DRSC/TRiP Functional Genomics Resources

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Protein Alignment Gyc32E and Gucy1a2

DIOPT Version :9

Sequence 1:NP_001097148.1 Gene:Gyc32E / 34553 FlyBaseID:FBgn0010197 Length:1191 Species:Drosophila melanogaster
Sequence 2:NP_001028494.1 Gene:Gucy1a2 / 234889 MGIID:2660877 Length:730 Species:Mus musculus


Alignment Length:314 Identity:124/314 - (39%)
Similarity:163/314 - (51%) Gaps:44/314 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly   776 KCPEMLQHGVFRPALTHTHL-DIPDYIRKCLCQCWDEDPEVRPDIRLVRMHLKELQAGLKPNIFD 839
            |..|::..|:        || |||.:             :...|:.||....| .|.|||..   
Mouse   427 KLDELMGRGL--------HLSDIPIH-------------DATRDVILVGEQAK-AQDGLKKR--- 466

  Fly   840 NMLSIMEKYAYNLEGLVQERTN-LLYEEKKKTDMLLYQMLPRPVAELLKRGDPVEAECFDCVTIL 903
                 |:|....|     |||: .|.||||||..|||.:.|..||:.|.:|..|:|..||.||:|
Mouse   467 -----MDKLKATL-----ERTHQALEEEKKKTVDLLYSIFPGDVAQQLWQGQQVQARKFDDVTML 521

  Fly   904 FSDIVGFTELCTTSTPFEVVEMLNDWYTCCDSIISNYDVYKVETIGDAYMVVSGLPLQNGSRHAG 968
            ||||||||.:|...||.:|:.|||:.||..|......|:||||||||||.|.|||. :....||.
Mouse   522 FSDIVGFTAICAQCTPMQVISMLNELYTRFDHQCGLLDIYKVETIGDAYCVASGLH-RKSLCHAK 585

  Fly   969 EIASLALHLLETVGNLKIRHKPTETVQLRIGVHSGPCAAGVVGQKMPRYCLFGDTVNTASRMEST 1033
            .||.:||.::|.  :.::.....:.:|:|||:|||...|||||.:||||||||:.|..||:.||.
Mouse   586 PIALMALKMMEL--SEEVLTPDGKAIQMRIGIHSGSVLAGVVGVRMPRYCLFGNNVTLASKFESG 648

  Fly  1034 GDSMRIHISEATYQLLQVIGSYVCIERGLTSIKGKGDMR----TYWLTKRQQPE 1083
            ....||::|..|||||:...|:..|.|....:.......    .|:|..|..|:
Mouse   649 SHPRRINVSPTTYQLLKREDSFTFIPRSREELPDNFPKEIPGVCYFLELRTDPK 702

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Gyc32ENP_001097148.1 PBP1_Speract_GC_like 44..448 CDD:107365
ANF_receptor 59..427 CDD:279440
PHA02988 534..826 CDD:165291 11/50 (22%)
PK_GC-A_B 550..832 CDD:270944 13/56 (23%)
HNOBA <847..886 CDD:285003 18/39 (46%)
CYCc 865..1057 CDD:214485 95/191 (50%)
Guanylate_cyc 892..1076 CDD:278633 84/187 (45%)
Gucy1a2NP_001028494.1 HNOB <157..268 CDD:285002
HNOBA 314..501 CDD:285003 33/108 (31%)
CYCc 483..672 CDD:214485 95/191 (50%)
Guanylate_cyc 512..696 CDD:278633 83/186 (45%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG2114
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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