Protein Alignment Gyc32E and Npr3

DIOPT Version :9

• Sequence 1: NP_001097148.1
• Gene: Gyc32E / 34553
• FlyBaseID: FBgn0010197
• Length: 1191
• Species: Drosophila melanogaster
• Sequence 2: NP_032754.2
• Gene: Npr3 / 18162
• MGIID: 97373
• Length: 536
• Species: Mus musculus
• Alignment Length: 547
• Identity: 121/547 - (22%)
• Similarity: 226/547 - (41%)
• Gaps: 90/547 - (16%)

  Fly    12 SCILVLLLLGCQRSNPLAAGAT-------VSSMRRLTDTI-------------NIGFLAEYSQMR 56
            :|:|:..:|       ||.||:       ..|.||..:.:             :..:|...:::|
Mouse    11 ACVLLARVL-------LAGGASSGAGDTRPGSRRRAREALAAQKIEVLVLLPRDDSYLFSLARVR 68

  Fly    57 VTLGGLPLAIEDVNKNPNLL-PGKK--LAFKPVDIGHKMSAYRVKPLRAMTQMREAGVTAFIGP- 117
            ..:.....::|.......|| ||.:  :|::..|.|::.....|..:.|   .|.|.....:||
Mouse    69 PAIEYALRSVEGNGTGRKLLPPGTRFQVAYEDSDCGNRALFSLVDRVAA---ARGAKPDLILGPV 130

  Fly   118 -DESCTTEALLASAWNTPMLSFKCSDPIVSNKSTFHTFARTLAPA-SKVSKSVISLLNAFHWNKF 180
             :.:....|.|||.|:.||||.........:|.|.::....:||| :|:.:.:::|....||::.
Mouse   131 CEYAAAPVARLASHWDLPMLSAGALAAGFQHKDTEYSHLTRVAPAYAKMGEMMLALFRHHHWSRA 195

  Fly   181 SIVVSSKPIWGS--DVARAIQELAEARNFTISHFKYISDYIPTTKTLSQIDKIIEETYATTRIYV 243
            ::|.|...:..:  .....:.|:.:......|.:.:     ..||.| .:|.|:.....:.|:.:
Mouse   196 ALVYSDDKLERNCYFTLEGVHEVFQEEGLHTSAYNF-----DETKDL-DLDDIVRYIQGSERVVI 254

  Fly   244 FIGEHIAMVDFVRGLQ---NRRLLESGDYIVVSVDDEIYDSNRRVNIMERNYLD-PYIRKEKSKS 304
            .    .|..|.:|.:.   :|..:.||||...::  |:::|:        :|.| .:.|.:|..|
Mouse   255 M----CASGDTIRRIMLAVHRHGMTSGDYAFFNI--ELFNSS--------SYGDGSWRRGDKHDS 305

  Fly   305 LDKISFRSVIKISMTYPQNPHIRDICSKIKDYARKTPFLVPYHQRVFDNISVPIYGLHLYDSVMI 369
            ..|.::.|:..:::.....|.......::|....|...      ...|.:::.:.|.|  |::::
Mouse   306 EAKQAYSSLQTVTLLRTVKPEFEKFSMEVKSSVEKQGL------NEEDYVNMFVEGFH--DAILL 362

  Fly   370 YVRAITEVLRLGGDIYDGNLVMSHIFNRSYHSIQGFDVYIDSNGDAEGNYTVITL-QNDVGSGAS 433
            ||.|:.||||.|....||..::...:||::..|.| .|.||:|||..|:::|:.: ..:.|:...
Mouse   363 YVLALHEVLRAGYSKKDGGKIIQQTWNRTFEGIAG-QVSIDANGDRYGDFSVVAMTDTEAGTQEV 426

  Fly   434 IGSLAKMSMQPVGFFAYDKNSVIP----EFRYIKNDRPIQWLNGRPPLAEPLCGFHGELCPRKKL 494
            ||..    ....|.|....|...|    :.| :...|.::..|..|      |...|.|   ::.
Mouse   427 IGDY----FGKEGRFQMRSNVKYPWGPLKLR-LDETRIVEHTNSSP------CKSSGGL---EES 477

  Fly   495 DWRYLVSGPLCALVVVVAIALLIKHYR 521
            ....:|.|.|....:::|.....|.||
Mouse   478 AVTGIVVGALLGAGLLMAFYFFRKKYR 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gyc32E	NP_001097148.1	PBP1_Speract_GC_like	44..448	CDD:107365	94/429 (22%)
		ANF_receptor	59..427	CDD:279440	88/380 (23%)
		PHA02988	534..826	CDD:165291
		PK_GC-A_B	550..832	CDD:270944
		HNOBA	<847..886	CDD:285003
		CYCc	865..1057	CDD:214485
		Guanylate_cyc	892..1076	CDD:278633
Npr3	NP_032754.2	PBP1_NPR_C_like	49..440	CDD:107381	95/426 (22%)
		ANF_receptor	66..419	CDD:279440	89/384 (23%)
		TM_EphA1	471..502	CDD:214014	6/33 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2114
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810