Protein Alignment Gyc32E and Adcy10

DIOPT Version :9

• Sequence 1: NP_001097148.1
• Gene: Gyc32E / 34553
• FlyBaseID: FBgn0010197
• Length: 1191
• Species: Drosophila melanogaster
• Sequence 2: NP_766617.2
• Gene: Adcy10 / 271639
• MGIID: 2660854
• Length: 1614
• Species: Mus musculus
• Alignment Length: 543
• Identity: 101/543 - (18%)
• Similarity: 189/543 - (34%)
• Gaps: 206/543 - (37%)

  Fly   528 GLLWKVDMKDVTVI----NLGEYNNPTNKNIFQICRQSILVVGEPNKRSFTNIALFRGNI----- 583
            |:|..||:...|.:    :...|.:...:.:.:|....|..:.|       .:.:|.|:|
Mouse    41 GVLMFVDISGFTAMTEKFSTAMYMDRGAEQLVEILNYYISAIVE-------KVLIFGGDILKFAG 98

  Fly   584 ---VAMKKIHKKSVD--ITRSIRKELKL--MREVRHE----NIINFIGASTDHGSVIIFTTYCAR 637
               :|:.|:.:|.:.  ||..|:..|::  :.|.:..    :|...||.:..|.::::|
Mouse    99 DALLALWKVERKQLKNIITVVIKCSLEIHGLFEAKEAEEGLDIRVKIGLAAGHITMLVF------ 157

  Fly   638 GSLEDVLANEDLHLDHMFISSLVSDI--LKGMIYLHDSEIISHGNLRSSNCLIDSRWVCQISDFG 700
                    .::.....:.|...|.|:  .:.|..::|.       :.|.||     |  |:.|
Mouse   158 --------GDETRNYFLVIGQAVDDVRLAQNMAQMNDV-------ILSPNC-----W--QLCD-- 198

  Fly   701 LHELKAGQEEPNKSELELKRALCMAPELLRDAYRPGRGSQKGDVYSFGILLYEMIGRKGPWGDTA 765
                        :|.:|::|    .|:            |:....||         .|.|   ..
Mouse   199 ------------RSMIEIER----IPD------------QRAVKVSF---------LKPP---PT 223

  Fly   766 YSKEEIIQFVKCPEMLQHGVFRPALTHTHLDIPDYIR-KCLCQCWDEDPEVRPDIR--LVRMHLK 827
            ::.:|.  |.||...:.   :.|:..|     .:::| .|:.   :.|||:...::  ::.:.||
Mouse   224 FNFDEF--FTKCMGFMD---YYPSGDH-----KNFLRLACML---ESDPELELSLQKYVMEIILK 275

  Fly   828 ELQAGLKPNIFDNMLSIMEKYAYNLEGLVQERTNLLYEEKKKTDMLLYQMLPRPVAELLKRGDPV 892
            ::.        |..|   ..|...|..:.....||:::|:.|.:::               |..:
Mouse   276 QID--------DKQL---RGYLSELRPVTIVFVNLMFKEQDKVEVI---------------GSAI 314

  Fly   893 EAECFDCVTIL------FSDIVGFTELCTTSTPFEVVEMLNDWYTCCDSIISNYDVYKVETIGDA 951
            :|.|....::|      .:.:..|.:.|                                    :
Mouse   315 QAACVHITSVLKVFRGQINKVFMFDKGC------------------------------------S 343

  Fly   952 YMVVSGLPLQNGSRHAGEIASLALHLLETVGNL--------KIRHKPTETVQLRIGVHSGPCAAG 1008
            ::.|.|.|   |.:...||.    |.||:..::        |||     ||.  |||.||....|
Mouse   344 FLCVFGFP---GEKAPDEIT----HALESAVDIFDFCSQVHKIR-----TVS--IGVASGIVFCG 394

  Fly  1009 VVGQKM-PRYCLFGDTVNTASRM 1030
            :||..: ..|.:.|..||.|:||
Mouse   395 IVGHTVRHEYTVIGQKVNIAARM 417

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gyc32E	NP_001097148.1	PBP1_Speract_GC_like	44..448	CDD:107365
		ANF_receptor	59..427	CDD:279440
		PHA02988	534..826	CDD:165291	53/316 (17%)
		PK_GC-A_B	550..832	CDD:270944	52/302 (17%)
		HNOBA	<847..886	CDD:285003	6/38 (16%)
		CYCc	865..1057	CDD:214485	37/181 (20%)
		Guanylate_cyc	892..1076	CDD:278633	34/154 (22%)
Adcy10	NP_766617.2	CHD	40..214	CDD:143636	41/237 (17%)
		CHD	292..461	CDD:143636	39/191 (20%)
		COG3899	485..>959	CDD:226415

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900