Protein Alignment Gyc32E and gcy-33

DIOPT Version :9

• Sequence 1: NP_001097148.1
• Gene: Gyc32E / 34553
• FlyBaseID: FBgn0010197
• Length: 1191
• Species: Drosophila melanogaster
• Sequence 2: NP_001256392.1
• Gene: gcy-33 / 179644
• WormBaseID: WBGene00001553
• Length: 947
• Species: Caenorhabditis elegans
• Alignment Length: 745
• Identity: 178/745 - (23%)
• Similarity: 297/745 - (39%)
• Gaps: 180/745 - (24%)

  Fly   516 LIKHYRYEQT------------LAGLLWKVDMKDVTVINLGEYNNPTNKNIFQICRQSILVVGEP 568
            ||.|||..:|            ||.:.:::|:                         .|.|:.:.
 Worm   129 LILHYRSRRTGYLSYVIGQLVELARVFYQLDI-------------------------GIQVLKKK 168

  Fly   569 NKRSFTNIALFRGNIVAMKKIHKKSVDITRSIRKELKLMREVRHENIINFIGASTDHGSVIIFTT 633
            .|..||.:.|         ||...:|    .:.::|||...|:  |:..::...| ...:.:|..
 Worm   169 EKGRFTFVVL---------KISFDNV----GLGQDLKLKERVK--NLNEYLPVDT-KSFLQMFPF 217

  Fly   634 YCA-RGSLEDVLANEDLHLDHM-----FISSLVSDILKGMIYLHDSEIISHGNLRSSNCLIDSRW 692
            :.| ...||.::|.:.| |:.|     .:.:.|.|:.:..|......|:.|     .||
 Worm   218 HIAFNKKLEILMAGQGL-LNLMPNIQGLLMTDVFDLQRPCIKFTAEGIMVH-----QNC------ 270

  Fly   693 VCQISDFGLHELKAGQEEP--------NKSELELKRALCMAPELLRDAYRPGRGSQKGDVYSFGI 749
            |.||.  .||.:....||.        .:.::.|::...|..|                   :|:
 Worm   271 VFQIE--SLHPVVKQTEENITVQINDITEDKVSLEKKTVMDNE-------------------YGL 314

  Fly   750 LLYEMIGRKGPWGDTAYSKEEIIQFVKCPEMLQHGVFRPALTHTHLDIPDYIRKCLCQCWDEDPE 814
            .....:..:||. ....|.|..:....|.......:|:..|........|..|:.:
 Worm   315 ESLPYVTLRGPI-TVLKSSETFLLLATCVVDTLDTMFKMGLYLNDFGESDCNREII--------- 369

  Fly   815 VRPDIRLVRMHLKELQAGLKPNIFDNMLSIMEKYAYNLEGLVQERTNLLYEEKKKTDMLLYQMLP 879
                       :..:|..      |.:.:::|......| ::.|.|..:.|.||....||.||:|
 Worm   370 -----------MATIQKS------DTLKTMLENEKRRSE-VLTEMTREISEAKKTARTLLTQMMP 416

  Fly   880 RPVAELLKRGDPVE-AECFDCVTILFSDIVGFTELCTTSTPFEVVEMLNDWYTCCDSIISNYDVY 943
            ..||:.:.|...|: .|.|:||:|.|..:..|:::......||||.:||..|:..|||:..:.||
 Worm   417 YEVAQTMMRSGSVDHCEAFECVSIGFIRVCDFSKISLFIEAFEVVNLLNTIYSHLDSIVDTHGVY 481

  Fly   944 KVETIGDAYMVVSGLPLQNGSRHAGEIASLALHLLETVGNLKI----RHKPTETVQLRIGVHSGP 1004
            ||||||::||:.:|.|.::.  :..|:.|..  .||.|.::|.    .|...:.|.::.|:.:||
 Worm   482 KVETIGESYMISAGCPYRDD--YDAEMVSDC--CLEMVSHIKSFEYQSHDAVKKVLIKCGIFTGP 542

  Fly  1005 CAAGVVGQKMPRYCLFGDTVNTASRMESTGDS-MRIHISEATYQLL--QVIGSYVCIERGLTSIK 1066
            ...||||.:.||||||||||||||||||:..: |.|.|.:.|...:  |..|::....:|...:|
 Worm   543 VVGGVVGVRTPRYCLFGDTVNTASRMESSNQTPMTIQIGQRTKDRVEKQASGAFRIKPKGNVFVK 607

  Fly  1067 GKGDMRTYWLTKRQ-----------QPELTPDLISTVDTLDTYCSGPR----------ESMEVSV 1110
            ||||||.|.:.|::           :.::..:.....:.||....|.|          ||::.|.
 Worm   608 GKGDMRVYEIEKKKGRARYKKSDPLRKKMVAEKKEAEELLDEDNEGHRSSALSRMSLGESIDSSS 672

  Fly  1111 HQYCSPASNNYRLGSCNCDTKCLYSRRS---------DDNVTNSHGTSEFPKVSEP--------- 1157
            .:..|.:.:...|......|..|.|:.|         ::|...:...|....:.:|
 Worm   673 SRRGSLSGSQLELNKTIAQTIELTSKASAALDLNMQDENNRPPTWSASHSQDIRKPRKTESKITL 737

  Fly  1158 -AQVNCNQLCVCRLNSSQMFNNRGPRSAPS 1186
             ::::.:.|.|.|:.:|:..:...||...|
 Worm   738 NSRLSSSDLAVSRVETSKDSDGETPRPTSS 767

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gyc32E	NP_001097148.1	PBP1_Speract_GC_like	44..448	CDD:107365
		ANF_receptor	59..427	CDD:279440
		PHA02988	534..826	CDD:165291	51/305 (17%)
		PK_GC-A_B	550..832	CDD:270944	51/295 (17%)
		HNOBA	<847..886	CDD:285003	13/38 (34%)
		CYCc	865..1057	CDD:214485	80/199 (40%)
		Guanylate_cyc	892..1076	CDD:278633	78/191 (41%)
gcy-33	NP_001256392.1	HNOB	2..164	CDD:377902	10/59 (17%)
		HNOBA	204..423	CDD:369471	52/280 (19%)
		CYCc	402..598	CDD:214485	80/199 (40%)
		COG5134	<595..744	CDD:227463	26/148 (18%)
		TDA11	<710..>898	CDD:293689	10/58 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910