Protein Alignment Gyc32E and gc2

DIOPT Version :10

• Sequence 1: NP_001097148.1
• Gene: Gyc32E / 34553
• FlyBaseID: FBgn0010197
• Length: 1191
• Species: Drosophila melanogaster
• Sequence 2: XP_021333059.1
• Gene: gc2 / 140425
• ZFINID: ZDB-GENE-011128-8
• Length: 1120
• Species: Danio rerio
• Alignment Length: 1158
• Identity: 368/1158 - (31%)
• Similarity: 558/1158 - (48%)
• Gaps: 193/1158 - (16%)

  Fly    11 FSCILVLLLLGCQRSNPLAAGATVSSMRRLTDTINIGFLAEYSQMRVTLGGLP-----LAIEDVN 70
            :.|:|...::.|......||            ||.:|.:..:|...:.....|     ||:..:|
Zfish    37 YLCLLWSTIILCLLPATNAA------------TIKVGVVGPWSCDPIFTKAQPGVAARLAVAHIN 89

  Fly    71 KNPNLLPGKKLAFKPVDIGHKMSAYRVKPLRAMTQMREAGVTAFIGPDES--CTTEALLASAWNT 133
            |:|.|..|....:..:|...:.|....:.|...|:     .:.||||...  |...:||..:||.
Zfish    90 KDPYLSQGITFDYIILDEDCETSKSFARFLGYYTR-----ASGFIGPVNPGYCEAASLLGKSWNK 149

  Fly   134 PMLSFKCSDPIVSNKSTFHTFARTLAPASKVSKSVISLLNAFHWNKFSIVVSSKPIW---GSDVA 195
            .:.|:.|.:..:.:..:..|||||:...|.|   ::|.:..|.|....|:.||:.:|   ...:|
Zfish   150 AVFSWSCIEHELDDVRSHPTFARTMPVPSLV---LLSFMRHFRWAHVGIISSSEDVWVEAAIKLA 211

  Fly   196 RAIQE-------LAEARNFTISHFKYISDYIPTTKTLSQIDKIIEETYATTRIYVFIGEHIAMVD 253
            .|::.       :..|||          |:....:||:::.|:     |..|:.:.:...:
Zfish   212 NALRSHGLPVGIVTSARN----------DHTSVRQTLAKVRKV-----ADLRLVILVMHSV---- 257

  Fly   254 FVRGLQNRRLLES--------GDYIVVSVDDEIYDSNRRVNIMERNYLDPYIRKEKSKSLDKISF 310
            .:.|...:.|||:        |..:.:|.|...|      ::...:...|.:| ..||.|.  ::
Zfish   258 LIGGRTQKLLLETAHDMRMTDGSLVFMSYDTLFY------SLPYHHVTQPALR-YNSKLLR--AY 313

  Fly   311 RSVIKISMTYPQNPHIRDICSKIKDYARKTPFLVPYHQRVFDNISVPIYGLHLYDSVMIYVRAIT 375
            .:|:.|::..|:.........|.::.......|.|  |:|     .|::|. :|.|::....|:.
Zfish   314 DAVLTITIESPKEQSFYQAFEKAQEDGELPKHLKP--QQV-----SPLFGT-IYSSIVFMAHAVQ 370

  Fly   376 EVLRLGGDIYDGNLVMS--HIFNRSYHSIQGFDVYIDSNGDAEGNYTVITLQNDVGSGASIGSLA 438
            .|...|..:..||:..:  ::..:...|:|       :|....|....:.|..|   |.|
Zfish   371 SVRAAGQWMSGGNIAQNARNLLFKGGSSLQ-------ANSSDFGMLDYVILDTD---GFS----- 420

  Fly   439 KMSMQPVGFFAYDKNSVIPEFRYIKNDRPIQWLNGRPPLAEPLCGF-HGELCP------------ 490
             ..:||........:.|    |::  .|.|.:....||..:..|.| ||.:|.
Zfish   421 -WELQPTYRIEMQTDMV----RFL--GRHIHFPYAGPPRTDSSCWFTHGIICRGGVNLFHMISMF 478

  Fly   491 -----------------RKKLDWRYLVSGPLCALVVVVAIALLIKHYRYEQTLAGLLWKVDMKDV 538
                             |:|::...||.||...|:.                         :.||
Zfish   479 LLGFLFIFLSIGCSYCIRRKINKIRLVRGPNKILLT-------------------------LNDV 518

  Fly   539 TVINLGEYN----------NPTNKNIFQICRQSILVVGEPNKRSFTNIALFRGNIVAMKKI-HKK 592
            |.||....|          :.|..:|.:....|.:....|.....:|:|::.|:...||:: :..
Zfish   519 TFINPSLSNKKLSVDDSKASDTRMSISERSLVSPMSSQSPATYENSNVAIYEGDWAWMKRLPYGT 583

  Fly   593 SVDITRSIRKELKLMREVRHENIINFIGASTDHGSVIIFTTYCARGSLEDVLANEDLHLDHMFIS 657
            ...||.:.....:||:::|||||..|:|...|.|...|.|.:|:||||||:|.|:|:.||.||.|
Zfish   584 FRSITPNTSDVFELMKDLRHENINPFLGFFHDCGVFAIVTEFCSRGSLEDLLVNDDVKLDWMFKS 648

  Fly   658 SLVSDILKGMIYLHDSEIISHGNLRSSNCLIDSRWVCQISDFGLHELKAGQE----EPNKSELEL 718
            ||:.|::|||.|||... :.||.|:|.||::|.|:|.:|:|:|.:|:...|.    ||...:|
Zfish   649 SLILDLIKGMKYLHHRN-VCHGRLKSRNCVVDGRFVLKITDYGYNEVLESQRFPYIEPPAEDL-- 710

  Fly   719 KRALCMAPELLRDAYRPG-RGSQKGDVYSFGILLYEMIGRKGPWGDTAYSKEEIIQFVKCPEMLQ 782
               |..|||:||.:| || .|:..||||||.|::.|::.|..|:.....:.:||:|.|:.|..:
Zfish   711 ---LWTAPEILRGSY-PGLHGTHSGDVYSFSIIMQEVVMRGPPFCMLENTFDEIVQKVRKPPPM- 770

  Fly   783 HGVFRPALTHTHLDIPDYIRKCLCQCWDEDPEVRPDIRLVRMHLKELQAGLKPNIFDNMLSIMEK 847
               .||.::..|  .|....:.:.|||:|.||.||....:....|.:..|.|.||.|:||.::|:
Zfish   771 ---CRPIVSPDH--APMECIQLMKQCWNEQPEKRPTFDEIFDQFKNVNKGKKTNIIDSMLRMLEQ 830

  Fly   848 YAYNLEGLVQERTNLLYEEKKKTDMLLYQMLPRPVAELLKRGDPVEAECFDCVTILFSDIVGFTE 912
            |:.|||.|::|||..|..||:||:.||.||||..|||.||.|..||.|.|:.|::.||||||||.
Zfish   831 YSSNLEELIRERTEELEIEKQKTEKLLTQMLPPSVAEALKLGTTVEPEHFESVSLYFSDIVGFTT 895

  Fly   913 LCTTSTPFEVVEMLNDWYTCCDSIISNYDVYKVETIGDAYMVVSGLPLQNGSRHAGEIASLALHL 977
            :...|.|.|||::|||.||..|::|.|:||||||||||||||.||:|:.||:|||.|||::||.:
Zfish   896 ISANSEPIEVVDLLNDLYTTFDAVIGNHDVYKVETIGDAYMVASGVPVPNGNRHAAEIANMALDI 960

  Fly   978 LETVGNLKIRHKPTETVQLRIGVHSGPCAAGVVGQKMPRYCLFGDTVNTASRMESTGDSMRIHIS 1042
            |..||..::||.|...|::|||:|:|||.|||||..|||||||||||.|||||||||...|||:.
Zfish   961 LSAVGTFRMRHMPDVPVRIRIGLHTGPCVAGVVGLTMPRYCLFGDTVTTASRMESTGLPYRIHVH 1025

  Fly  1043 EATYQLLQVIGSYVCIE-RGLTSIKGKGDMRTYWLTKRQ---QPELTPDLIST 1091
            .:|.::|..:.....:| |..|.:|||....|||||.|.   :|...|.::.:
Zfish  1026 SSTVKILMELKLGYRVELRARTELKGKRIEETYWLTGRDGFTKPLPVPPVLKS 1078

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gyc32E	NP_001097148.1	PBP1_SAP_GC-like	44..448	CDD:380593	91/430 (21%)
		PK_GC-A_B	550..832	CDD:270944	103/287 (36%)
		CYCc	865..1057	CDD:214485	113/191 (59%)
gc2	XP_021333059.1	PBP1_sensory_GC_DEF-like	59..440	CDD:380594	92/446 (21%)
		PK_GC-2D	551..815	CDD:270945	101/276 (37%)
		HNOBA	<824..869	CDD:462234	25/44 (57%)
		CYCc	848..1040	CDD:214485	113/191 (59%)