Protein Alignment Gyc32E and gcy-34

DIOPT Version :10

• Sequence 1: NP_001097148.1
• Gene: Gyc32E / 34553
• FlyBaseID: FBgn0010197
• Length: 1191
• Species: Drosophila melanogaster
• Sequence 2: NP_506319.1
• Gene: gcy-34 / 191656
• WormBaseID: WBGene00001554
• Length: 686
• Species: Caenorhabditis elegans
• Alignment Length: 805
• Identity: 191/805 - (23%)
• Similarity: 318/805 - (39%)
• Gaps: 202/805 - (25%)

  Fly   362 HLYDSVMIY--VRAITEVLRLGGD----IYDGNLVMSHIFNRSYHSIQGFDVYIDSNGDAEGNYT 420
            |.|.....|  |.:::.||::..|    :|.|.|:       :|....|:|..:.|..
 Worm    41 HYYSDTDTYVLVDSVSIVLKVTKDQIWEMYGGFLI-------TYSMEIGWDELVRSMS------- 91

  Fly   421 VITLQNDVGSGASIGSLAKMSMQPVGFFAYDKNSVIPEFRYIKNDRP-----IQWLNGRPPLAEP 480
                .|..|...::.||...    :....|..|...|.||..:|  |     :.:..|||.|
 Worm    92 ----PNLKGFLDNLDSLHYF----IDHVVYKANLRGPSFRCEEN--PDGTLMLHYFTGRPGL--- 143

  Fly   481 LCGFHGELCPRKKLDWRYLVSGPLCALVVVVAIALLIKHYRYEQTLAGLLWKVDMKDVTVINLGE 545
               :|             :|.|      ||..:|.|:.:.                |::::..|.
 Worm   144 ---YH-------------IVKG------VVKEVAKLVFNL----------------DISLVVQGR 170

  Fly   546 YNNPTNKNIFQICRQSILV----VGEPNKRSFTNIALFRGNIVAMKKIHKKSVDITRSIRKELKL 606
            .....:.|..:...:.::.    |.||.:.|.|:      ...|:..:..   |....|...||:
 Worm   171 TQRSVHMNNGERVEEHVIFLIKNVEEPRRDSDTS------TTSALTSVEP---DFGEIIDDNLKV 226

  Fly   607 MREVRHENIINFIGASTDHGSVIIFTTYCARGSLEDVLANEDLHLDHMFISS-----LVSDILKG 666
                   ::.:|..|...|   .:....|......|.|.|   |:.:..:..     .:.:|.:.
 Worm   227 -------SLQDFSRALPYH---FVLDESCRLVQCGDELYN---HIPNELLQPGTPILRIFEINRP 278

  Fly   667 MIYLHDSEIISHGNLRSSNCLIDSRWVCQISDFGLHE--LKAGQEEPNKSELELKRALCMAPELL 729
            .|.| |.|.|.:        .|::.:|.|:....|.:  :.|..:|..:.|:|.......:.||.
 Worm   279 QIPL-DFENICN--------FINAVFVLQVKTSPLRKKHMNAMTKEEREQEVEAMEEEVESNELT 334

  Fly   730 RDAYRPGRGSQKGDVYSFGILLYEMIGRKGPWGDTAYSKEEIIQFVKCP------EMLQHGVFRP 788
            :..:...:|...            |:.          :|:.|| ::..|      |::|.|
 Worm   335 QGCHLKLKGQMM------------MLS----------TKKHII-YLCSPYVTSINELMQFG---- 372

  Fly   789 ALTHTHLDIPDYIRKCLCQCWDEDPEVRPDIRLVRMHLKELQAGLKPNIFDNMLSIMEKYAYNLE 853
             :..|.:.:.|..|..              |.|.:..|.:::..|:....:..|..|
 Worm   373 -MRLTAMPLHDATRDL--------------ILLNQQRLSDVEVNLQLEANNEQLETM-------- 414

  Fly   854 GLVQERTNLLYEEKKKTDMLLYQMLPRPVAELLKRGDPVEAECFDCVTILFSDIVGFTELCTTST 918
                  |:.|..|::|||.:|..||||.:|:.|..|:.:| .|....|::|.|:..|.::.....
 Worm   415 ------THELEVERQKTDSILKDMLPRKIAKQLLSGEHLE-PCEYEATVMFCDLPAFQQIIPVCQ 472

  Fly   919 PFEVVEMLNDWYTCCDSIISNYDVYKVETIGDAYMVVSGLPLQNGSRHAGEIASLALHLLETVGN 983
            |..:|::||:.:...|.|:....||||||:.|:||.|||:| ...|.||..:..:||.::....:
 Worm   473 PKNIVKLLNEVFFKLDRIVVLRGVYKVETVSDSYMTVSGIP-DYTSEHAENMCHVALGMMWEARS 536

  Fly   984 LKIRHKPTETVQLRIGVHSGPCAAGVVGQKMPRYCLFGDTVNTASRMESTGDSMRIHISEATYQL 1048
            :......|..: ||||:|||...|||||.|||||||||:||..||:|||.|.:.:|..|..||..
 Worm   537 VMDPVNKTPFL-LRIGLHSGTIIAGVVGTKMPRYCLFGETVTLASQMESLGVAGKIQCSSWTYSK 600

  Fly  1049 LQVIGSYVCIERGLTSIKGKGDMRTYWL---TKRQQPELTP---DLISTVDTLDTYCSGPRESME 1107
            ....|.:....||..::||:||:.||:|   .|:...|:|.   |:  .|::::.|     |.:|
 Worm   601 AMETGRFEFSPRGRINVKGRGDVETYFLMRSLKKSIWEITDHERDV--NVNSIEGY-----EELE 658

  Fly  1108 V------SVHQYCSPASNNYRLGSC 1126
            :      :|.....|.:|.....:|
 Worm   659 IFIENAQTVKHDGHPKANQNHSATC 683

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gyc32E	NP_001097148.1	PBP1_SAP_GC-like	44..448	CDD:380593	18/91 (20%)
		PK_GC-A_B	550..832	CDD:270944	50/298 (17%)
		CYCc	865..1057	CDD:214485	77/191 (40%)
gcy-34	NP_506319.1	HNOB	3..167	CDD:462233	37/190 (19%)
		HNOBA	224..441	CDD:462234	56/294 (19%)
		CYCc	421..609	CDD:214485	77/190 (41%)