Protein Alignment Gyc32E and Gucy1a2

DIOPT Version :10

• Sequence 1: NP_001097148.1
• Gene: Gyc32E / 34553
• FlyBaseID: FBgn0010197
• Length: 1191
• Species: Drosophila melanogaster
• Sequence 2: NP_001028494.1
• Gene: Gucy1a2 / 234889
• MGIID: 2660877
• Length: 730
• Species: Mus musculus
• Alignment Length: 314
• Identity: 124/314 - (39%)
• Similarity: 163/314 - (51%)
• Gaps: 44/314 - (14%)

  Fly   776 KCPEMLQHGVFRPALTHTHL-DIPDYIRKCLCQCWDEDPEVRPDIRLVRMHLKELQAGLKPNIFD 839
            |..|::..|:        || |||.:             :...|:.||....| .|.|||..
Mouse   427 KLDELMGRGL--------HLSDIPIH-------------DATRDVILVGEQAK-AQDGLKKR--- 466

  Fly   840 NMLSIMEKYAYNLEGLVQERTN-LLYEEKKKTDMLLYQMLPRPVAELLKRGDPVEAECFDCVTIL 903
                 |:|....|     |||: .|.||||||..|||.:.|..||:.|.:|..|:|..||.||:|
Mouse   467 -----MDKLKATL-----ERTHQALEEEKKKTVDLLYSIFPGDVAQQLWQGQQVQARKFDDVTML 521

  Fly   904 FSDIVGFTELCTTSTPFEVVEMLNDWYTCCDSIISNYDVYKVETIGDAYMVVSGLPLQNGSRHAG 968
            ||||||||.:|...||.:|:.|||:.||..|......|:||||||||||.|.|||. :....||.
Mouse   522 FSDIVGFTAICAQCTPMQVISMLNELYTRFDHQCGLLDIYKVETIGDAYCVASGLH-RKSLCHAK 585

  Fly   969 EIASLALHLLETVGNLKIRHKPTETVQLRIGVHSGPCAAGVVGQKMPRYCLFGDTVNTASRMEST 1033
            .||.:||.::|.  :.::.....:.:|:|||:|||...|||||.:||||||||:.|..||:.||.
Mouse   586 PIALMALKMMEL--SEEVLTPDGKAIQMRIGIHSGSVLAGVVGVRMPRYCLFGNNVTLASKFESG 648

  Fly  1034 GDSMRIHISEATYQLLQVIGSYVCIERGLTSIKGKGDMR----TYWLTKRQQPE 1083
            ....||::|..|||||:...|:..|.|....:.......    .|:|..|..|:
Mouse   649 SHPRRINVSPTTYQLLKREDSFTFIPRSREELPDNFPKEIPGVCYFLELRTDPK 702

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gyc32E	NP_001097148.1	PBP1_SAP_GC-like	44..448	CDD:380593
		PK_GC-A_B	550..832	CDD:270944	13/56 (23%)
		CYCc	865..1057	CDD:214485	95/191 (50%)
Gucy1a2	NP_001028494.1	HNOB	<157..268	CDD:462233
		HNOBA	314..501	CDD:462234	33/108 (31%)
		Guanylate_cyc	512..696	CDD:425528	83/186 (45%)