Protein Alignment Gyc32E and gucy2f

DIOPT Version :9

• Sequence 1: NP_001097148.1
• Gene: Gyc32E / 34553
• FlyBaseID: FBgn0010197
• Length: 1191
• Species: Drosophila melanogaster
• Sequence 2: XP_002931862.2
• Gene: gucy2f / 100492820
• XenbaseID: XB-GENE-480268
• Length: 1112
• Species: Xenopus tropicalis
• Alignment Length: 1106
• Identity: 365/1106 - (33%)
• Similarity: 553/1106 - (50%)
• Gaps: 182/1106 - (16%)

  Fly    64 LAIEDVNKNPNLLPGKKLAFKPVDIGHKMSAYRVKPLRAMTQMREAGV-TAFIGPDES--CTTEA 125
            ||||.:||:.:|..|  |:|..|.:.......:.    ..|.:..:|| :.||||...  |....
 Frog    82 LAIERINKDASLDLG--LSFNYVILEEDCQTSKA----LSTFLTYSGVASGFIGPSNPGYCDAAT 140

  Fly   126 LLASAWNTPMLSFKCSDPIVSNKSTFHTFARTLAPASKVSKSVISLLNAFHWNKFSIVVSSKPIW 190
            ||...||..:.|:.|.:..:.|..::.||||||...::|   :.:::..|.|....::.|::.||
 Frog   141 LLGKNWNKAVFSWACINYELDNVKSYPTFARTLPSPTRV---LFNVMKYFQWAHVGVISSNEDIW 202

  Fly   191 GSDVARAIQELAEARNFTISHFKYISDYIPTT-KTLSQIDKIIEETYATTRIYVFIGEHIAMV-- 252
             .|..|.:.....:....:.....:.|.|.:| :.|.::.||               ::|.|:
 Frog   203 -RDTGRKVANALRSNGLPVGIVVSMGDDIRSTQQALEKVRKI---------------DNIRMIIM 251

  Fly   253 ----DFVRGLQNRRLLE--------SGDYIVVSVDDEIYDSNRRVNIMERNYLDPYIRK-----E 300
                ..:.|...:||||        .|.|:.|..|...|..             ||.:.     :
 Frog   252 CMHSVLIGGQAQQRLLEVAHDLKMTDGTYVFVPYDTLYYSL-------------PYHKTTYDMLK 303

  Fly   301 KSKSLDKISFRSVIKISMTYPQNPHIRDICSKIKDYARKTPFLVPYHQRVFDNISVPIYGLHLYD 365
            .|.:| ..::.||:.|::. .:.....:...:.::.......:.|      ..:| |::|. :|:
 Frog   304 NSPNL-TAAYDSVLTITVE-SEGKTFYEAFQEAQESGEMNANIKP------SQVS-PLFGT-IYN 358

  Fly   366 SVMIYVRAITEVLRLGGDIYDGNLVMSHIFNRSYHSIQGFDVYI--DSNGDAEGNYTVITLQNDV 428
            ::.....|:....|.|..: .|:.::.|..|..::   ||:.:|  |.:|:...:|.::.
 Frog   359 AIYFTAYAMNSSRRQGTWV-SGSSLVKHSKNMQFY---GFNQWIKTDMSGNGFTDYVILD----- 414

  Fly   429 GSGASIGSLAKMSMQPVGFFAYDKNSVIPEFRYIKNDRPIQWLNGRPPLAEPLCGF-HGELCPRK 492
                     |.|....: ...|..:......||:  .|||.:.||..|..:..|.| .|::|
 Frog   415 ---------ADMKTNEL-HRTYVVDMETDMVRYM--GRPIHFPNGVSPKTDSYCWFSDGKIC--- 464

  Fly   493 KLDWRYLVSG--PLCALVVVVAIALLIKHYRYEQTLAGLLWKV------------------DMKD 537
                   ..|  |..||:|.:.|.:.|      .:|.||.:.:                  .::|
 Frog   465 -------TGGIEPAFALMVFLCIVVAI------ISLNGLAYVIRRRINKIKLVRGPNKILLTLED 516

  Fly   538 VTVIN-------LGEYNNPTNKN--IFQICR-----------QSILVVGEPNKRSFTNIALFRGN 582
            ||.||       |....:.|:.:  :....|           ||::    |.....:|:|::.|:
 Frog   517 VTFINPQLSVKKLSNDGSRTSDSGPVLTDTRSMKSPMRSGSTQSLI----PATYENSNVAIYEGD 577

  Fly   583 IVAMKKIHKKSV-DITRSIRKELKLMREVRHENIINFIGASTDHGSVIIFTTYCARGSLEDVLAN 646
            .|.|||...... ::........:.|:::||||:..|:|...|.|...|.|.:|:||||||:|.|
 Frog   578 WVWMKKFPSGDFGELKPGTSDVFETMKDMRHENVNPFLGFFHDCGVFAIVTEFCSRGSLEDLLRN 642

  Fly   647 EDLHLDHMFISSLVSDILKGMIYLHDSEIISHGNLRSSNCLIDSRWVCQISDFGLHELKAGQ--- 708
            :|:.||.||.|||:.|::|||.|||..:.: ||.|:|.||::|.|:|.:::|:|.:|:...|
 Frog   643 QDVKLDWMFKSSLLLDLIKGMKYLHHRKFV-HGRLKSRNCVVDGRFVLKVTDYGYNEVLEAQRIP 706

  Fly   709 -EEPNKSELELKRALCMAPELLRDAYRPGRGSQKGDVYSFGILLYEMIGRKGPWGDTAYSKEEII 772
             |||...||     |..|||||||......||..||||||.:::.|::.|..|:.....:.||||
 Frog   707 HEEPTAYEL-----LWTAPELLRDPLSAVHGSFSGDVYSFSVIMQEVVVRGPPFCTVEDTAEEII 766

  Fly   773 QFVKCPEMLQHGVFRPALTHTHLDIPDYIRKCLC---QCWDEDPEVRPDIRLVRMHLKELQAGLK 834
            |.||.|..|    .||.::..|..:     :|:.   :||:|.|:.||....:....|.:..|.|
 Frog   767 QKVKKPPPL----CRPMVSPDHAPM-----ECIILMKKCWNEVPDRRPSFDEIFDQFKNINKGRK 822

  Fly   835 PNIFDNMLSIMEKYAYNLEGLVQERTNLLYEEKKKTDMLLYQMLPRPVAELLKRGDPVEAECFDC 899
            .||.|:||.::|:|:.|||.|::|||..|..||:||:.||.||||..|||.||.|..||.|.||.
 Frog   823 TNIIDSMLRMLEQYSSNLEDLIRERTEELEIEKQKTEKLLTQMLPPSVAEALKMGCTVEPEGFDE 887

  Fly   900 VTILFSDIVGFTELCTTSTPFEVVEMLNDWYTCCDSIISNYDVYKVETIGDAYMVVSGLPLQNGS 964
            ||:.||||||||.:...|.|.|||::|||.||..|::|.|:||||||||||||||.||||.:||:
 Frog   888 VTLYFSDIVGFTSISAMSEPIEVVDLLNDLYTLFDAVIGNHDVYKVETIGDAYMVASGLPKRNGN 952

  Fly   965 RHAGEIASLALHLLETVGNLKIRHKPTETVQLRIGVHSGPCAAGVVGQKMPRYCLFGDTVNTASR 1029
            |||.|||:::|.:|.:||:.|:||.|...|::|||:||||..|||||..||||||||||||||||
 Frog   953 RHAAEIANMSLDILSSVGSFKMRHMPDVPVRIRIGLHSGPAVAGVVGLTMPRYCLFGDTVNTASR 1017

  Fly  1030 MESTGDSMRIHISEATYQLLQVIGSYVCIE-RGLTSIKGKGDMRTYWLTKRQ---QPELTPDLIS 1090
            |||||...|||::::|.:.|:.:.....:| ||.|.:||||...|:||..::   :|...|.:|.
 Frog  1018 MESTGLPYRIHVNQSTVKTLRSLNEGYLLELRGRTELKGKGIEETFWLVGKEGFTKPLPVPPVIK 1082

  Fly  1091 T 1091
            :
 Frog  1083 S 1083

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gyc32E	NP_001097148.1	PBP1_Speract_GC_like	44..448	CDD:107365	84/408 (21%)
		ANF_receptor	59..427	CDD:279440	82/387 (21%)
		PHA02988	534..826	CDD:165291	109/319 (34%)
		PK_GC-A_B	550..832	CDD:270944	104/302 (34%)
		HNOBA	<847..886	CDD:285003	22/38 (58%)
		CYCc	865..1057	CDD:214485	117/191 (61%)
		Guanylate_cyc	892..1076	CDD:278633	110/184 (60%)
gucy2f	XP_002931862.2	PBP1_sensory_GC_DEF-like	58..439	CDD:380594	87/425 (20%)
		PK_GC-2D	553..820	CDD:270945	102/285 (36%)
		HNOBA	<829..874	CDD:400168	25/44 (57%)
		CYCc	853..1044	CDD:214485	117/190 (62%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D123766at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010