRILHEIICCFDDLLVDYQTRYKIEKIKVMGWTYMVACGLET 911

  Fly   959 -------------------PLQNGSR----HAG--------------------EIASL-----AL 975
                               .::.||.    |.|                    ::|.|     ||
  Fly   912 DHYTDFSIDIPVKQPEADSEIRRGSSVLTVHFGSTEDDEMSGDNVSQPYAQVQDVAVLVMTEFAL 976

  Fly   976 HLLETVGNLKIRHKPTE-----TVQLRIGVHSGPCAAGVVGQKMPRYCLFGDTVNTASRMESTGD 1035
            .||..:.:::..:..:|     |..|:||:..|...|||||...|.|.::|.|||.||||.|||.
  Fly   977 DLLRIMHDIRYNYVFSEYDTFLTGSLKIGISHGSVMAGVVGLSKPHYDIWGHTVNMASRMSSTGL 1041

  Fly  1036 SMRIHISEATYQLLQVIGSYVCIERGLTSIKGKGDMRTYWLTKRQQPELT---PDLIS------- 1090
            ...|.::..|.::|:.. :..|..||.|.:||.|.:.||.:.  ..|:||   .|.:|
  Fly  1042 LDNIQVTRHTAKVLRQF-NIRCNYRGHTEVKGVGKVPTYLVV--VDPDLTFQDHDQVSMSMKDSK 1103

  Fly  1091 --TVDTL-----------------DTYCSGPRE-------SMEVSVHQ 1112
              .:|||                 :....|..|       .:|||:|:
  Fly  1104 SWVIDTLSLSFTPSFVPPKSSTSDEEEAEGELEENVSEGDELEVSIHE 1151

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gyc32E	NP_001097148.1	PBP1_Speract_GC_like	44..448	CDD:107365	47/258 (18%)
		ANF_receptor	59..427	CDD:279440	45/237 (19%)
		PHA02988	534..826	CDD:165291	53/374 (14%)
		PK_GC-A_B	550..832	CDD:270944	51/371 (14%)
		HNOBA	<847..886	CDD:285003	8/38 (21%)
		CYCc	865..1057	CDD:214485	64/253 (25%)
		Guanylate_cyc	892..1076	CDD:278633	66/242 (27%)
CG32305	NP_728725.2	CYCc	251..449	CDD:214485	46/252 (18%)
		Nucleotidyl_cyc_III	292..445	CDD:299850	31/199 (16%)
		CYCc	814..1056	CDD:214485	63/247 (26%)
		Nucleotidyl_cyc_III	845..1081	CDD:299850	66/242 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45453887
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740