Protein Alignment CG4751 and mpnd

DIOPT Version :10

• Sequence 1: NP_609495.1
• Gene: CG4751 / 34551
• FlyBaseID: FBgn0032348
• Length: 1412
• Species: Drosophila melanogaster
• Sequence 2: NP_001070033.1
• Gene: mpnd / 559169
• ZFINID: ZDB-GENE-060929-1162
• Length: 458
• Species: Danio rerio
• Alignment Length: 449
• Identity: 169/449 - (37%)
• Similarity: 266/449 - (59%)
• Gaps: 40/449 - (8%)

  Fly    81 PPTDGAAPVAILEDNMCDKDVDSDAGDEDNDDETKENYEGFNGTGRTVTLQTLMAANVLQPGLGL 145
            ||   ::|..:.|.  .|::.:..:|.||.|..:... .|...|.|.:||:.|:...:::||.|:
Zfish     5 PP---SSPQVVEEG--ADEEDEELSGAEDADLRSSSG-RGSLLTRRGITLRVLLKDGLVEPGDGV 63

  Fly   146 MTIEYLGQKFVGDLLADGKIKSHETETIFLTPSAWAMHCKRIINPDKKSGCGWASVKYKGKKLDA 210
            ::|.|||:|||||||.||||:..||..||.:|||||.||||::||.||||||||||:|:|:||..
Zfish    64 LSIHYLGKKFVGDLLNDGKIRWVETGQIFNSPSAWATHCKRLVNPAKKSGCGWASVRYRGQKLVQ 128

  Fly   211 YKNTYLRKCALQKETPL----DDCEL----DAERKTDTP-------------EIVV------KRT 248
            ||.|:|.|.....:..|    :|.|:    :.|.||..|             ||.:      :|.
Zfish   129 YKTTWLHKYQPSADMSLISEGEDDEMGDDDEEEGKTTIPVEDKNKKSKPELHEIGLTQRRDRERI 193

  Fly   249 VFAHNTVSNRNVVHDANMLIESVPFTSVGKLQPFLITVNSSALLLADFHCHLTVREVCGYLGGTW 313
            ...:.|:..|:...|.:.|:|...|:::.:.|||.:.|:|:.|||.|||||||..||.|||||.|
Zfish   194 PVRYCTLGTRDAARDPHTLVELSAFSAINRFQPFNVAVSSNVLLLMDFHCHLTSSEVVGYLGGRW 258

  Fly   314 DMNTHTLSITKTYPCRSTRFDRQRAGEVERDIQKMMIQDQLLLVGWYHSHPKFQAEPTLRDCDAQ 378
            |.||..|::.:.:|||:...|:..|..||.:|.:.:....|.|||||||||:..|.|:|:|.|:|
Zfish   259 DTNTQLLTVLRAFPCRTRLADKDAAPAVEEEICQNLFMRGLSLVGWYHSHPRGPALPSLQDIDSQ 323

  Fly   379 LDYQIKMRGASDLTYTPCVSLIISPYYDENPTLESVVKCIWIVPPNENRQSMEYGRPMLMQYSVL 443
            :|:|::::|:|: .:.||:.:|..|||..|..:.|.:...|:|||.|.|.: ::|.|:.::.:.:
Zfish   324 MDHQLRLQGSSN-GFQPCLGIICGPYYHGNQGVASTITPFWVVPPPEQRPN-DHGIPVAVEVTYV 386

  Fly   444 PDKEIPEEVRSEIQLCVDYYSQYRS--EMVKFRNIYNNDVTYNEKLKNTLYPKFPSKQS 500
            .|..:..:|.:|:.|.|::   |||  ::|:|..:::.:.:..:|:|.:|....|..|:
Zfish   387 QDNFLTTDVLNEMMLLVEF---YRSAPDLVQFSQMWSPNTSILDKIKASLSGHAPKDQA 442

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4751	NP_609495.1	RAMA	124..220	CDD:465856	57/95 (60%)
		MPN_2A_DUB	278..463	CDD:163698	76/184 (41%)
		PHA03247	<616..741	CDD:223021
mpnd	NP_001070033.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..37		9/37 (24%)
		RAMA	28..139	CDD:465856	60/111 (54%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	147..175		6/27 (22%)
		MPN_2A_DUB	223..407	CDD:163698	76/188 (40%)
		JAMM motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU01182	306..319		7/12 (58%)