Sequence 1: | NP_523544.2 | Gene: | hgo / 34552 | FlyBaseID: | FBgn0040211 | Length: | 439 | Species: | Drosophila melanogaster |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_694498.2 | Gene: | hgd / 259189 | ZFINID: | ZDB-GENE-020802-5 | Length: | 443 | Species: | Danio rerio |
Alignment Length: | 435 | Identity: | 296/435 - (68%) |
---|---|---|---|
Similarity: | 350/435 - (80%) | Gaps: | 2/435 - (0%) |
- Green bases have known domain annotations that are detailed below.
Fly 1 MSEYKYLSGFGSHFSSEDERYPNSLPVGQNSPQVCPYKLYAEQLSGSAFTAPRTENMRTWLYRKL 65
Fly 66 PSAAHLPFQPFKGAEYFSQNWDEQPPNPNQLRWKPFDLPPKDGKNVNFVEGLHTVCGAGDPRSRH 130
Fly 131 GLAIHIYSCNGSMDNSAFYNSDGDFLIVPQQGVLDITTEFGRMSVAPNEICVIPQGIRFAVNVDS 195
Fly 196 PSRGYILEVYDDHFVLPDLGPIGANGLANPRDFETPVAWFDDRDV-KDFQVISKFQGRLFVAKQN 259
Fly 260 HTVFDVVAWHGNYVPFKYDLSKFMVINSVSFDHCDPSIFTVLTCPSLRAGTAIADFVIFPPRWSV 324
Fly 325 QEHTFRPPYYHRNCMSEFMGLILGKYEAKEDGFAAGGATLHSMMTPHGPDVKCFEGASNAKLVPE 389
Fly 390 RVAEGTQAFMFESSLSLAVTKWGEETCQKLDAAYYECWQALKNNF 434 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
hgo | NP_523544.2 | hmgA | 3..434 | CDD:273395 | 294/431 (68%) |
hgd | NP_694498.2 | homogentisate 1,2-dioxygenase. Homogentisate dioxygenase cleaves the aromatic ring during the metabolic degradation of Phe and Tyr. Homogentisate dioxygenase deficiency causes alkaptonuria. The structure of homogentisate dioxygenase shows that the enzyme forms a hexamer arrangement comprised of a dimer of trimers. The active site iron ion is coordinated near the interface between the trimers | 4..434 | 294/430 (68%) | |
hmgA | 4..434 | CDD:273395 | 294/430 (68%) |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 1 | 0.930 | - | - | C170580263 | |
Domainoid | 1 | 1.000 | 597 | 1.000 | Domainoid score | I193 |
eggNOG | 1 | 0.900 | - | - | E1_COG3508 | |
Hieranoid | 1 | 1.000 | - | - | ||
Homologene | 1 | 1.000 | - | - | H156 | |
Inparanoid | 1 | 1.050 | 618 | 1.000 | Inparanoid score | I858 |
OMA | 1 | 1.010 | - | - | QHG63167 | |
OrthoDB | 1 | 1.010 | - | - | D226335at33208 | |
OrthoFinder | 1 | 1.000 | - | - | FOG0006563 | |
OrthoInspector | 1 | 1.000 | - | - | oto39095 | |
orthoMCL | 1 | 0.900 | - | - | OOG6_102821 | |
Panther | 1 | 1.100 | - | - | LDO | PTHR11056 |
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R2561 |
SonicParanoid | 1 | 1.000 | - | - | X4803 | |
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 1 | 0.960 | - | - | ||
ZFIN | 0 | 0.000 | Not matched by this tool. | |||
16 | 15.800 |