Protein Alignment hgo and hgo-1

DIOPT Version :10

• Sequence 1: NP_523544.2
• Gene: hgo / 34552
• FlyBaseID: FBgn0040211
• Length: 439
• Species: Drosophila melanogaster
• Sequence 2: NP_492433.1
• Gene: hgo-1 / 172726
• WormBaseID: WBGene00001843
• Length: 437
• Species: Caenorhabditis elegans
• Alignment Length: 442
• Identity: 297/442 - (67%)
• Similarity: 348/442 - (78%)
• Gaps: 9/442 - (2%)

  Fly     1 MSEY---KYLSGFGSHFSSEDERYPNSLPVGQNSPQVCPYKLYAEQLSGSAFTAPRTENMRTWLY 62
            |||:   |||:|||:..::.|.|.|::|||||||||.|.:.||||||||:||||||::|.|:|||
 Worm     1 MSEFDELKYLTGFGNEHATSDPRVPDALPVGQNSPQKCSHGLYAEQLSGTAFTAPRSQNQRSWLY 65

  Fly    63 RKLPSAAHLPFQPFK-GAEYFSQNWDEQPPNPNQLRWKPFDLPPKDGKNVNFVEGLHTVCGAGDP 126
            |..||..|.||:..| ..::::.|:...||||||.||.||.||.|:|  |.||:.|:||||.||.
 Worm    66 RIRPSVIHRPFEAMKENDQHWTNNFSSIPPNPNQYRWNPFPLPTKEG--VTFVDNLYTVCGGGDV 128

  Fly   127 RSRHGLAIHIYSCNGSMDNSAFYNSDGDFLIVPQQGVLDITTEFGRMSVAPNEICVIPQGIRFAV 191
            .||.|||||.:|||.||:::|.||||||||||||||.|:|||||||:.|.|.||.||||||||:|
 Worm   129 ISRTGLAIHQFSCNASMEHTAMYNSDGDFLIVPQQGALEITTEFGRLLVNPQEIAVIPQGIRFSV 193

  Fly   192 NVDSPSRGYILEVYDDHFVLPDLGPIGANGLANPRDFETPVAWFDDRDVKDFQVISKFQGRLFVA 256
            .|..||||||||||..||.|||||||||||||||||||.|||||:|.|| :|.:|:|:||..|.|
 Worm   194 AVRGPSRGYILEVYGTHFQLPDLGPIGANGLANPRDFEAPVAWFEDLDV-EFTIINKYQGSWFQA 257

  Fly   257 KQNHTVFDVVAWHGNYVPFKYDLSKFMVINSVSFDHCDPSIFTVLTCPSLRAGTAIADFVIFPPR 321
            ||.|:.||||.|||||||:||||.||||||:|||||||||||||||.||::.|||||||||||||
 Worm   258 KQGHSPFDVVGWHGNYVPYKYDLKKFMVINTVSFDHCDPSIFTVLTAPSVKHGTAIADFVIFPPR 322

  Fly   322 WSVQEHTFRPPYYHRNCMSEFMGLILGKYEAKEDGFAAGGATLHSMMTPHGPDVKCFEGASNAKL 386
            |...::||||||||||||||:||||.|.|||||.||..||.:|||||||||||..|||.||||.|
 Worm   323 WGCADNTFRPPYYHRNCMSEYMGLITGCYEAKEGGFKPGGGSLHSMMTPHGPDFNCFEMASNADL 387

  Fly   387 VPERVAEGTQAFMFESSLSLAVTKWGEETCQKLDAAYYECWQALKNNFQITK 438
            .|:||||||.:|||||||::|:|.|.  ..|.:|..||:.||.||.:|.:.|
 Worm   388 KPQRVAEGTMSFMFESSLNMAITNWA--VYQNVDKDYYKDWQPLKKHFTMPK 437

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hgo	NP_523544.2	hmgA	3..434	CDD:273395	293/434 (68%)
hgo-1	NP_492433.1	hmgA	6..433	CDD:273395	292/431 (68%)