Protein Alignment Gyc32E and adcy4

DIOPT Version :9

• Sequence 1: NP_001097148.1
• Gene: Gyc32E / 34553
• FlyBaseID: FBgn0010197
• Length: 1191
• Species: Drosophila melanogaster
• Sequence 2: XP_002934331.3
• Gene: adcy4 / 100497212
• XenbaseID: XB-GENE-984909
• Length: 1072
• Species: Xenopus tropicalis
• Alignment Length: 1106
• Identity: 225/1106 - (20%)
• Similarity: 390/1106 - (35%)
• Gaps: 356/1106 - (32%)

  Fly   165 SKSVISLLNAFHWNKFSIV--VSSKPI---WGSDVARAIQELAEARNFTISHFKYISDYIPTTKT 224
            :..::|..:..:|..|.|:  .:..|:   |.         :....:..::|...:|.|:.|.:.
 Frog   116 TSGLVSAWDQIYWTLFVIISLYTMLPLGMKWA---------IFAGLSCFVAHIIVLSVYVSTVRL 171

  Fly   225 LSQID---------------------------KIIEETYATTRIYVFIGEHIAMVDFVRGLQNRR 262
            |.:.|                           ..:::||  .....||...:.:|...|  |..|
 Frog   172 LPRDDVALQMIADAVILLCGNVIGGYHKCVTESALKDTY--HEAINFIHSRLKLVSQER--QQER 232

  Fly   263 LLES--GDYIVVSVDDEIYDSNRRVNIMER--------NYLDPYIRKEKSKSL---DKISF---- 310
            ||.|  ..||...:..||.:     .:.|:        |:.:.||::.|..|:   |.:.|
 Frog   233 LLLSILPAYIATEMKAEIIE-----RLKEKRPQPENTNNFHNLYIKRHKDVSILYADIVGFTLLS 292

  Fly   311 ------RSVIKISMTYPQNPHIR--DICSKIKDY------ARKTPFLVPYHQRVFDNISVPIYGL 361
                  ..|:.::..:.:...|.  :.|.:||..      ....|..:|.|.:     :..:.||
 Frog   293 SECSPKELVLMLNELFGKFDQIAKDNECMRIKILGDCYYCVSGLPEFLPNHAK-----NCVLMGL 352

  Fly   362 HLYDSVMIYVRAITEV---LRLGGDIYDGNLVMSHI-FNRSYHSIQGFDVYIDSNGDAEG----- 417
            .:..::. .:|..|.|   :|:|  ::.||::...| ..:..:.:...||.:.::.:|.|
 Frog   353 DMCQAIR-KLRKATGVDINMRVG--VHSGNVLCGVIGLQKWQYDVWSHDVTLANHMEAGGVPGRV 414

  Fly   418 ---NYTVITLQNDVGSGASIGSLAKMSMQPVGFFAY-----------------DKNSVIPEF--- 459
               ..|:..|:|:.....:..:...:.::......|                 .|::.:|:.
 Frog   415 HITEATLSHLENEYEVEDATLAQRDLYLKENNIKTYLVIDPRANDGEAEDILPSKSAEVPKMRAS 479

  Fly   460 ----RYIKN---DRPIQWLNGRPPLA-EPLCGFHGELCPRKKLDWRYLVSGPLCALVVVVAIALL 516
                ||:::   ::|...|:.|..|. ||....|....|...|
 Frog   480 VRMTRYLESWGAEKPFAHLSHRDSLVPEPHSISHSMDLPMSPL---------------------- 522

  Fly   517 IKHYRYEQTLAGLLWKVDMKDVTVINLGEYNNPTNKNIFQICRQSILVVGEPNKRS--FTNIALF 579
                  .||     |..:....|    .|.|...|.|.|.|  ..:|......|||  |..|.|:
 Frog   523 ------SQT-----WSQEKSRST----RETNESLNDNNFHI--MEVLASQRQWKRSKDFNRITLY 570

  Fly   580 RGNIVAMKKIHKKSVDITRSIRKELKLMREVRHENIINFIGASTDHGSVIIFTTYC----ARGSL 640
            ..:               ::..||.:|                :|..|...:|..|    |...:
 Frog   571 FND---------------KAAEKEYRL----------------SDLPSFKYYTACCFFIFACNFI 604

  Fly   641 EDVLANED----------------LHLDHMFISSLVSDILKGMIYLHDSEIISHGNLRSSNCLID 689
            ..:|.:..                |.|...|...|...||||...||        .|.|.:..:.
 Frog   605 VQILVSHKNAAFGISYGISFFFFLLLLFTCFAGHLARCILKGPQLLH--------WLPSLSIALS 661

  Fly   690 SR-W------------VCQISDFGLHEL---KAGQEEPNKS-----ELELKRAL------CMAPE 727
            || |            |..::.|.|..|   ...|:..|.|     |.::..:|      |:...
 Frog   662 SRPWLRVPLGVFTILTVLVMAVFNLFFLPDNNCPQQSWNSSLSPDPEPQMLYSLPYYMYCCILGL 726

  Fly   728 LLRDAYRPGRGSQKGDVYSFGILLYEMIGRKGPWGDTAYSKEEIIQFVKCPEMLQHGVFRPALTH 792
            |...|:.......|..:.|..:::|.:|                                  ...
 Frog   727 LACSAFLLMNFEAKLILLSIALVIYNVI----------------------------------FLE 757

  Fly   793 THLDIPD-YIRKCLCQCWDEDPEVRPDIRLVRMHLKELQAGLKPNI---------FDNMLSIMEK 847
            ||..:.| |:.      |......||.|      |||      |.:         |..:|::..:
 Frog   758 THSWLSDCYVN------WLYMNHSRPGI------LKE------PKVMGSISLFIFFFTLLALSRQ 804

  Fly   848 YAYNLEGLVQERTNLLYEEKKKTD------------MLLYQMLPRPVAELL----KRGDPVEAEC 896
            ..|..      |.:.|::.|.|.:            :||..:||..||:..    :|.:.:..:.
 Frog   805 NEYYC------RLDFLWKRKFKMERERIETMENLNRVLLENVLPADVAQQFIGQNRRNEDLYYQS 863

  Fly   897 FDCVTILFSDIVGFTELCT----TSTPFEVVEMLNDWYTCCDSIISN---YDVYKVETIGDAYMV 954
            :|||.:||:.|..|.|..|    .....|.:.:||:.....|.::|.   ..|.|::|||.|||.
 Frog   864 YDCVCVLFASIPDFKEFYTECDENHEGLECLRLLNEIIADFDELLSKPKFSSVEKIKTIGSAYMA 928

  Fly   955 VSGLPL-------QNGSRHAGEIASLALHLLETVGNLKIRHKPT-ETVQLRIGVHSGPCAAGVVG 1011
            .:||..       |:|.|:...|..:....:..:|.|.:.:|.: ...:||:|::.||..|||:|
 Frog   929 ATGLNATSGQENPQDGDRNYNHIGIMVEFAIALIGKLDLINKHSFNNFKLRVGINHGPVVAGVIG 993

  Fly  1012 QKMPRYCLFGDTVNTASRMESTGDSMRIHISEATYQLLQVIGSYVCIERGLTSIKGKGDMRTYWL 1076
            .:.|:|.::|:|||.||||:|||...:|.::|.|.::|:.:| |.|..||:..:||||.:.||::
 Frog   994 AQKPQYDIWGNTVNVASRMDSTGVLGKIQVTEETTKVLEKLG-YKCERRGVIKVKGKGQLCTYFV 1057

  Fly  1077 T 1077
            :
 Frog  1058 S 1058

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gyc32E	NP_001097148.1	PBP1_Speract_GC_like	44..448	CDD:107365	60/357 (17%)
		ANF_receptor	59..427	CDD:279440	59/336 (18%)
		PHA02988	534..826	CDD:165291	62/341 (18%)
		PK_GC-A_B	550..832	CDD:270944	62/331 (19%)
		HNOBA	<847..886	CDD:285003	11/50 (22%)
		CYCc	865..1057	CDD:214485	68/222 (31%)
		Guanylate_cyc	892..1076	CDD:278633	68/198 (34%)
adcy4	XP_002934331.3	AC_N	<17..250	CDD:318454	25/146 (17%)
		Guanylate_cyc	270..427	CDD:306677	30/164 (18%)
		DUF1053	483..586	CDD:399378	32/172 (19%)
		Guanylate_cyc	859..1057	CDD:306677	68/198 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910